Molsidomine API
25717-80-0
Pharmaceutical Grade
99%
Shanghai
Dideu
25kg/Drum
2024-01-11
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceMolsidomine is an orally active, long acting vasodilating drug, metabolized in the liver to the active metabolite linsidomine, which is an unstable compound that releases nitric oxide (NO) upon decay as the actual vasodilating compound.
Molsidomine is a member of the class of oxadiazoles that is 1,2,3-oxadiazole substituted by morpholin-4-yl and (ethoxycarbonyl)azanidyl groups at positions 3 and 5, respectively. It is used as a vasodilator drug for the treatment of myocardial ischemic syndrome and congestive heart failure. It has a role as a vasodilator agent, an antioxidant, a nitric oxide donor, an apoptosis inhibitor and a cardioprotective agent. It is a member of morpholines, an oxadiazole, an ethyl ester and a zwitterion.|A morpholinyl sydnone imine ethyl ester, having a nitrogen in place of the keto oxygen. It acts as NITRIC OXIDE DONORS and is a vasodilator that has been used in ANGINA PECTORIS.Basic Info-
Product Name:
Molsidomine
Other Name:1,2,3-Oxadiazolium,5-[(ethoxycarbonyl)amino]-3-(4-morpholinyl)-,inner salt;Sydnone imine,N-carboxy-3-morpholino-,ethyl ester;Sydnone imine,N-(ethoxycarbonyl)-3-(4-morpholinyl)-;N-Ethoxycarbonyl-3-morpholinosydnonimine;N-(Ethoxycarbonyl)-3-morpholinosydnone imine;Molsidomine;Morial;Corvaton;SIN 10;SIN 10 (pharmaceutical);Sydnopharm;Corraton;Morsydomine;Corvasal;Molsidolat;CAS 276;Motazomin;Coruno;Molsicor;625821-16-1;2125492-39-7
CAS No.:25717-80-0
Molecular Formula:C9H14N4O4
InChIKeys:InChIKey=XLFWDASMENKTKL-UHFFFAOYSA-N
Molecular Weight:242.23
Exact Mass:242.101501
EC Number:247-207-4
DSSTox ID:DTXSID0045171
ATC Code:C01DX12
HScode:2934999090
Categories:
Characteristics-
PSA:
87 Ų
XLogP3:-1.61
Density:1.3186 (rough estimate)
Melting Point:140.5 °C
Boiling Point:266°C
Water Solubility:0.00465 to 1.74
Storage Conditions:2-8°C
Toxicity:LD50 in male, female mice, male, female rats (mg/kg): 780, 750, 1380, 1350 s.c.; 860, 800, 830, 760 i.v.; 700, 760, 1250, 1250 i.p.; 830, 840, 1050, 1200 orally (Nakaguchi)
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst
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Location:
https://www.dideu.com/en/
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
7 days
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Total Annual Revenue:
Above $100 million
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Total Employees:
Above 1000
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Year of Establishment:
2016
Company Certificates-
ISO Certificate
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REACH
">Company Profile -
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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