 Home > Biochemical Engineering > Plant Extracts > Phorbol 12-myristate 13-acetate for Sale > China Most Professional Factory Supply High Qulity Phorbol-12-Myristate-13-Acetate CAS 16561-29-8

China Most Professional Factory Supply High Qulity Phorbol-12-Myristate-13-Acetate CAS 16561-29-8 buy - large image1

China Most Professional Factory Supply High Qulity Phorbol-12-Myristate-13-Acetate CAS 16561-29-8 buy - image1

China Most Professional Factory Supply High Qulity Phorbol-12-Myristate-13-Acetate CAS 16561-29-8 buy - image2

China Most Professional Factory Supply High Qulity Phorbol-12-Myristate-13-Acetate CAS 16561-29-8 buy - image3

China Most Professional Factory Supply High Qulity Phorbol-12-Myristate-13-Acetate CAS 16561-29-8 buy - image4

China Most Professional Factory Supply High Qulity Phorbol-12-Myristate-13-Acetate CAS 16561-29-8

Name: China Most Professional Factory Supply High Qulity Phorbol-12-Myristate-13-Acetate CAS 16561-29-8
Brand: Leader
SKU: pr2312261059
Price: 1 USD
Availability: InStock

GMP HALAL KOSHER ISO FDA TDS

Unit Price: Get Latest Price 

CAS No.:

16561-29-8

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Shanghai

Brand:

Leader

Packaging:

25KG/Drum

Price valid (until):

2024-01-26

Contact Supplier

 Chat Now

LEADER BIOCHEMICAL GROUP

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Biochemicals Ingredients,Vitamin Amino Acid Ingredients,Cosmestic Ingredients,Pharma Chemicals,Organic Fine Chemicals,Food Nutrient Ingredients

 Visit Store

Product Description
Seller Information

Description

About Product Technical Details

PHORBOL 12-MYRISTATE 13-ACETATE Chemical Properties

Melting point	65-79oC
Boiling point	571.87°C (rough estimate)
density	1.17±0.1 g/cm3 (20 ºC 760 Torr)
refractive index	1.4900 (estimate)
storage temp.	-20°C
solubility	DMSO: DMSO solutions can be stored dark at −20°C for at least six months.soluble
form	Fine Crystalline Powder
pka	11.19±0.70(Predicted)
color	Off-white to light yellow
Sensitive	Light Sensitive
BRN	2407201
Stability:	Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
InChIKey	PHEDXBVPIONUQT-RGYGYFBISA-N
CAS DataBase Reference	16561-29-8(CAS DataBase Reference)
EPA Substance Registry System	12-O-Tetradecanoylphorbol 13-acetate (16561-29-8)

Safety Information

Hazard Codes	Xi
Risk Statements	38-36/37/38
Safety Statements	36/37-26
RIDADR	2928
WGK Germany	3
RTECS	QH4377000
F	8-10
HazardClass	6.1(a)
PackingGroup	II
HS Code	29153900

Emodin-3-methyl ether Chemical Properties

Melting point	196-206°C
Boiling point	560.5±50.0 °C(Predicted)
density	1.448±0.06 g/cm3(Predicted)
storage temp.	-20°C Freezer, Under Inert Atmosphere
solubility	Chloroform (Slightly, Heated), Ethyl Acetate (Slightly, Heated), Methanol (Slightly)
pka	6.23±0.20(Predicted)
form	neat
color	Yellow to Dark Yellow to Dark Orange
BRN	6770499
Stability:	Hygroscopic
InChIKey	FFWOKTFYGVYKIR-UHFFFAOYSA-N
LogP	5.078 (est)
CAS DataBase Reference	521-61-9(CAS DataBase Reference)

D-Glucosamine hydrochloride Chemical Properties

Melting point	190-194 °C (dec.)(lit.)
alpha	72.5 º (c=2, H2O, 5hrs.)
refractive index	72 ° (C=1, H2O)
storage temp.	2-8°C
solubility	H₂O: 0.1 g/mL, clear, colorless
form	crystalline
color	White
Water Solubility	soluble
Merck	14,4458
BRN	4157370
Stability:	Stable. Incompatible with strong oxidizing agents. Combustible.
InChI	InChI=1/C6H13NO5.ClH/c7-3-5(10)4(9)2(1-8)12-6(3)11;/h2-6,8-11H,1,7H2;1H/t2-,3-,4-,5-,6?;/s3
InChIKey	QKPLRMLTKYXDST-LPRXMDNASA-N
SMILES	[C@H]1(CO)OC([C@H](N)[C@@H](O)[C@@H]1O)O.Cl \|&1:0,5,7,9,r\|
LogP	-2.375 (est)
CAS DataBase Reference	66-84-2(CAS DataBase Reference)
EPA Substance Registry System	D-Glucose, 2-amino-2-deoxy-, hydrochloride (66-84-2)

