110417-88-4 | ChemExpress
110417-88-4
shanghai
10 kg
2024-04-01
CRO
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceChEBI: Dolastatin 10 is a tetrapeptide that is isolated from the sea hare Dolabella auricularia. It is a potent anticancer agent which inhibits tubulin polymerization. It has a role as an animal metabolite, a marine metabolite, an antineoplastic agent, an apoptosis inducer and a microtubule-destabilising agent. It is a member of 1,3-thiazoles and a tetrapeptide. It is functionally related to a L-valine.Basic Info
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Product Name:
dolastatin 10
Other Name:(2S)-2-[[(2S)-2-(dimethylamino)-3-methylbutanoyl]amino]-N-[(3R,4S,5S)-3-methoxy-1-[(2S)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-[[(1S)-2-phenyl-1-(1,3-thiazol-2-yl)ethyl]amino]propyl]pyrrolidin-1-yl]-5-methyl-1-oxoheptan-4-yl]-N,3-dimethylbutanamide;Dolastain10;Dolastatin 10 (NSC-376128);L-Valinamide, N,N-dimethyl-L-valyl-N-[2-methoxy-4-[2-[1- methoxy-2-methyl-3-oxo-3-[[2-phenyl-1-(2-thiazolyl)ethyl] amino]propyl]-1-pyrrolidinyl]-1-(1-methylpropyl)-4-oxobutyl]-N-methyl-;dolastatin 10;B720389K560;From dolabella auricularia (sea hare);L-Valinamide, N,N-dimethyl-L-valyl-N-[2-methoxy-4-[2-[1- methoxy-2-methyl-3-oxo-3-[[2-phenyl-1-(2-thiazolyl)ethyl] amino]propyl]-1-pyrrolidinyl]-1-(1-methylpropyl)-4-oxobutyl]-N-methyl-, [2S-[1[1R*(R*),2S*],2R*[1S*,2S*,3(R*)]]]-
CAS No.:110417-88-4
Molecular Formula:C42H68N6O6S
InChIKeys:InChIKey=OFDNQWIFNXBECV-VFSYNPLYSA-N
Molecular Weight:785.09
Exact Mass:785.09
Color/Form:White to off-white
Categories:
Characteristics-
Density:
1.116±0.06 g/cm3(Predicted)
Melting Point:107～112
Boiling Point:903.6±65.0 °C(Predicted)
PKA:13.81±0.46(Predicted)
Critical Temperature & Pressure:Store at -20°C,unstable in solution, ready to use.
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Seller Information
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Business Type:
Manufactory
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Main Products:
CRO
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Location:
1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USA
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Payment Terms:
TT against copy of documents
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Average lead Time:
3 days
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
Above 1000
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Year of Establishment:
2006
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