Efpeglenatide zjl
ISO
1296200-77-5
Chemical Grade
98%
Dideu
1g/bag
2026-12-17
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst
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Product Description
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Seller Information
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DescriptionECHEMI Editorial Reference
Efpeglenatide (CAS No. 1296200-77-5) is a long-acting GLP-1 receptor agonist and peptide-based pharmaceutical ingredient. As a pharmaceutical raw material, Efpeglenatide is characterized by its modified peptide structure and long-acting properties. It is suitable for API research, analytical testing, pharmaceutical development, and related manufacturing processes.
CertificatesBasic Info-
Product Name:
Efpeglenatide
CAS No.:1296200-77-5
Categories:
Research-
Class:
GLP-1 receptor agonist (exendin-based, long-acting via Fc fusion + pegylation)
Status:Investigational — Phase 3 completed, development discontinued (Sanofi returned rights 2021)
Mechanism:A long-acting GLP-1 receptor agonist based on a modified exendin-4 peptide conjugated to a small Fc fragment with polyethylene glycol (PEG) modification. The combination of Fc fusion and pegylation extends the half-life to ~5 days, allowing once-weekly dosing. Activates GLP-1R to improve insulin sensitivity, reduce blood glucose, and decrease body weight.
EC50 (GLP1R Ki):~0.1 nM (approximate, exendin-based)
Source:MCE: Efpeglenatide (CAS 1296200-77-5); AbMole product data sheet.
Clinical Development:
References-
PubChem:Disclaimer:
Efpeglenatide is NOT FDA-approved. Phase 3 development was completed but the program was discontinued after Sanofi returned rights to Hanmi in 2021. This listing is for industrial and laboratory research use only. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst
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Location:
https://www.dideu.com/en/
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
7
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Total Annual Revenue:
Above $100 million
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Total Employees:
Above 1000
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Year of Establishment:
2016
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Certifications:
ISO Certificate,REACH
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