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High purity Niclosamide 98% with best price 50-65-7 and Niclosamide raw material

3 Inquiries

Unit Price:

$8.8-10/MT FOB

Get Latest Price 

CAS No.:

50-65-7

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shenzhen

Packaging:

1kg/bag;25kg/Cardboard Drum

Sample Available:

Yes

Price valid (until):

2321-01-08

Contact Supplier

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Xi'an Honest BioEngr Co.,Ltd.

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents,100% TT in advance

Average Lead Time:

30 days

Qualification:

Main Products:

Estradiol,Progesterone,GS441524,4-Butylresorcinol,DeoxyArbutin,Coenzyme Q10

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Product Description
Seller Information
Inquiry History

Description

Product Detail

Superiority

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address

1.High quality and competitive price.
2.Free sample for your evaluation.
3.Promptly delivery by well-reputed shipping lines.
4.Trial order is available for testing after samples.
5.We will inform you all the information at every stage in advance.
6.Packaging can gear to buyers' special request.

Our service

1. Reply your inquiry in 24 working hours.
2. Customized design is available. OEM are welcomed.
3. Exclusive and unique solution can be provided to our customer by our well-trained and professional engineers and
staff.
4. Professional factory: We are manufacturer, specializing in producing all kinds of herb extract for more than 10 years, competitive with good quantity.
5. As an honest seller, we always use superior raw material, advanced machines, skilled technicians to ensure our products to be finished in high quality and stable feature.

Shop High purity Semaglutide 98% with best price cas 910463-68-2 and Semaglutide raw powder-Detailed Image 1

Shop High purity Semaglutide 98% with best price cas 910463-68-2 and Semaglutide raw powder-Detailed Image 2

FAQ

1.: Are you a factory or trading company
We are the integration of factory and trade.

2.: How is the quality I want to test.
Before production and extraction, we will test all raw materials.Quality is our top priority.All products are strictly tested and confirmed by our QC and QA, approved by Third Party Lab in China.So you will be assured with Good Quality if you choose us. We welcome you test the product and hope to get your feedback.

3.: Can I get a Free sample
Yes,We can provide free samples.For most products we can provide you a free sample, You only need to pay for Shipping. Plesae be free to consult our salesman.
For a larger quantity, we always support you with better price, and we will have some discount in some especial days.

4. : What's your main payment method
T/T (Bank transfer), Wechat,Alipay,Credit card payment.

5. : Have you received my payment How long will it take
Generally, we can receive your payment the next day, and we will inform you as soon as we receive your payment.
After confirmation payment, we will send out package

6.:When will you sent out the goods after successful payment
Normally the order will be delivery within 1-3 days after the order confirmed, except the customized products.

7.:What modes of transportation do you have to choose
We cooperate with HKEMS, DHL, TNT, UPS, FEDEX, EMS, China Air Post ,sea transportation etc.
And with the SAFE SHIPPING in each country, you can receive the goods smoothly.It is fast and safe method.

8.:How long does it take to the goods arrived
It is Depending on your location:
For small order, please expect 5-7 days by DHL,UPS,TNT, FEDEX, HKEMS,Netherlands post.
For large order, please allow 5-8 days by Air, 20-35 days by Sea
At the same time, we have warehouses in Germany and California, and some orders can be sent directly from Germany or California.

9.:How is the goods packed
We usually send goods with disguise package outside and a double-layer sterile transparent bag inside.We have tried thousand of package methods, it looks serious and discreet.

10.: How can I get a discount
Our products have already given you a discount, and the price is favorable. Orders above $1,000 can enjoy 95% discount, transportation discount or additional sample products. Therefore, for larger quantities, we always support better prices.

11.: How to proceed order
Please Let me konw the product you are looking for,quantity and the destination country wihch help me to give you a right price;
After you confirm all details of order, pay money in advance and give us Shipping address.We arrange the shipment at first time after receive payment and offer after-sales service after you receive parcel.

12.:When will I receive the shipping number Where I can check status of my order
After the goods are sent out, our staff will send you the shipping number via email, online or WhatsApp ASAP.You can also check the status online on 17track.

13.:Is a signature required for the shipping?
Our shipping method requires no signature from your side upon delivery.

