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China Most Professional Factory Supply High Qulity Cholecalciferol(Vitamin D3) CAS 67-97-0

Name: China Most Professional Factory Supply High Qulity Cholecalciferol(Vitamin D3) CAS 67-97-0
Brand: Leader
SKU: pr2312051010
Price: 1 USD
Availability: InStock

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Unit Price:

$1/KG FOB

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CAS No.:

67-97-0

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Shanghai

Brand:

Leader

Packaging:

25KG/Drum

Sample Available:

Yes

Price valid (until):

2059-12-31

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LEADER BIOCHEMICAL GROUP

Company Type:

Manufactory

Location:

China

Payment Terms:

TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

5 days

Qualification:

Main Products:

Biochemicals Ingredients,Vitamin Amino Acid Ingredients,Cosmestic Ingredients,Pharma Chemicals,Organic Fine Chemicals,Food Nutrient Ingredients

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Product Description
Seller Information
Inquiry History

Description

About Product Technical Details

Vitamin D3 Chemical Properties

Melting point	83-86 °C(lit.)
Boiling point	451.27°C (rough estimate)
alpha	105 º (c=0.8, EtOH 25 ºC)
density	0.9717 (rough estimate)
vapor pressure	2.0 x l0^-6 Pa (20 °C, est.)
refractive index	1.5100 (estimate)
Fp	14 °C
storage temp.	-20°C
solubility	Practically insoluble in water, freely soluble in ethanol (96 per cent), soluble in trimethylpentane and in fatty oils. It is sensitive to air, heat and light. Solutions in solvents without an antioxidant are unstable and are to be used immediately. A reversible isomerisation to pre-cholecalciferol takes place in solution, depending on temperature and time. The activity is due to both compounds.
form	powder
pka	14.74±0.20(Predicted)
color	White
Odor	odorless
Water Solubility	<0.1 g/L (20 ºC)
Sensitive	Air & Light Sensitive
Merck	14,10019
BRN	2339331
Stability:	Light Sensitive, Temperature Sensitive
InChIKey	QYSXJUFSXHHAJI-YRZJJWOYSA-N
LogP	9.085 (est)
CAS DataBase Reference	67-97-0(CAS DataBase Reference)
NIST Chemistry Reference	Cholecalciferol(67-97-0)
EPA Substance Registry System	Cholecalciferol (67-97-0)

D-Glucosamine hydrochloride Chemical Properties

Melting point	190-194 °C (dec.)(lit.)
alpha	72.5 º (c=2, H2O, 5hrs.)
refractive index	72 ° (C=1, H2O)
storage temp.	2-8°C
solubility	H₂O: 0.1 g/mL, clear, colorless
form	crystalline
color	White
Water Solubility	soluble
Merck	14,4458
BRN	4157370
Stability:	Stable. Incompatible with strong oxidizing agents. Combustible.
InChI	InChI=1/C6H13NO5.ClH/c7-3-5(10)4(9)2(1-8)12-6(3)11;/h2-6,8-11H,1,7H2;1H/t2-,3-,4-,5-,6?;/s3
InChIKey	QKPLRMLTKYXDST-LPRXMDNASA-N
SMILES	[C@H]1(CO)OC([C@H](N)[C@@H](O)[C@@H]1O)O.Cl \|&1:0,5,7,9,r\|
LogP	-2.375 (est)
CAS DataBase Reference	66-84-2(CAS DataBase Reference)
EPA Substance Registry System	D-Glucose, 2-amino-2-deoxy-, hydrochloride (66-84-2)

Safety Information

Hazard Codes	F,Xi,Xn
Risk Statements	21-36/38-46-62-63
Safety Statements	24/25-53-36/37-26-25
WGK Germany	2
RTECS	LZ6665000
F	3-10
Hazard Note	Highly Flammable
TSCA	Yes
HS Code	29329985

Product Pictures

Shop China Most Professional Factory Supply High Qulity Zinc lactate CAS 16039-53-5-Detailed Image 2

About Our Group

Since 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture high quality raw materials and refined ingredients which is widely used at different industries areas like Pharm & chemicals industry, functional active ingredients industry, nutritional Ingredients industry, health care products industry, cosmetics industry, pharmaceutical and refined food, feed, oil industry, natural plant ingredients industries, agriculture industry etcs to provide top quality of GMP standards products.

