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21343-40-8 | ChemExpress

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CAS No.:

21343-40-8

Port:

shanghai

Packaging:

10 kg

Price valid (until):

2024-04-01

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ChemExpress

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

CRO

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Product Description
Seller Information

Description

25-OH Vitamin D2

Hyperparathyroidism
We can provide high-quality 25-OH Vitamin D2 and its derived impurities.

Brand：ChemExpress
CAS：21343-40-8
Catalog_No：HY-32349
Molecular Formular:C28H44O2
Molecular Weight:412.65

Contact:
TEL：+1-970-439-2030 (USA)、+86 (21) 5895-0125 (Global)
Email：info@chemexpress.com

Brand Introduction:
ChemExpress focuses on providing small molecule and new modalities CDMO services for both pharmaceutical and biotech clients. Our comprehensive CRO & CDMO platform is engaged in the research and development, manufacturing and supply of regulatory starting materials, novel building blocks, intermediates, reference compounds, APIs and drug products. We are a one-stop service platform to support our client’s projects from early drug discovery, process development to commercialization.

ChemExpress Services:

Drug Discovery: synthetic chemistry; medicine chemistry; FTE/FFS services.

Process Development: APIs and intermediates development; formulation development.

New Modalities Development: ADC; peptide; oligonucleotide and so on.

Manufactory: support production from milligrams to kilograms, both with GMP and non-GMP capabilities.

Analytical Development & Quality Control: R&D testing; stability study; genotoxic impurity research and so on.

Regulatory CMC Support

Eany development services in Synthetic Chemistny:Providing serices related to high qualty compound synthesis,chemical custom synthesis and analytical chemistry.

Pharmaceutical Chemistry eaniy development services: including high-throughput screening, drug synthesis, seding compounds, lead compounds, and IND fling support.

Process development: Covers AP! & intermediates process development, validation, transfer, and formulation development.

Commerial producion:it hasa research and development base forthe producion otapis intermediates and prenarations and provdes commeria prouction semices.

CMC services: Provide one-stop CMC services, from lND to NDA stage of pharmaceutical research and development and dedlaration services, accelerate IND declaration.

ADC drug and highly active drug development and production: Provides a one-stop CRO & CDMO service for the small molecule aspect of ADC drugs, as well as customized ADC conjugation services.

Oligonucleotide drug process development and production: Provide oligonucleotide customized products and services to meet different needs.

Analytical testing services and quality control: Provide integrated analytical testing services and drug quality research support

ChemExpress committed to being a steadfast companion for our clients, gaining profound insight into their needs. Our focus is on accelerating the empowerment of global partners across the full spectrum, from preclinical stages to commercial production. This commitment aims for more streamlined drug development, swifter market entry, and an earlier positive impact on human health.

Product details：https://www.chemexpress.com/product/HY-32349

ECHEMI Editorial Reference

Ercalcidiol is a metabolite of vitamin D2, is regarded as an indicator of vitamin D nutritional status.
9,10-Secoergosta-5,7,10(19),22-tetraene-3,25-diol. Biologically active metabolite of vitamin D2 which is more active in curing rickets than its parent. The compound is believed to attach to the same receptor as vitamin D2 and 25-hydroxyvitamin D3.
Off-White Solid
ChEBI: A hydroxycalciol that is vitamin D2 in which the hydrogen at position 25 has been replaced by a hydroxy group.
25-Hydroxyvitamin D2(ergocalciferol or 25-hydroxycalciferol) is a metabolite of vitamin D found in the liver. It is one of the most common forms of vitamin D circulating in the body and plays an important role in determining vitamin D deficiency.

Basic Info

Product Name:

25-HYDROXYVITAMIN D2

Other Name:

25-Hydroxyvitamin D2 solution;Ercalcidiol d6;25-Hydroxyvitamin D2, >=98%;25-HydroxyvitaMin D2 25-Hydroxyergocalciferol;4-methylene-3-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R,2E,4S)-5-hydroxy-1,4,5-trimethyl-2-hexenyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-cyclohexanol;25-HYDROXYVITAMIN D2 >= 98.0% (HPLC&;25-hydroxycalciferol;25-hydroxyvitamind

CAS No.:

21343-40-8

Molecular Formula:

C28H44O2

InChIKeys:

KJKIIUAXZGLUND-ICCVIKJNSA-N

Molecular Weight:

412.65

Exact Mass:

412.65

BRN:

4716773

EC Number:

606-742-7

DSSTox ID:

DTXSID00517562

Color/Form:

White to off-white

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

40.46000

XLogP3:

7.56

Density:

1.02±0.1 g/cm3(Predicted)

Melting Point:

45-51°C

Boiling Point:

542.3±38.0 °C(Predicted)

Flash Point:

14℃

Refractive Index:

1.543

Storage Conditions:

−20°C

Vapor Pressure:

5.06E-14mmHg at 25°C

PKA:

14.74±0.20(Predicted)

Critical Temperature & Pressure:

Keep in dark place,Sealed in dry,Store in freezer, under -20°C

See More 25-HYDROXYVITAMIN D2 Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 3, Oral

Acute toxicity - Category 3, Dermal

Acute toxicity - Category 2, Inhalation

Specific target organ toxicity â repeated exposure, Category 1

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H301+H311 Toxic if swallowed or in contact with skin H330 Fatal if inhaled H372 Causes damage to organs through prolonged or repeated exposure
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P260 Do not breathe dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area. P284 [In case of inadequate ventilation] wear respiratory protection.
Response	P301+P316 IF SWALLOWED: Get emergency medical help immediately. P321 Specific treatment (see ... on this label). P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P316 Get emergency medical help immediately. P361+P364 Take off immediately all contaminated clothing and wash it before reuse. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P320 Specific treatment is urgent (see ... on this label). P319 Get medical help if you feel unwell.
Storage	P405 Store locked up. P403+P233 Store in a well-ventilated place. Keep container tightly closed.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More 25-HYDROXYVITAMIN D2 Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
CRO

Location:
1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USA

Payment Terms:
TT against copy of documents

Average lead Time:
3

Total Annual Revenue:
$2.5 million-$5 million

Total Employees:
Above 1000

Year of Establishment:
2006

Company Profile
Founded in 2006, ChemExpress focuses on providing small molecule and new modalities CDMO services for both pharmaceutical and biotech clients. Our comprehensive CRO & CDMO platform is engaged in the research and development, manufacturing and supply of regulatory starting materials, novel building blocks, intermediates, reference compounds, APIs and drug products. We are a one-stop service platform to support our client’s projects from early drug discovery, process development to commercialization.

Over the past 17 years, we have established a state-of-the-art QC/QA system aligning with ICH guidelines for pharmaceutical manufacturing. We provide our clients with high-quality products and CMC services across the entire life-cycle of drug development.
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