8-[(E)-2-(3,4-dimethoxyphenyl)ethenyl]-1,3-diethyl-7-methyl-purine-2,6 -dione, CAS:155270-99-8
2 Inquiries
155270-99-8
Reagent Grade
99%
Guangzhou
BTO
kg
2029-12-31
Custom Synthetic Chemicals,Biological Stains,Pharmaceutical Intermediates,Cosmetic Grade Chemicals,Enzyme,Nucleosides
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceIn March 2013, istradefylline (also known as KW-6002) was approved in Japan for adjunctive treatment of Parkinson’s disease (PD). Istradefylline acts by antagonism of the adenosine A2A receptor, which is colocalized with dopamine D2 receptors in the striatum, to enhance dopamine D2-dependent signaling. Istradefylline is a light-sensitive compound and has been evaluated in vitro under low-light conditions to prevent isomerization of the (E)-styryl group and decompos.Basic Info
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Product Name:
Istradefylline
Other Name:1H-Purine-2,6-dione,8-[(1E)-2-(3,4-dimethoxyphenyl)ethenyl]-1,3-diethyl-3,7-dihydro-7-methyl-;1H-Purine-2,6-dione,8-[2-(3,4-dimethoxyphenyl)ethenyl]-1,3-diethyl-3,7-dihydro-7-methyl-,(E)-;8-[(1E)-2-(3,4-Dimethoxyphenyl)ethenyl]-1,3-diethyl-3,7-dihydro-7-methyl-1H-purine-2,6-dione;KW 6002;Istradefylline;Nourianz;Nouriast
CAS No.:155270-99-8
Molecular Formula:C20H24N4O4
InChIKeys:InChIKey=IQVRBWUUXZMOPW-PKNBQFBNSA-N
Molecular Weight:384.43
Exact Mass:384.43
Categories:
Characteristics-
PSA:
76.9
XLogP3:2.84
Appearance:white to beige
Density:1.24±0.1 g/cm3(Predicted)
Melting Point:191 °C
Boiling Point:601.0±65.0 °C(Predicted)
Flash Point:317.3±34.3 °C
Refractive Index:1.598
Water Solubility:DMSO: soluble5mg/mL (clear solution)
Storage Conditions:2-8°C
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 3, Oral
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Danger
Hazard statement(s) H301 Toxic if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Custom Synthetic Chemicals,Biological Stains,Pharmaceutical Intermediates,Cosmetic Grade Chemicals,Enzyme,Nucleosides
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Location:
Room 308-80, building 1, 1963 Huaguan Road, Tianhe District, Guangzhou
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,100% TT in advance
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Average lead Time:
30 days
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
51-100
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Year of Establishment:
2021
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Inquiry History2 Inquiries
Country Product Purchase Quantity Date Posted
Canada
Istradefylline
10 G Dec 6, 2023
United States
Istradefylline
1 G Oct 7, 2023 Post an enquiry for this product
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