All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, agriculture raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China.

Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research. Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates.

With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products. Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people.

We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.

We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

Our Factories Production Lines

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Our Factories R&D ability

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Our Factories warehouse 52000㎡

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Sales Team

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ECHEMI Editorial Reference

Cholecalciferol(Vitamin D3) is a naturally occuring form of vitamin D; Reported that upon metabolic activation, Cholecalciferol induces cell differentiation and prevents proliferation of cancer cells. IC50 value:Target: Vitamin D acts through a receptor that is a member of the ligand-dependent transcription factor superfamily. Modulates the proliferation and differentiation of both normal and cancer cells. Has antiproliferative and antimetastatic effects on breast, colon, and prostate ca
Vitamin d3 appears as fine colorless crystals. Water insoluble. (NTP, 1992)|Vitamin d3 emulsifiable is a cream colored powder. Insoluble in water. (NTP, 1992)|Solid
Vitamin d3 appears as fine colorless crystals. Water insoluble. (NTP, 1992)|Vitamin d3 emulsifiable is a cream colored powder. Insoluble in water. (NTP, 1992)|Calciol is a hydroxy seco-steroid that is (5Z,7E)-9,10-secocholesta-5,7,10(19)-triene in which the pro-S hydrogen at position 3 has been replaced by a hydroxy group. It is the inactive form of vitamin D3, being hydroxylated in the liver to calcidiol (25-hydroxyvitamin D3), which is then further hydroxylated in the kidney to give calcitriol (1,25-dihydroxyvitamin D3), the active hormone. It has a role as a human metabolite and a geroprotector. It is a seco-cholestane, a hydroxy seco-steroid, a member of D3 vitamins, a secondary alcohol and a steroid hormone.|Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight. Both the endogenous form of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin D3 (cholecalciferol), and the plant-derived form, vitamin D2 (ergocalciferol), are considered the main forms of vitamin d and are found in various types of food for daily intake. Structurally, ergocalciferol differs from cholecalciferol in that it possesses a double bond between C22 and C23 and has an additional methyl group at C24. Finally, ergocalciferol is pharmacologically less potent than cholecalciferol, which makes vitamin D3 the preferred agent for medical use. Appropriate levels of vitamin D must be upheld in the body in order to maintain calcium and phosphorus levels in a healthy physiologic range to sustain a variety of metabolic functions, transcription regulation, and bone metabolism. However, studies are also ongoing to determine whether or not cholecalciferol may also play certain roles in cancer, autoimmune disorders, cardiovascular disease, and other medical conditions that may be associated with vitamin D deficiency.|Vitamin D is a fat soluble vitamin important in the regulation of calcium metabolism and bone health and deficiency of which cause rickets, a disease marked by lack of mineralization of bone. Conventional doses of vitamin D are well tolerated without appreciable adverse effects. High doses of vitamin D can be toxic, leading to a constellation of signs and symptoms but not liver injury or jaundice.|Cholecalciferol is a steroid hormone produced in the skin when exposed to ultraviolet light or obtained from dietary sources. The active form of cholecalciferol, 1,25-dihydroxycholecalciferol (calcitriol) plays an important role in maintaining blood calcium and phosphorus levels and mineralization of bone. The activated form of cholecalciferol binds to vitamin D receptors and modulates gene expression. This leads to an increase in serum calcium concentrations by increasing intestinal absorption of phosphorus and calcium, promoting distal renal tubular reabsorption of calcium and increasing osteoclastic resorption.|Derivative of 7-dehydroxycholesterol formed by ULTRAVIOLET RAYS breaking of the C9-C10 bond. It differs from ERGOCALCIFEROL in having a single bond between C22 and C23 and lacking a methyl group at C24.

