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Tirzepatide 99% white powder, glp-1, GIP, Bulk powder for Injection

TDS 503 Inquiries

Unit Price: Get Latest Price 

CAS No.:

910463-68-2

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Xiamen, Shanghai

Brand:

Top Health

Packaging:

10g/bottle, 100g/bottle, 10~1000g/bottle

Price valid (until):

2025-02-01

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Xiamen Top Health Biochem Tech. Co.,Ltd

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Peptide,GLP-1,Semaglutide,Semaglutide Powder,910463-68-2,Semaglutide Pen Injector

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Product Description
Seller Information
Inquiry History

Description

Tirzepatide Chemical Properties

storage temp.	Store at -20°C
solubility	Soluble in DMSO

Tirzepatide Usage And Synthesis

Description	Tirzepatide (LY3298176) was developed as a dual agonist to both GLP-1 and gastric inhibitory polypeptide (GIP) receptors (Frias et al., 2018). Similar to GLP-1, GIP is an incretin hormone that functions to induce insulin secretion.
Uses	Tirzepatide is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems.
Mechanism of action	It works to stimulate first- and second-phase insulin secretion, and reduces glucagon levels, both in a glucose-dependent manner. Tirzepatide was also shown to delay gastric emptying, lower fasting and postprandial glucose concentration, decrease food intake, 4 and reduce body weight in patients with type 2 diabetes.
Pharmacology	Tirzepatide is a once-weekly GIP (glucose-dependent insulinotropic polypeptide) receptor and GLP-1 (glucagon-like peptide-1) receptor agonist that integrates the actions of both incretins into a single novel molecule. GIP is a hormone that may complement the effects of GLP-1 receptor agonists. In preclinical models, GIP has been shown to decrease food intake and increase energy expenditure therefore resulting in weight reductions, and when combined with GLP-1 receptor agonism, may result in greater effects on markers of metabolic dysregulation such as body weight, glucose and lipids. Tirzepatide is in phase 3 development for adults with obesity or overweight with weight-related comorbidity and is currently under regulatory review as a treatment for adults with type 2 diabetes. It is also being studied as a potential treatment for non-alcoholic steatohepatitis (NASH) and heart failure with preserved ejection fraction (HFpEF). Studies of tirzepatide in obstructive sleep apnea (OSA) and in morbidity/mortality in obesity are planned as well.
Mode of action	Tirzepatide has a greater affinity to GIP receptors than to GLP-1 receptors, and this dual agonist behaviour has been shown to produce greater reductions of hyperglycemia compared to a selective GLP-1 receptor agonist. Signaling studies have shown that this is due to tirzepatide mimicking the actions of natural GIP at the GIP receptor. However, at the GLP-1 receptor, tirzepatide shows bias towards cAMP (a messenger associated with regulation of glycogen, sugar and lipid metabolism) generation, rather than β-arrestin recruitment. This combination of preference towards GIP receptor and distinct signaling properties at GLP-1 suggest this biased agonism increases insulin secretion. Tirzepatide has also been shown to increase levels of adiponectin, an adipokine involved in the regulation of both glucose and lipid metabolism, with a maximum increase of 26% from baseline after 26 weeks, at the 10 mg dosage.
Clinical claims and research	Tirzepatide , a novel, once-weekly injectable dual glucose-dependent insulinotropic polypeptide (GIP) receptor and GLP-1 RA combination drug, has been developed to treat patients with T2DM.

Items

Specifications

Product name

Tirzepatide

Appearance

White to off-whtite powerder or loose lumps.

Packing

1g/Bottle or Customized

Tirzepatide Purity>99% USD295/g~USD335/g, according to your order quantity.

