Pharmaceutical Intermediate Memantine CAS 19982-08-2 with Best Price 99% white powder
7 Inquiries
19982-08-2
Pharmaceutical Grade
99%
深圳
1kg/bag;25kg/Cardboard Drum
2024-04-28
Estradiol,Progesterone,GS441524,4-Butylresorcinol,DeoxyArbutin,Coenzyme Q10
-
Product Description
-
Seller Information
-
Inquiry History
-
DescriptionECHEMI Editorial ReferenceChEBI: A primary aliphatic amine that is the 3,5-dimethyl derivative of 1-aminoadamantane. A low to moderate affinity uncompetitive (open-channel); NMDA receptor antagonist which binds preferentially to the NMDA receptor-operated cation channels.
Solid
Memantine is a primary aliphatic amine that is the 3,5-dimethyl derivative of 1-aminoadamantane. A low to moderate affinity uncompetitive (open-channel); NMDA receptor antagonist which binds preferentially to the NMDA receptor-operated cation channels. It has a role as a dopaminergic agent, an antiparkinson drug, a NMDA receptor antagonist, a neuroprotective agent and an antidepressant. It is a member of adamantanes and a primary aliphatic amine. It is a conjugate base of a memantinium(1+). It derives from a hydride of an adamantane.|Initially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD). It is different from many other Alzheimer's Disease medications, as it works by a different mechanism than the cholinesterase enzyme inhibitors normally employed in the management of Alzheimer's disease. Memantine blocks the effects of glutamate, a neurotransmitter in the brain that leads to neuronal excitability and excessive stimulation in Alzheimer's Disease. In 2010, it was estimated that 36 million people worldwide live with Alzheimer's Disease. In 2013, this number increased to 44 million. Almost doubling every 20 years, the prevalence of Alzheimer's Disease is predicted to reach 66 million by 2030 and to 115 million by 2050. In December 2013, the G8 dementia summit concluded that dementia should be considered a global priority with the objective of developing a cure or a disease-modifying therapy by the year 2025.|Memantine is a N-methyl-D-aspartate Receptor Antagonist. The mechanism of action of memantine is as a NMDA Receptor Antagonist.|Memantine is an oral N-methyl-D-aspartate glutamate receptor antagonist used in the therapy of Alzheimer disease and dementia. Memantine is associated with a minimal rate of serum enzyme elevations during therapy and has only rarely been implicated as a cause of clinically apparent acute liver injury.|AMANTADINE derivative that has some dopaminergic effects. It has been proposed as an antiparkinson agent.Research & Reference NotePharmaceutical Intermediate Memantine CAS 19982-08-2 with Best Price 99% white powder is listed on ECHEMI for industrial / laboratory sourcing. This listing is for industrial and laboratory research use. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.
Authoritative sourcesDisclaimer: This listing is for industrial and laboratory research use. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.
Reviewed by ECHEMI Scientific Review - Platform editorial review for research chemicals
Basic Info-
Product Name:
Memantine
Other Name:Tricyclo[3.3.1.13,7]decan-1-amine,3,5-dimethyl-;1-Adamantanamine,3,5-dimethyl-;3,5-Dimethyltricyclo[3.3.1.13,7]decan-1-amine;1,3-Dimethyl-5-aminoadamantane;3,5-Dimethyl-1-adamantylamine;D 145;1-Amino-3,5-dimethyladamantane;1,3-Dimethyl-5-adamantanamine;Memantine;D 145 (sympathomimetic);DMAA;DRG 0267;Memantina;Alzantin;3,5-Dimethyl-1-adamantanamine;3,5-Dimethyl-adamantan-1-ylamine;Nemdatine;51052-62-1
CAS No.:19982-08-2
Molecular Formula:C12H21N
InChIKeys:InChIKey=BUGYDGFZZOZRHP-UHFFFAOYSA-N
Molecular Weight:179.3
Exact Mass:179.30
EC Number:1308068-626-2
UNII:W8O17SJF3T
DSSTox ID:DTXSID5045174
Color/Form:Oil
ATC Code:N06DX01|N - Nervous system
HScode:2921300090
Categories:
Characteristics-
PSA:
26
XLogP3:3.5
Appearance:Solid
Density:1.046
Melting Point:258 °C
Boiling Point:239.8±8.0 °C(Predicted)
Flash Point:92.3±9.7 °C
Refractive Index:nD25 1.4941
Water Solubility:4.55e-02 g/L
Storage Conditions:Store at RT
Vapor Pressure:1.9X10-4 mm Hg at 25 deg C (est)
PKA:10.27None
Henrys Law Constant:Henry's Law constant = 1.47X10-5 atm-cu m/mole at 25 °C (est)
Dissociation Constants:10.27|pKa = 10.7 (est)
Experimental Properties:Hydroxyl radical reaction rate constant = 3.34X10-11 cu cm/molec-sec at 25 °C (est)
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
-
-
Seller Information
-
Business Type:
Trader
-
Main Products:
Estradiol,Progesterone,GS441524,4-Butylresorcinol,DeoxyArbutin,Coenzyme Q10
-
Location:
XINYUAN DADUHUI PHASE 1, NO.258 TAOYUAN NORTH ROAD, LIANHU DISTRICT, XI 'AN , SHAANXI CHINA
-
Payment Terms:
TT against copy of documents,100% TT in advance
-
Average lead Time:
30
-
Total Annual Revenue:
$2.5 million-$5 million
-
Total Employees:
11-50
-
Year of Establishment:
2023
-
-
Inquiry History7 Inquiries
Country Product Purchase Quantity Date Posted 
Canada
Manufacturer Supply Pharmaceutical Intermediate Memantine CAS 19982-08-2 with Best Price 99% white powder Lingding-81 Lingding
10 G Sep 26, 2023 
Lithuania
Memantine 99% white powder
1 KG May 19, 2026
Lithuania
Memantine
10 G Feb 17, 2025 
Australia
memantine base form
50 G Jan 6, 2025 
Colombia
Memantine
10 G Oct 28, 2025 
Netherlands
memantine
10000 MG Jun 11, 2024 
United Kingdom
Pharmaceutical Intermediate Memantine CAS19982-08-2 99% Fine powders HHD Wuhan hhd
1 G Mar 2, 2024 Post an enquiry for this product
- Hot Searches
- etoricoxib
- carbon black pricing
- tirzepatide research peptide for sale
- na 931 peptide buy
- verochem
- calcium ammonium nitrate for sale
- where to buy methyl anthranilate
- buy primobolan online
- ethyl acetate cost
- ethyl acetate price
- nyquil vs dayquil ingredients
- buy testosterone cypionate powder