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China Most Professional Factory Supply High Qulity HEDP CAS 2809-21-4

Name: China Most Professional Factory Supply High Qulity HEDP CAS 2809-21-4
Brand: Leader
SKU: pr2312101290
Price: 1 USD
Availability: InStock

GMP HALAL KOSHER ISO FDA TDS 26 Inquiries

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CAS No.:

2809-21-4

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Shanghai

Brand:

Leader

Packaging:

25KG/Drum

Sample Available:

Yes

Price valid (until):

2024-01-10

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LEADER BIOCHEMICAL GROUP

Company Type:

Manufactory

Location:

China

Payment Terms:

TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

5 days

Qualification:

Main Products:

Biochemicals Ingredients,Vitamin Amino Acid Ingredients,Cosmestic Ingredients,Pharma Chemicals,Organic Fine Chemicals,Food Nutrient Ingredients

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Product Description
Seller Information
Inquiry History

Description

About Product Technical Details

1-Hydroxyethylidene-1,1-diphosphonic acid Chemical Properties

Melting point	198~199℃
Boiling point	578.8±60.0 °C(Predicted)
density	1.45 (60% aq.)
vapor pressure	0Pa at 25℃
storage temp.	Sealed in dry,Room Temperature
solubility	Methanol (Slightly), Water (Slightly)
form	Powder
pka	1.35, 2.87, 7.03, 11.3(at 25℃)
color	white
PH	pH (1.7→100, 25℃) : 1.3～1.8
Water Solubility	Soluble in water.
Merck	14,3863
BRN	1789291
Stability:	Stable. Incompatible with strong oxidizing agents.
InChIKey	DBVJJBKOTRCVKF-UHFFFAOYSA-N
LogP	-3.5
CAS DataBase Reference	2809-21-4(CAS DataBase Reference)
EPA Substance Registry System	Etidronic acid (2809-21-4)

Safety Information

Hazard Codes	Xi,Xn
Risk Statements	37/38-41-22
Safety Statements	26-39
RIDADR	UN 3265
WGK Germany	2
RTECS	SZ8562100
F	10
TSCA	Yes
HazardClass	8
PackingGroup	II
HS Code	29319090

D-Glucosamine hydrochloride Chemical Properties

Melting point	190-194 °C (dec.)(lit.)
alpha	72.5 º (c=2, H2O, 5hrs.)
refractive index	72 ° (C=1, H2O)
storage temp.	2-8°C
solubility	H₂O: 0.1 g/mL, clear, colorless
form	crystalline
color	White
Water Solubility	soluble
Merck	14,4458
BRN	4157370
Stability:	Stable. Incompatible with strong oxidizing agents. Combustible.
InChI	InChI=1/C6H13NO5.ClH/c7-3-5(10)4(9)2(1-8)12-6(3)11;/h2-6,8-11H,1,7H2;1H/t2-,3-,4-,5-,6?;/s3
InChIKey	QKPLRMLTKYXDST-LPRXMDNASA-N
SMILES	[C@H]1(CO)OC([C@H](N)[C@@H](O)[C@@H]1O)O.Cl \|&1:0,5,7,9,r\|
LogP	-2.375 (est)
CAS DataBase Reference	66-84-2(CAS DataBase Reference)
EPA Substance Registry System	D-Glucose, 2-amino-2-deoxy-, hydrochloride (66-84-2)

Safety Information

Product Pictures

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About Our Group

Since 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture high quality raw materials and refined ingredients which is widely used at different industries areas like Pharm & chemicals industry, functional active ingredients industry, nutritional Ingredients industry, health care products industry, cosmetics industry, pharmaceutical and refined food, feed, oil industry, natural plant ingredients industries, agriculture industry etcs to provide top quality of GMP standards products.

All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, agriculture raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China.

Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research. Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates.

With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products. Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people.

We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.

We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

Our Factories Production Lines

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Our Factories warehouse 52000㎡

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Sales Team

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ECHEMI Editorial Reference

Etidronic acid is a bisphosphonate used in detergents, water treatment, cosmetics and pharmaceutical treatment.Target: OthersEtidronic Acid is a chelating agent and may be added to bind to or counter the effects of substances such as arsenic, iron, or other metal ions that can occur in the presence of some soaps. Etidronic acid also acts to retard oxidation of fatty acids. For clarification, a chelator, or chelating agent is a binding component added to many cosmetics, beauty products, a
Liquid|Solid
Etidronic acid is a 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces. It has a role as a bone density conservation agent, a chelator and an antineoplastic agent. It is a conjugate acid of an etidronic acid(2-).|Etidronic acid is a first generation bisphosphonate similar to [clodronic acid] and [tiludronic acid]. These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Etidronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate [zoledronic acid], [ibandronic acid], [minodronic acid], and [risedronic acid]. Etidronic acid was granted FDA approval on 1 September 1977.|Etidronic acid is a Bisphosphonate.|Etidronic Acid is as a member of the family of drugs known as bisphosphonates, etidronate differs from endogenous pyrophosphate in its resistance to enzymatic hydrolysis. This agent adsorbs to hydroxyapatite cells and reduces the number of osteoclasts, thereby inhibiting abnormal bone resorption. Etidronate may also directly stimulate bone formation by osteoblasts. (NCI)|A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.

