4-AMINO-2-(2,6-DIOXOPIPERIDIN-3-YL)ISOINDOLINE-1,3-DIONE
2 Inquiries
19171-19-8
Industrial Grade
99%
25kg/Cardboard Drum
2026-09-26
Di-tert-Butyl malonate
-
Product Description
-
Seller Information
-
Inquiry History
-
DescriptionCHEMLYTE SOLUTIONS CO.,LTD, with approximately 871206 visits to its shop, is a reputable Manufactory that has been providing 4-AMINO-2-(2,6-DIOXOPIPERIDIN-3-YL)ISOINDOLINE-1,3-DIONE products for 3 years on ECHEMI.ECHEMI Editorial ReferenceYellow SolidChEBI: An aromatic amine that is thalidomide substituted at position 4 on the isoindole ring system by an amino group. Used for the treatment of multiple myeloma in patients who failed to respond to previous therapies.Pomalidomide inhibits LPS-induced TNF-α release with IC50 of 13 nM in PBMCs. In February 2013, the US FDA approved pomalidomide (also known as CC4047) for the treatment of multiple myeloma (MM) in patients with disease progression after receiving other cancer therapeut
Pomalidomide is an aromatic amine that is thalidomide substituted at position 4 on the isoindole ring system by an amino group. Used for the treatment of multiple myeloma in patients who failed to respond to previous therapies. It has a role as an antineoplastic agent, an immunomodulator and an angiogenesis inhibitor. It is a dicarboximide, a member of isoindoles, a member of piperidones and an aromatic amine. It derives from a thalidomide.|Pomalidomide, an analogue of thalidomide, is an immunomodulatory antineoplastic agent. FDA approved on February 8, 2013.|Pomalidomide is an immunomodulatory and antineoplastic agent that is used in the therapy of multiple myeloma. Pomalidomide, like the structurally related agents thalidomide and lenalidomide, is associated with a low rate of serum aminotransferase elevations during therapy and has been implicated in causing rare instances of clinically apparent liver injury which can be severe.|Thalidomide and its analogue lenalidomide are immunomodulatory and antineoplastic agents that are used in the therapy of multiple myeloma. Both agents are associated with a low rate of serum aminotransferase elevations during therapy and both have been implicated in causing rare instances of clinically apparent liver injury which can be severe.Basic Info-
Product Name:
Pomalidomide
Other Name:1H-Isoindole-1,3(2H)-dione,4-amino-2-(2,6-dioxo-3-piperidinyl)-;Phthalimide,3-amino-N-(2,6-dioxo-3-piperidyl)-;4-Amino-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione;4-Amino-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione;CC 4047;Actimid;4-Amino-2-(2,6-dioxo-3-piperidinyl)isoindole-1,3-dione;Pomalidomide;4-Amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione;2-(2,6-Dioxopiperidin-3-yl)-4-amino-isoindole-1,3-dione;4-Amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione;Pomalyst;Imnovid;443912-23-0;443919-33-3
CAS No.:19171-19-8
Molecular Formula:C13H11N3O4
InChIKeys:InChIKey=UVSMNLNDYGZFPF-UHFFFAOYSA-N
Molecular Weight:273.24
Exact Mass:273.24
EC Number:1592732-453-0
Color/Form:Solid yellow powder
ATC Code:L04AX06|L - Antineoplastic and immunomodulating agents
HScode:29251900
Categories:
Characteristics-
PSA:
110
XLogP3:0.2
Appearance:yellow
Density:1.570±0.06 g/cm3(Predicted)
Melting Point:318.5 - 320.5°
Boiling Point:582.9±45.0 °C(Predicted)
Flash Point:306.3±28.7 °C
Refractive Index:1.691
Water Solubility:DMSO: ≥14mg/mL
Storage Conditions:2-8°C
Vapor Pressure:7.54X10-16 mm Hg at 25 deg C (est)
Dissociation Constants:pKa1 = 1.56 (aromatic amine); pKa2 = 11.59 (secondary amide) (est)
Experimental Properties:Henry's Law contant = 4.56X10-20 atm-cu m/mol at 25 °C (est)
Hazard IdentificationClassification of the substance or mixture
Reproductive toxicity, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H361 Suspected of damaging fertility or the unborn child
Precautionary statement(s) Prevention P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
-
-
Seller Information
-
Business Type:
Manufactory
-
Main Products:
Di-tert-Butyl malonate
-
Location:
CHEMLYTE SOLUTIONS CO.,LTD
-
Payment Terms:
O/A
-
Average lead Time:
20
-
Total Annual Revenue:
$10 million-$25 million
-
Total Employees:
11-50
-
Year of Establishment:
2019
-
-
Inquiry History2 Inquiries
Country Product Purchase Quantity Date Posted 
Pakistan
Pomalidomide
1 KG May 27, 2025
Pakistan
Pomalidomide
1 KG May 26, 2025 Post an enquiry for this product