Certificates

Basic Info

Product Name:

Vitamin D3

Other Name:

Cyclohexanol,3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R)-1,5-dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-,(1S,3Z)-;Cholecalciferol;9,10-Secocholesta-5,7,10(19)-trien-3-ol,(3β,5Z,7E)-;(1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R)-1,5-Dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylenecyclohexanol;Delsterol;Deparal;Oleovitamin D3;Ricketon;Trivitan;D3-Vigantol;Vitamin D3;9,10-Secocholesta-5,7,10(19)-trien-3β-ol;Vitinc Dan-Dee-3;Vigorsan;Colecalciferol;Calciol;Quintox;Vi-De3;Arachitol;Granuvit D3;Videkhol;FeraCol;Devaron;NSC 375571;Dry Vitamin D3 100CWS/AM;Lutavit D;Riken D3 Oil 20;Duphafral D3 1000;Ekostop D3;Calcirol;Oleovit D3;UVEDOSE;Riken D3 Oil 100;Decristol;Minisun;Vigantoletten;High-D 2X;Plivit D3;Aquadetrim;Vitamin D3 S 50t;Devikap;OsteVit D;Vigantol;Rovimix D3 500;CapsuDar D3 100E;8024-19-9;8050-67-7

CAS No.:

67-97-0

Molecular Formula:

C27H44O

InChIKeys:

InChIKey=QYSXJUFSXHHAJI-YRZJJWOYSA-N

Molecular Weight:

384.64

Exact Mass:

384.64

BRN:

2339331

EC Number:

200-673-2

UN Number:

2811

DSSTox ID:

DTXSID1026295

NCI Thesaurus Code:

C48194

Color/Form:

Fine needles from dilute acetone|WHITE CRYSTALS|Colorless crystals

ATC Code:

M05BB03|A11CC05|A - Alimentary tract and metabolism

HScode:

2936240000

Categories:

Vitamins and Minerals Medicines

Characteristics

PSA:

20.2

XLogP3:

10.2 (est)

Appearance:

Vitamin d3 appears as fine colorless crystals. Water insoluble. (NTP, 1992)

Density:

0.939 g/cm³

Melting Point:

84-85 °C

Boiling Point:

496.4±24.0 °C at 760 mmHg

Flash Point:

14 °C

Refractive Index:

1.523

Water Solubility:

In water, 1.3X10-5 mg/L at 25 deg C (est)

Storage Conditions:

2-8°C

Vapor Pressure:

2.0 x l0 -6 Pa (20 °C, est.)

Toxicity:

LD50 oral in rat: 42mg/kg

Specific rotation:

105 º (c=0.8, EtOH 25 ºC)

Odor:

ODORLESS

Henrys Law Constant:

Henry's Law constant = 2.3X10-4 atm-cu m/mole at 25 °C (est)

Experimental Properties:

Oxidized and inactivated by moist air within a few days|Hydroxyl radical reaction rate constant = 2.7X10-10 cu cm/molec-sec at 25 °C (est)

Air and Water Reactions:

Sensitive to moisture, air and light. (NTP, 1992). Water insoluble.

Reactive Group:

Alcohols and Polyols

Reactivity Profile:

VITAMIN D3 may react vigorously with strong oxidizing agents. May react exothermically with reducing agents to release hydrogen gas.

See More Vitamin D3 Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 2, Oral

Acute toxicity - Category 2, Dermal

Acute toxicity - Category 2, Inhalation

Specific target organ toxicity â repeated exposure, Category 1

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H300 Fatal if swallowed H310 Fatal in contact with skin H330 Fatal if inhaled H372 Causes damage to organs through prolonged or repeated exposure
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P262 Do not get in eyes, on skin, or on clothing. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P260 Do not breathe dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area. P284 [In case of inadequate ventilation] wear respiratory protection.
Response	P301+P316 IF SWALLOWED: Get emergency medical help immediately. P321 Specific treatment (see ... on this label). P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P316 Get emergency medical help immediately. P361+P364 Take off immediately all contaminated clothing and wash it before reuse. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P320 Specific treatment is urgent (see ... on this label). P319 Get medical help if you feel unwell.
Storage	P405 Store locked up. P403+P233 Store in a well-ventilated place. Keep container tightly closed.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Vitamin D3 Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Biochemicals Ingredients,Vitamin Amino Acid Ingredients,Cosmestic Ingredients,Pharma Chemicals,Organic Fine Chemicals,Food Nutrient Ingredients

Location:
National Aerospace Economic & Technical Development Zone,Chang'an,Xi'an,China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
5 days

Total Annual Revenue:
$10 million-$25 million

Total Employees:
Above 1000

Year of Establishment:
2014

Company Certificates
- Level A of Tax Credit Registration Assessment by Government
- Good Product Quality Management Certificate of Shanxi Province,China
- Company Trade Union Qualification Certificate
- Excellent Group Enterprise of Quality and credit in Shaanxi ProvinceChina
- AAA TOP Credit Excellent Group Enterprise of Shanxi Province,China
- FDA
24 Hours Team Service
Email
info@leader-biogroup.com
Hot Line
+86-029-68895030
+86-029-68569961
+86-029-68569962
Fax
+86-029-68895030

Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories Base with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world.
- Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.
  