Certificates

Basic Info

Product Name:

(1-Hydroxyethylidene)-1,1-diphosphonic acid

Other Name:

Phosphonic acid,P,P′-(1-hydroxyethylidene)bis-;Phosphonic acid,(1-hydroxyethylidene)di-;Phosphonic acid,(1-hydroxyethylidene)bis-;P,P′-(1-Hydroxyethylidene)bis[phosphonic acid];1-Hydroxyethane-1,1-diphosphonic acid;Etidronic acid;Ethane-1-hydroxy-1,1-diphosphonic acid;(1-Hydroxyethylidene)diphosphonic acid;Dequest Z 010;(1-Hydroxyethylidene)-1,1-diphosphonic acid;1000SL;Oxyethylidenediphosphonic acid;Hydroxyethanediphosphonic acid;1-Hydroxyethanediphosphonic acid;EHDP;Dequest 2010;1-Hydroxy-1,1-diphosphonoethane;Dequest 2015;HEDP;(1-Hydroxyethylidene)bisphosphonic acid;Turpinal SL;1-Hydroxyethane-1,1-bisphosphonic acid;Ferrofos 510;(1-Hydroxyethylidene)-1,1-bis(phosphonic acid);Feliox 115;Wayplex;Xydiphone;Lonza 106;Tecquest 360;OEDF;OEDP;Xidiphone;Ksidifon;Defloc EH 06;Mayoquest 1500;HDEPA;Turpinal SLR;Masquol P 210;Terpil SL;RP 61;Cublen K 60;Dequest 2010CS;1-Hydroxyethane-1,1-diyldiphosphonic acid;Sone 16;Dequest 16;Briquest ADPA 60A;Acetodiphosphonic acid;Unihib 106;Anti Cal 5;Sequion 10H;1-Hydroxyethylidene-1,1′-diphosphonic acid;Mascol P 210;NSC 227995;Belclene 660;Feliox CY 115;Chelate 101;OEDFK;1-Hydroxyethylidene-1,1-diphosphoric acid;Briquest ADPA-A;Acidum etidronicum;Ethydronate;Ethidronate;Etidronate;Dequest 2010LA;Feliox 115A;Xidifon;Kochtreat 75;Chelest PH 210L;Dequest D 2010;Dequest 2010R;1-Hydroxyethylidene-1,1-diphoshonic acid;Aquacid 105EX;Aquacid 105CG;51888-66-5;66216-98-6;83047-25-0;85188-80-3;85985-26-8;86159-18-4;100511-44-2;103736-66-9;106908-76-3;129130-42-3;138360-84-6;192526-55-9;303177-33-5;853028-38-3

CAS No.:

2809-21-4

UN No.:

3265

Molecular Formula:

C2H8O7P2

InChIKeys:

InChIKey=DBVJJBKOTRCVKF-UHFFFAOYSA-N

Molecular Weight:

206.02800

Exact Mass:

206.03

EC Number:

220-552-8

UNII:

M2F465ROXU

NSC Number:

227995

DSSTox ID:

DTXSID6023028

NCI Thesaurus Code:

C1332

ATC Code:

M - Musculo-skeletal system

HScode:

2931900090

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

154.91000

XLogP3:

-3.7

Appearance:

Liquid

Density:

1.45 (60% aq.)

Melting Point:

155 °C (decomp)

Boiling Point:

578.8ºC at 760 mmHg

Flash Point:

303.8ºC

Refractive Index:

1.586

Water Solubility:

Soluble in water.

Vapor Pressure:

8.34E-16mmHg at 25°C

Toxicity:

LD50 oral in mouse: 1800mg/kg

See More (1-Hydroxyethylidene)-1,1-diphosphonic acid Properties 

Hazard Identification

Classification of the substance or mixture

Corrosive to metals, Category 1

Acute toxicity - Category 4, Oral

Serious eye damage, Category 1

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H290 May be corrosive to metals H302 Harmful if swallowed H318 Causes serious eye damage
Prevention	P234 Keep only in original packaging. P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P390 Absorb spillage to prevent material damage. P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P317 Get medical help.
Storage	P406 Store in a corrosion resistant/...container with a resistant inner liner.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More (1-Hydroxyethylidene)-1,1-diphosphonic acid Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Biochemicals Ingredients,Vitamin Amino Acid Ingredients,Cosmestic Ingredients,Pharma Chemicals,Organic Fine Chemicals,Food Nutrient Ingredients

Location:
National Aerospace Economic & Technical Development Zone,Chang'an,Xi'an,China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
5 days

Total Annual Revenue:
$10 million-$25 million

Total Employees:
Above 1000

Year of Establishment:
2014

Company Certificates
- Level A of Tax Credit Registration Assessment by Government
- Good Product Quality Management Certificate of Shanxi Province,China
- Company Trade Union Qualification Certificate
- Excellent Group Enterprise of Quality and credit in Shaanxi ProvinceChina
- AAA TOP Credit Excellent Group Enterprise of Shanxi Province,China
- FDA
24 Hours Team Service
Email
info@leader-biogroup.com
Hot Line
+86-029-68895030
+86-029-68569961
+86-029-68569962
Fax
+86-029-68895030

Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories Base with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world.
- Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.
  
