Amino acid,intermediates
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceCanertinib (CI-1033;PD-183805) is a potent and irreversible EGFR inhibitor; inhibits cellular EGFR and ErbB2 autophosphorylation with IC50s of 7.4 and 9 nM.
Canertinib is a quinazoline compound having a 3-chloro-4-fluoroanilino group at the 4-position, a propenamido group at the 6-position, and a 3-morpholinopropoxy group at the 7-position. It has a role as a tyrosine kinase inhibitor and an antineoplastic agent. It is a member of quinazolines, an organofluorine compound, a member of morpholines and a member of monochlorobenzenes.|Canertinib is a pan-erbB tyrosine kinase inhibitor which work against esophageal squamous cell carcinoma in vitro and in vivo. Canertinib treatment significantly affects tumour metabolism, proliferation and hypoxia as determined by PET.Basic Info-
Product Name:
Canertinib
Other Name:2-Propenamide,N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-quinazolinyl]-;N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-quinazolinyl]-2-propenamide;Canertinib;N-[4-(3-Chloro-4-fluorophenylamino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]acrylamide;Cl 1033;4-[(3-Chloro-4-fluorophenyl)amino]-7-[3-(morpholin-4-yl)propyloxy]-6-[(vinylcarbonyl)amino]quinazoline
CAS No.:267243-28-7
Molecular Formula:C24H25ClFN5O3
InChIKeys:InChIKey=OMZCMEYTWSXEPZ-UHFFFAOYSA-N
Molecular Weight:485.944
Exact Mass:485.94
EC Number:1308068-626-2
UNII:C78W1K5ASF
DSSTox ID:DTXSID8048943
Categories:
Characteristics-
PSA:
88.6
XLogP3:3.9
Appearance:white or similar to white crystalline powder
Density:1.4±0.1 g/cm3
Melting Point:188-190°
Boiling Point:691.0±55.0°C at 760 mmHg
Flash Point:371.7±31.5 °C
Refractive Index:1.650
Vapor Pressure:2.86E-18mmHg at 25°C
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Amino acid,intermediates
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Location:
Room 403, 3-1, 4-1 (Industrial Design Center), No. 18, Wujiang Road, Wulidian Street, Jiangbei District, Chongqing City, China.
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
2 days
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Total Annual Revenue:
$10 million-$25 million
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Total Employees:
11-50
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Year of Establishment:
2017
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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