Safety Information

CAS:	4337-75-1
MF:	C15H32NNaO4S
MW:	345.47
EINECS:	224-388-8
Product Categories:
Mol File:	4337-75-1.mol

sodium 2-[methyl(1-oxododecyl)amino]ethanesulphonate Chemical Properties

Boiling point	363.5℃[at 101 325 Pa]
density	1.193[at 20℃]
vapor pressure	3.6Pa at 20℃
solubility	10mg/L in organic solvents at 20 ℃
pka	1.42[at 20 ℃]
form	Solid
color	White to Off-White
Water Solubility	180mg/L at 20℃
Stability:	Hygroscopic
LogP	-1.25 at 20℃
EPA Substance Registry System	Sodium N-lauroyl-N-methyltaurate (4337-75-1)

Product Pictures

Shop China Most Professional Factory Supply High Qulity Huperzine A CAS 102518-79-6-Detailed Image 2

About Our Group

Since 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture high quality raw materials and refined ingredients which is widely used at different industries areas like Pharm & chemicals industry, functional active ingredients industry, nutritional Ingredients industry, health care products industry, cosmetics industry, pharmaceutical and refined food, feed, oil industry, natural plant ingredients industries, agriculture industry etcs to provide top quality of GMP standards products.

All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, agriculture raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China.

Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research. Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates.

With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products. Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people.

We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.

We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

Our Factories Production Lines

Shop China Largest factory Manufacturer Supply High Qulity Sodium Cocoyl Glutamate CAS 68187-32-6-Detailed Image 4

Our Factories R&D ability

Shop China Largest factory Manufacturer Supply High Qulity Sodium Cocoyl Glutamate CAS 68187-32-6-Detailed Image 7

Our Factories warehouse 52000㎡

Shop China Largest factory Manufacturer Supply High Qulity Sodium Cocoyl Glutamate CAS 68187-32-6-Detailed Image 10

Sales Team

Shop China Largest factory Manufacturer Supply High Qulity Glabridin CAS 59870-68-7-Detailed Image 11

ECHEMI Editorial Reference

12-o-tetradecanoylphorbol-13-acetate appears as white crystals. (NTP, 1992)
12-o-tetradecanoylphorbol-13-acetate appears as white crystals. (NTP, 1992)|Phorbol 13-acetate 12-myristate is a phorbol ester that is phorbol in which the hydroxy groups at the cyclopropane ring juction (position 13) and the adjacent carbon (position 12) have been converted into the corresponding acetate and myristate esters. It is a major active constituent of the seed oil of Croton tiglium. It has been used as a tumour promoting agent for skin carcinogenesis in rodents and is associated with increased cell proliferation of malignant cells. However its function is controversial since a decrease in cell proliferation has also been observed in several cancer cell types. It has a role as a protein kinase C agonist, an antineoplastic agent, a reactive oxygen species generator, a plant metabolite, a mitogen, a carcinogenic agent and an apoptosis inducer. It is an acetate ester, a tetradecanoate ester, a diester, a tertiary alpha-hydroxy ketone and a phorbol ester.|Tetradecanoylphorbol Acetate is a phorbol ester with potential antineoplastic effects. Tetradecanoylphorbol acetate (TPA) induces maturation and differentiation of hematopoietic cell lines, including leukemic cells. This agent may induce gene expression and protein kinase C (PKC) activity. In addition to potential antineoplastic effects, TPA may exhibit tumor promoting activity. (NCI04)|A phorbol ester found in CROTON OIL with very effective tumor promoting activity. It stimulates the synthesis of both DNA and RNA.

Certificates

Basic Info

Product Name:

Phorbol 12-myristate 13-acetate

Other Name:

Tetradecanoic acid,(1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-(acetyloxy)-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1H-cyclopropa[3,4]benz[1,2-e]azulen-9-yl ester;Myristic acid,9-ester with 1,1aα,1bβ,4,4a,7aα,7b,8,9,9a-decahydro-4aβ,7bα,9β,9aα-tetrahydroxy-3-(hydroxymethyl)-1,1,6,8α-tetramethyl-5H-cyclopropa[3,4]benz[1,2-e]azulen-5-one 9a-acetate,(+)-;Tetradecanoic acid,9a-(acetyloxy)-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1H-cyclopropa[3,4]benz[1,2-e]azulen-9-yl ester,[1aR-(1aα,1bβ,4aβ,7aα,7bα,8α,9β,9aα)]-;1H-Cyclopropa[3,4]benz[1,2-e]azulene,tetradecanoic acid deriv.;13-O-Acetylphorbol 12-myristate;Phorbol myristate acetate;12-O-Tetradecanoylphorbol 13-acetate;Factor A1 (croton oil);12-Tetradecanoylphorbol 13-acetate;Tetradecanoylphorbol acetate;Phorbol 12-tetradecanoate 13-acetate;Phorbol 12-myristate 13-acetate;TPA;Factor A1;PMA;4β-Phorbol 12-myristate 13-acetate;PMA (tumor promoter);β-Phorbol 12-myristate 13-acetate;12-Tetradecanoylphorbol 13-monoacetate;TPA (phorbol derivative);NSC 262244;PD 616;11016-13-0;11019-85-5;20839-11-6;26894-58-6;27534-73-2;51898-14-7

CAS No.:

16561-29-8

Molecular Formula:

C36H56O8

InChIKeys:

InChIKey=PHEDXBVPIONUQT-RGYGYFBISA-N

Molecular Weight:

616.82500

Exact Mass:

616.83

EC Number:

605-413-5

UNII:

NI40JAQ945

NSC Number:

626496|262644

UN Number:

2811

DSSTox ID:

DTXSID5023798

NCI Thesaurus Code:

C866

Color/Form:

Oil|White crystals|Colorless powder|Amorphous film, solid

Categories:

Plant Extracts

Characteristics

PSA:

130.36000

XLogP3:

5.75290

Appearance:

White to off-white solid.

