HPR-10 / HYDROXYPINACOLONE RETINOATE Skin Anti-Aging And Anti Wrinkle Ingredient

CAS No.: 129499-78-1

COSING REF No: 83238

Chem/IUPAC Name: 4-[(1E,3E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)-2,4,6,8-nonatetraen-1-yl]-3,5,5-trimethylcyclohex-3-en-1-one

Description:

Hydroxypinacolone retinoate (HPR) stands out as a newer and more stable member within the expanding retinoid family, a collection of powerful derivatives of vitamin A that deliver significant benefits to the skin.

While the name "hydroxypinacolone retinoate" might sound unfamiliar, you may already be familiar with its trade name, Granactive Retinoid. This particular type combines 10% HPR with 90% dimethyl isosorbide, serving as a solvent.

HPR is a versatile ingredient that interacts with the skin by binding to its retinoic acid receptors within the surface layers. Despite directly engaging with these receptors, HPR has demonstrated a gentler approach compared to retinoic acid (tretinoin) when applied topically. This gentleness makes it a viable alternative for individuals with more reactive and sensitive skin types.

Beyond its mild nature, research has shown that this retinoic acid ester offers both anti-aging and blemish-reducing advantages. Studies indicate that HPR, in combination with retinol glycospheres and papain glycospheres, effectively reduces the occurrence of mild breakouts and associated redness with minimal disruption to the skin barrier.

For those addressing fine lines, wrinkles, and uneven skin tone, HPR proves to be a valuable skincare ingredient. Research has demonstrated its ability to diminish the appearance of fine lines and wrinkles, along with improving uneven skin tone.

HPR can exert positive effects on the skin even at low percentages, starting from 0.02%. However, its efficacy significantly diminishes when improperly packaged, particularly when stored in jars exposed to light and air. Similar to other vitamin A derivatives and antioxidants, HPR requires air-tight, opaque packaging to maintain its potency.