Ponazuril 69004-04-2 Toltrazuril sulfone Ponazuril - Diclazuril Toltrazuril
TDS 4 Inquiries
69004-04-2
Pharmaceutical Grade
99%
/
HORLDEN
1kg/Consult ; 5kg, 25kg, customer service
Yes
2024-06-06
Chemical,Intermediate,5-amino-1mq,SLU-PP332,Tirzepatide,Peptide
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferencePonazuril, sold by the Bayer Corporation under the trade name Marquis, is a drug currently approved for the treatment of equine protozoal myeloencephalitis in horses, caused by Sarcocystis neurona.
Toltrazuril sulfone is an active metabolite of the coccidiostat toltrazuril . Toltrazuril sulfone is formed from toltrazurilviathe intermediate metabolite toltrazuril sulfoxide by cytochrome P450 (CYP) enzymes, including CYP3A. It inhibitsT. gondiitachyzoite production in African green monkey kidney cells when used at concentrations of 0.1, 1, and 5 μg/ml. Toltrazuril sulfone completely prevents infection withT. gondiitachyzoites in a mouse model of fatal toxoplasmosis when administered at doses of 10 or 20 mg/kg one day prior to, and daily for 10 days following, infection. It also reduces the number of infected mice in the same model when administered at a dose of 10 mg/kg for 11 days starting six days following infection. Formulations containing toltrazuril sulfone have been used in the treatment of equine protozoal myeloencephalitis (EPM) in horses.Certificates-
TDS
Basic Info-
Product Name:
Ponazuril
Other Name:Toltrazuril sulfone Ponazuril;1-Methyl-3-{3-methyl-4-[4-(trifluoromethylsulfonyl)phenoxy]phenyl}-1,3,5-triazine-2,4,6(1H,3H;Ponazuril;ToltrazurilSulfone;1-Methyl-3-{3-methyl-4-[4-(trifluoromethylsulfonyl)phenoxy]phenyl}-1,3,5-triazine-2,4,6(1H,3H,5H)-trione;Ponazuril [inn];Unii-jpw84as66u;1-methyl-3-[3-methyl-4-[4-(trifluoromethylsulfonyl)phenoxy]phenyl]-1,3,5-triazinane-2,4,6-trione
CAS No.:69004-04-2
Molecular Formula:C18H14F3N3O6S
InChIKeys:VBUNOIXRZNJNAD-UHFFFAOYSA-N
Molecular Weight:457.38
Exact Mass:457.38
EC Number:629-740-8
UNII:JPW84AS66U
DSSTox ID:DTXSID7048958
Color/Form:White to Off-White
Categories:
Characteristics-
PSA:
122
XLogP3:3.1
Density:1.507±0.06 g/cm3(Predicted)
Melting Point:242°
Refractive Index:1.572
PKA:6.46±0.20(Predicted)
Critical Temperature & Pressure:Refrigerator
Hazard IdentificationClassification of the substance or mixture
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word No signal word
Hazard statement(s) H411 Toxic to aquatic life with long lasting effects
Precautionary statement(s) Prevention P273 Avoid release to the environment.
Response P391 Collect spillage.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Chemical,Intermediate,5-amino-1mq,SLU-PP332,Tirzepatide,Peptide
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Location:
9th Floor, Room 923, Building 3, Shiyuan Daguan, Xingtai 1st Street, Chanba Ecological District, Xi'an City, Shaanxi Province
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Payment Terms:
100% TT in advance
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Average lead Time:
7 days
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
11-50
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Year of Establishment:
2015
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Inquiry History4 Inquiries
Country Product Purchase Quantity Date Posted 
United States
Ponazuril
200 G May 8, 2024
United States
Ponazuril
2 KG Mar 14, 2026
United States
Ponzuril
5 KG Mar 16, 2026
United States
Ponazuril
1 KG Oct 1, 2024 Post an enquiry for this product
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