Density:

1.17 g/cm3

Melting Point:

162 °F (NTP, 1992)|50-70 °C (melting pt-freezing pt)

Boiling Point:

698.1ºC at 760 mmHg

Flash Point:

208.1ºC

Refractive Index:

1.553

Water Solubility:

Practically insoluble (NTP, 1992)|Insoluble in water|Soluble in DMSO (25 mg/mL), 100% ethanol (25 mg/mL), acetone, ether, DMF, methanol, and chloroform; insoluble in aqueous buffers

Storage Conditions:

-20ºC

Vapor Pressure:

1.55E-22mmHg at 25°C

Henrys Law Constant:

Henry's Law constant = 4.7X10-12 atm-cu m/mol at 25 °C (est)

Dissociation Constants:

pKa 12.6 at 25 °C (est)

Experimental Properties:

Sensitive to acids and alkalis|Protect from light|Hydroxyl radical reaction rate constant = 2.1X10-10 cu cm/molecule-sec at 25 °C (est)

Air and Water Reactions:

Practically water insoluble.

Reactive Group:

Alcohols and Polyols

Reactivity Profile:

12-O-TETRADECANOYLPHORBOL-13-ACETATE is sensitive to acids and alkalis. (NTP, 1992).

See More Phorbol 12-myristate 13-acetate Properties 

Seller Information

Business Type:
Manufactory

Main Products:
Biochemicals Ingredients,Vitamin Amino Acid Ingredients,Cosmestic Ingredients,Pharma Chemicals,Organic Fine Chemicals,Food Nutrient Ingredients

Location:
National Aerospace Economic & Technical Development Zone,Chang'an,Xi'an,China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
5

Total Annual Revenue:
$10 million-$25 million

Total Employees:
Above 1000

Year of Establishment:
2014

Certifications:
Level A of Tax Credit Registration Assessment by Government,Good Product Quality Management Certificate of Shanxi Province,China,Company Trade Union Qualification Certificate,Excellent Group Enterprise of Quality and credit in Shaanxi ProvinceChina,AAA TOP Credit Excellent Group Enterprise of Shanxi Province,China,FDA
24 Hours Team Service
Email
info@leader-biogroup.com
Hot Line
+86-029-68895030
+86-029-68569961
+86-029-68569962
Fax
+86-029-68895030

Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories Base with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world.
- Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.
  
  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.
  
  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.
  
  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.
- Process Capability : It has more than 100 sets of multi-functional reaction reactors, such as 100l~6300l enamel, stainless steel, Hastelloy, etc. It can realize Grignard, coupling, bromination, Wittig reaction and other conventional reactions. There are microchannel reactor workshops, which can realize continuous production, energy conservation and emission reduction. It can realize high pressure, high vacuum rectification, ultra-low temperature (-80 ℃ ~-100 ℃), ultra-high temperature (300 ℃ ~400 ℃) and other special reactions. It can realize the customization and processing of customers' products.
Factory Overview

   Factory Production Lines

Our Professional Lab

Factory Warehouse

Factory Logistics Departments
GROUP HONOR
Honor Name: Level A of Tax Credit Registration Assessment
Issued By:National Administration of Taxation & Shaanxi Tax Bureau
Authorised Date:2018-09-16
Description: National Administration of Taxation & Shaanxi Tax Bureau

Honor Name: AAA TOP Credit Excellent Group Enterprise of Shanxi Province,China
Issued By:China Association of Shaanxi product Quality management Center
Authorised Date:2018-12-31
Description:AAA TOP Credit Excellent Group Enterprise of Shanxi Province,China

Honor Name:Excellent Group Enterprise of Quality and credit in Shaanxi ProvinceChina
Issued By: China Association of Shaanxi product Quality management Center
Authorised Date:2018-12-31
Description: Excellent Group Enterprise of Quality and Integrity in Shaanxi Province,China

Honor Name: Products Patent Certificates
Country Product Purchase Quantity Date Posted

Post an enquiry for this product

More Choices Find All Products for Sale 

Product Name	Grade / Content	Price	Supplier Name	Details
PHORBOL 12-MYRISTATE 13-ACETATE	/99.00		HANGZHOU LEAP CHEM CO., LTD.	Inquiry

Email	info@leader-biogroup.com
Hot Line	+86-029-68895030
	+86-029-68569961
	+86-029-68569962
Fax	+86-029-68895030

China Most Professional Factory Supply High Qulity Phorbol-12-Myristate-13-Acetate CAS 16561-29-8

Product Description

Seller Information

Factory Logistics Departments

GROUP HONOR

More Choices Find All Products for Sale 

Related Searches