Certificates

Basic Info

Product Name:

Semaglutide

Other Name:

semaglutide;Unknown (acetate);NN9535;Semaglutide [USAN:INN];Sermaglutide;NN 9535;NNC 0113-0217

CAS No.:

910463-68-2

Molecular Formula:

C187H291N45O59

InChIKeys:

DLSWIYLPEUIQAV-CCUURXOWSA-N

Molecular Weight:

4113.57754

Exact Mass:

4113.122087 g/mol

Categories:

Polypeptide

Characteristics

PSA:

1650 Å²

XLogP3:

5.44520

See More Semaglutide Properties 

Hazard Identification

Classification of the substance or mixture

Reproductive toxicity, Category 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H361 Suspected of damaging fertility or the unborn child
Prevention	P203 Obtain, read and follow all safety instructions before use. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P318 IF exposed or concerned, get medical advice.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Semaglutide Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Peptide,GLP-1,Semaglutide,Semaglutide Powder,910463-68-2,Semaglutide Pen Injector

Location:
5 Floor, MouFu Building, HuLi Zone, Xiamen, Fujian, China.

Payment Terms:
TT against copy of documents,L/C,100% TT in advance

Average lead Time:
7

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2014

Xiamen Top Health Biochem Tech. Co.,Ltd. was established in 2008 in Xiamen, China, and now has been a leading group specialized in custom developing, custom manufacturing and trading of Medicine， our products including but not limited to:
Pharmaceutical raw mateiral)APIs
pharmaceutical intermediates
cosmetic raw materials
herbal extracts
health&food supplements
finish dosage form(FDF)
Animal Drug
Pesticide
Semaglutide and Tirzepatide
We have 20 years experience of exporting to North America, South America, Euro, Middle East, Japan, Korea, Vietnam and other Asia countries, etc.
We have cooperated with local Medicine Inspection Center as our QC center.
We havecustomer manufacture sites managed under GMP guidline in Zhejiang and Jiangsu Province, China.
We accepted audits both from end-users and from authorities like PMDA.
We have good relationship with many pharmaceutical research Institute and Universities in China.

Inquiry History

503 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	Weight Loss Semaglutide intermediate 99% White powder COA High Quality peptide GLP-1 910463-68-2	5 MG	Apr 11, 2024
United States	Gene-Biocon Semaglutide 910463-68-2 GLP-1analogs diabetes weight loss 96% White or off-white powder	2	Dec 5, 2023
United States	Semaglutide 910463-68-2	1 G	Sep 21, 2023
China	Semaglutide CAS 910463-68-2	1 KG	Apr 16, 2026
United Kingdom	Semaglutide 910463-68-2 Muhuang	100 G	Aug 18, 2023
United States	Sermaglutide 99% 910463-68-2	2 KG	Oct 21, 2023
United Kingdom	TGYFactory Supply Semaglutide Peptide 99% CAS 910463-68-2	50 MT	Nov 13, 2023
United States	Semaglutide Powder CAS 910463-68-2 Blood Sugar Regulation	5 G	Aug 3, 2023
Sri Lanka	Bulk Supply 98% up Sermaglutide powder CAS 910463-68-2	300 G	Nov 18, 2023
United States	Semaglutide Ozempic Sermaglutide 99.9% white powder 910463-68-2 Teruiop	500 G	Oct 9, 2023
United States	Raw mateiral Semaglutide CAS 910463-68-2 99% White powder	1000 G	Sep 23, 2023
United States	10MG vial pack Semaglutide 99% 910463-68-2 GLP-1 Peptide	10 MT	Oct 18, 2023
Switzerland	Semaglutide Ozempic Sermaglutide 99.9% white powder 910463-68-2 Teruiop	5000 MT	Sep 13, 2023
United States	High Purity Peptide Semaglutide 910463-68-2 With Safe Shipping	1 G	Sep 7, 2023
United States	High Purity IGF-1 LR3 Peptide CAS 910463-68-2 IGF1 LR3	60 MG	Aug 4, 2025
South Korea	API Pharmaceutical Chemical Grade Raw Materials CAS 910463-68-2 Semaglutide	3 G	Jul 27, 2023
China	Semaglutide Tirzepatide for Weight Loss CAS: 910463-68-2 Retatrutide Cagrilintide	1 MT	Jul 5, 2025
United States	API Pharmaceutical Chemical Grade Raw Materials CAS 910463-68-2 Semaglutide	1 G	Jul 26, 2023
United States	High Purity IGF-1 LR3 Peptide CAS 910463-68-2 IGF1 LR3	10 MT	Sep 19, 2025
United States	High Purity IGF-1 LR3 Peptide CAS 910463-68-2 IGF1 LR3	2	Nov 13, 2024

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