  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.
  
  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.
  
  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.
- Process Capability : It has more than 100 sets of multi-functional reaction reactors, such as 100l~6300l enamel, stainless steel, Hastelloy, etc. It can realize Grignard, coupling, bromination, Wittig reaction and other conventional reactions. There are microchannel reactor workshops, which can realize continuous production, energy conservation and emission reduction. It can realize high pressure, high vacuum rectification, ultra-low temperature (-80 ℃ ~-100 ℃), ultra-high temperature (300 ℃ ~400 ℃) and other special reactions. It can realize the customization and processing of customers' products.
Factory Overview

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GROUP HONOR
Honor Name: Level A of Tax Credit Registration Assessment
Issued By:National Administration of Taxation & Shaanxi Tax Bureau
Authorised Date:2018-09-16
Description: National Administration of Taxation & Shaanxi Tax Bureau

Honor Name: AAA TOP Credit Excellent Group Enterprise of Shanxi Province,China
Issued By:China Association of Shaanxi product Quality management Center
Authorised Date:2018-12-31
Description:AAA TOP Credit Excellent Group Enterprise of Shanxi Province,China

Honor Name:Excellent Group Enterprise of Quality and credit in Shaanxi ProvinceChina
Issued By: China Association of Shaanxi product Quality management Center
Authorised Date:2018-12-31
Description: Excellent Group Enterprise of Quality and Integrity in Shaanxi Province,China

Honor Name: Products Patent Certificates

Inquiry History

59 Inquiries

Country	Product	Purchase Quantity	Date Posted
Italy	Food additive Vitamin D3 CAS 67-97-0 99% Fine powders HHD Wuhan hhd	75 KG	Oct 12, 2023
New Zealand	Factory Supply Vitamin D3 / Cholecalciferol d6 / CAS 67-97-0 / Cholecalciferol d6 99% White Powder C27H44O	1 KG	Oct 11, 2023
India	VITAMIN D3 IP 40 MIU	50.00 G	Nov 7, 2025
Russia	Vitamin D3 powder, Vitamin K2 powder	10 KG	Jan 27, 2025
Pakistan	Vitamin D3	20 KG	Jul 24, 2026
India	Cholecalciferol (Vitamin D3)	5 G	Jul 12, 2026
United States	Vitamin D3	10 MG	May 30, 2026
Germany	Cholecalciferol	200 G	Apr 10, 2026
Germany	Vitamin D3	200 G	Apr 9, 2026
Egypt	Vit D	25 KG	Dec 16, 2025
Slovakia	Vitamin D3	100 KG	Nov 7, 2025
United States	Vitamin D3	10 KG	Jul 29, 2025
South Korea	Cholecalciferol Vitamin D3	200 KG	Apr 29, 2025
Turkey	KOLEKALSIFEROL ( VİT D3)	5.00 KG	Apr 16, 2025
India	Vitamin d3	10 G	Jan 26, 2025
South Korea	Vitamin D3	500 KG	Jan 24, 2025
India	Vitamin D3	500 KG	Nov 14, 2024
Pakistan	VITAMIN D3	5 KG	Nov 12, 2024
Bangladesh	Colecalciferol	50 KG	Aug 15, 2024
New Zealand	Cholecalciferol (Vitamin D3)	100 KG	May 10, 2024

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China Most Professional Factory Supply High Qulity Cholecalciferol(Vitamin D3) CAS 67-97-0

Product Description

Seller Information

Inquiry History

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

Factory Logistics Departments

GROUP HONOR

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Email	info@leader-biogroup.com
Hot Line	+86-029-68895030
	+86-029-68569961
	+86-029-68569962
Fax	+86-029-68895030