  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.
  
  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.
  
  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.
- Process Capability : It has more than 100 sets of multi-functional reaction reactors, such as 100l~6300l enamel, stainless steel, Hastelloy, etc. It can realize Grignard, coupling, bromination, Wittig reaction and other conventional reactions. There are microchannel reactor workshops, which can realize continuous production, energy conservation and emission reduction. It can realize high pressure, high vacuum rectification, ultra-low temperature (-80 ℃ ~-100 ℃), ultra-high temperature (300 ℃ ~400 ℃) and other special reactions. It can realize the customization and processing of customers' products.
Factory Overview

   Factory Production Lines

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GROUP HONOR
Honor Name: Level A of Tax Credit Registration Assessment
Issued By:National Administration of Taxation & Shaanxi Tax Bureau
Authorised Date:2018-09-16
Description: National Administration of Taxation & Shaanxi Tax Bureau

Honor Name: AAA TOP Credit Excellent Group Enterprise of Shanxi Province,China
Issued By:China Association of Shaanxi product Quality management Center
Authorised Date:2018-12-31
Description:AAA TOP Credit Excellent Group Enterprise of Shanxi Province,China

Honor Name:Excellent Group Enterprise of Quality and credit in Shaanxi ProvinceChina
Issued By: China Association of Shaanxi product Quality management Center
Authorised Date:2018-12-31
Description: Excellent Group Enterprise of Quality and Integrity in Shaanxi Province,China

Honor Name: Products Patent Certificates

Inquiry History

26 Inquiries

Country	Product	Purchase Quantity	Date Posted
Egypt	1-Hydroxy Ethylidene-1,1-Diphosphonic Acid (HEDP)	1 20' Fcl	Nov 15, 2025
Russia	Etidronic acid( HEDP)	1 20' Fcl	Feb 10, 2025
Uzbekistan	HEDP	100 KG	Jun 13, 2025
United Arab Emirates	Hydroxyethylidene Diphosphonic Acid - HEDP 60%	20.00 MT	Jun 8, 2026
Egypt	Hydroxyethylidene Diphosphonic Acid	1.00 KG	Apr 27, 2026
India	HEDP 60%	1 KG	Apr 14, 2026
Egypt	1-Hydroxyethylidene-1,1-diphosphonic acid	1.00 KG	Mar 25, 2026
Uzbekistan	1-Hydroxyethane-1,1-diphosphonic Acid	60 MT	Feb 26, 2026
Turkey	HEDP 60%	1 20' Fcl	Feb 9, 2026
Egypt	Hydroxyethylidene diphosphonic acid	1.00 20' Fcl	Nov 24, 2025
Egypt	HEDP Phosphonic Acid 1-Hydroxyethylidene-1, 1-Diphosphonic Acid	1 20' Fcl	Oct 11, 2025
Egypt	Hydroxyethylidene Diphosphonic Acid	1.00 L	Oct 9, 2025
India	HEDP60	3 MT	Sep 15, 2025
India	1-Hydroxyethylidene-1, 1-Diphosphonic Acid (HEDP)	1000 TON	Aug 4, 2025
India	Etidronic acid (HEDP)	65.00 KG	Aug 1, 2025
Indonesia	Dequest 2010 LC	1 MT	Jul 31, 2025
Brazil	PHOSPHONATE - HEDP UN3265 CLAS 8	176000.00 KG	Jun 13, 2025
India	Hydroxyethylidene Diphosphonic Acid 60%	10.00 MT	Apr 23, 2025
India	1-Hydroxyethylidene-1,1-diphosphonic acid	1.00 20' Fcl	Dec 9, 2024
Vietnam	BELCLENE 660 (HEDP)	100.00 KG	Feb 27, 2024

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Product Name	Grade / Content	Price	Supplier Name	Details
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HEDP 60%	top/99	$1.1/KG EXW	Xiamen Eagle Chemical Corporation	Inquiry
1-Hydroxyethylidene-1,1-Diphosphonic Acid (HEDP ACID 60%)	/	$1000-1200/MT FOB	Evolutics International Pvt. Ltd.	Inquiry
Etidronic Acid	Tech Grade/99	$16.5/KG EXW	DAHAI BIOCHEM LTD	Inquiry

China Most Professional Factory Supply High Qulity HEDP CAS 2809-21-4

Product Description

Seller Information

Inquiry History

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

Factory Logistics Departments

GROUP HONOR

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Email	info@leader-biogroup.com
Hot Line	+86-029-68895030
	+86-029-68569961
	+86-029-68569962
Fax	+86-029-68895030