 Home > Active Pharmaceutical Ingredients > Inhibitor Drugs > N-[5-(Aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamide for Sale > PRITELIVIR

PRITELIVIR

7 Inquiries

Unit Price: Get Latest Price 

CAS No.:

348086-71-5

Grade:

Pharmaceutical Grade

Content:

99%

Port:

ShangHai

Packaging:

bags

Price valid (until):

2024-02-08

Contact Supplier

 Chat Now

HANGZHOU TIANYE CHEMICALS CO., LTD

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Di-n-butyl naphthalene-2,6-dicarboxylate

 Visit Store

Product Description
Seller Information
Inquiry History

Description

Product Detail

bay 57-1293 is a potent and safe inhibitor of hsv helicase-primase with ic50 value of 12nm [1].bay 57-1293 displays anti-herpes activity through inhibiting the helicase-primase and affecting the viral dna synthesis. in the in vitro viral replication assay, bay 57-1293 shows inhibition against hsv-1 f, hsv-2 g and acyclovir-resistant hsv-1 f mutant with ic50 value of 20nm. in the plaque reduction assay and the conventional cytopathogenicity assay, bay 57-1293 shows ic50 values of 0.01-0.02μm and 0.01-0.03μm, respectively. besides that, bay 57-1293 is active at an ic50 value of 10nm–30nm against all clinical isolates of hsv-1 and hsv-2. furthermore, bay 57-1293 is active in vivo. the oral administration of bay 57-1293 shows 10-fold more potent than valacyclovir in a murine model of disseminated herpes infection. in a rat lethal challenge model, bay 57-1293 exerts profound antiviral activity without toxic effects. [1, 2]

Items	Specifications
Boiling point	639.4±65.0 °C(Predicted)
density	1.396±0.06 g/cm3(Predicted)
storage temp.	2-8°C(protect from light)
solubility insoluble in H2O; insoluble in EtOH;	≥13.9 mg/mL in DMSO form solid
form	solid
pka	9.31±0.60(Predicted)

Basic Info

Product Name:

N-[5-(Aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamide

Other Name:

Benzeneacetamide,N-[5-(aminosulfonyl)-4-methyl-2-thiazolyl]-N-methyl-4-(2-pyridinyl)-;N-[5-(Aminosulfonyl)-4-methyl-2-thiazolyl]-N-methyl-4-(2-pyridinyl)benzeneacetamide;BAY 57-1293;N-[5-(Aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamide;Pritelivir

CAS No.:

348086-71-5

Molecular Formula:

C18H18N4O3S2

InChIKeys:

InChIKey=IVZKZONQVYTCKC-UHFFFAOYSA-N

Molecular Weight:

402.49052

Exact Mass:

402.49

UNII:

07HQ1TJ4JE

DSSTox ID:

DTXSID70188344

NCI Thesaurus Code:

C136516

Categories:

Inhibitor Drugs

Characteristics

PSA:

143

XLogP3:

2.1

Density:

1.4±0.1 g/cm3

Boiling Point:

639.4±65.0°C at 760 mmHg

Flash Point:

340.5±34.3 °C

Refractive Index:

1.648

See More N-[5-(Aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamide Properties 

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More N-[5-(Aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamide Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Di-n-butyl naphthalene-2,6-dicarboxylate

Location:
1208# HuaCe Building-B,Wuchanggang Road,XIHU District,Hangzhou City,Zhejiang Province ,China

Payment Terms:
TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
15

Total Annual Revenue:
$5 million-$10 million

Total Employees:
5-10

Year of Establishment:
2023

Inquiry History

7 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	CAS 348086-71-5	5 G	Nov 6, 2023
United States	BAY-57-1293	1 G	Nov 6, 2023
Spain	Pritelivir	100 G	Feb 20, 2024
Spain	Pritelivir	200 G	Jun 26, 2026
Thailand	Pritelivir	1 KG	Aug 6, 2024
United States	Pritelivir	1 MT	Feb 3, 2024
United Kingdom	Pritevilla	100 KG	Jan 6, 2024

Post an enquiry for this product

More Choices Find All Products for Sale 

Product Name	Grade / Content	Price	Supplier Name	Details
Pritelivir348086-71-5	/	$1/G FOB	Conier Chem&Pharma Limited	Inquiry
BAY-57-1293 AIC316 Pritelivir New Product Senwayer	Pharmaceutical Grade/98		Dingwang Technology (Wuhan) Co., Ltd.	Inquiry
BAY-57-1293 PRITELIVIR	PRITELIVIR/		SHANDONG LOOK CHEMICAL CO.,LTD	Inquiry
BAY-57-1293	/99.00		HANGZHOU LEAP CHEM CO., LTD.	Inquiry
Wuhan PNQ supply pritelivir	Chemical Grade/99		Wuhan Pnq Int Trade Co., Ltd	Inquiry