ECHEMI Editorial Reference

Niclosamide is an inhibitor of STAT3 with IC50 of 0.25 μM in HeLa cells and inhibits DNA replication in a cell-free assay.
Solid
Niclosamide is a secondary carboxamide resulting from the formal condensation of the carboxy group of 5-chlorosalicylic acid with the amino group of 2-chloro-4-nitroaniline. It is an oral anthelmintic drug approved for use against tapeworm infections. It has a role as a piscicide, a molluscicide, an antiparasitic agent, an anticoronaviral agent, an anthelminthic drug, an apoptosis inducer and a STAT3 inhibitor. It is a member of monochlorobenzenes, a member of salicylanilides, a C-nitro compound, a secondary carboxamide and a member of benzamides. It derives from a 5-chlorosalicylic acid.|Niclosamide is an antihelminthic used for the treatment of tapeworm infections. Helminths (worms) are multicellular organisms that infect very large numbers of humans and cause a broad range of diseases. Over 1 billion people are infected with intestinal nematodes, and many millions are infected with filarial nematodes, flukes, and tapeworms. They are an even greater problem in domestic animals. Niclosamide, once marketed in the US under the brand name Niclocide, was voluntarily withdrawn from market by Bayer in 1996.|Niclosamide is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Upon oral administration, niclosamide specifically induces degradation of the androgen receptor (AR) variant V7 (AR-V7) through the proteasome-mediated pathway. This downregulates the expression of the AR variant, inhibits AR-V7-mediated transcriptional activity, and reduces AR-V7 recruitment to the prostate-specific antigen (PSA) gene promoter. Niclosamide also prevents AR-V7-mediated STAT3 phosphorylation and activation. This inhibits AR/STAT3-mediated signaling and prevents expression of STAT3 target genes. Altogether, this may inhibit growth of AR-V7-overexpressing cancer cells. The AR-V7 variant, which is encoded by contiguous splicing of AR exons 1/2/3/CE3, is upregulated in a variety of cancer cell types, and is associated with both cancer progression and resistance to AR-targeted therapies.|An antihelmintic that is active against most tapeworms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p48)

Basic Info

Product Name:

Niclosamide

Other Name:

Benzamide,5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxy-;Salicylanilide,2′,5-dichloro-4′-nitro-;5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide;Bayluscid;5-Chloro-2′-chloro-4′-nitrosalicylanilide;N-(2-Chloro-4-nitrophenyl)-5-chlorosalicylamide;2′,5-Dichloro-4′-nitrosalicylanilide;HL 2447;2-Hydroxy-5-chloro-N-(2-chloro-4-nitrophenyl)benzamide;Iomesan;Niclosamide;Phenasal;Vermitin;Yomesan;2-Chloro-4-nitrophenylamide-6-chlorosalicylic acid;Fenasal;N-(2′-Chloro-4′-nitrophenyl)-5-chlorosalicylamide;Mansonil;Radeverm;5-Chloro-N-(2′-chloro-4′-nitrophenyl)salicylamide;Bayer 2353;Lintex;Nasemo;Sulqui;Tredemine;Sagimid;Devermin;Devermine;Cestocid;Mato;Vermitid;Helmiantin;Fedal-Telmin;BAY 2353;Zestocarp;WR 46234;Utosamide;Niclocide;Cestocide;Ruby;NSC 178296;12687-52-4

CAS No.:

50-65-7

Molecular Formula:

C13H8Cl2N2O4

InChIKeys:

InChIKey=RJMUSRYZPJIFPJ-UHFFFAOYSA-N

Molecular Weight:

327.12

Exact Mass:

327.12

EC Number:

200-056-8

UNII:

8KK8CQ2K8G

NSC Number:

758440|178296

DSSTox ID:

DTXSID7040362

NCI Thesaurus Code:

C66240

Color/Form:

PALE, YELLOW CRYSTALS|ALMOST COLORLESS CRYSTALS|A cream-colored or yellowish-white powder|Bright yellow crystalline solid

ATC Code:

P02DA01|P - Antiparasitic products, insecticides and repellents

HScode:

2924299090

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

95.2

XLogP3:

10 @ pH 9.6

Appearance:

Solid

Density:

1.6±0.1 g/cm3

Melting Point:

225-230 °C

Boiling Point:

424.5±45.0 °C at 760 mmHg

Flash Point:

210.5±28.7 °C

Refractive Index:

1.709

Water Solubility:

acetone: methanol: soluble 50mg/mL (methanol:acetone (1:1))

Storage Conditions:

0-6°C

Vapor Pressure:

<9.87X10-9 mm Hg at 20 deg C

Toxicity:

Oral-Rat LD50: 2500 mg/kg; Oral-Mouse LD50: 1000 mg/kg

Flammability characteristics:

Combustion produces toxic chloride and nitrogen oxide gases

Taste:

Tasteless

Experimental Properties:

Hydrolysed in aqueous solution with a decomposition half-life at 20 °C of 7 days (pH 6.9), 18.8 days (pH 13.3). Stable to heat. Decomposes under UV irradiation. Hydrolysed by concentrated acid or alkali.|Decomposes at 208 °C|Its biological effectiveness in water is stable at pH 5-9 and is also largely independent of the concentration of calcium and magnesium ions.

See More Niclosamide Properties 

Hazard Identification

Classification of the substance or mixture

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H400 Very toxic to aquatic life
Prevention	P273 Avoid release to the environment.
Response	P391 Collect spillage.
Storage	none
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

stored at a temp less than 30 deg C; freezing of the tablets should be avoided.

See More Niclosamide Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Estradiol,Progesterone,GS441524,4-Butylresorcinol,DeoxyArbutin,Coenzyme Q10

Location:
XINYUAN DADUHUI PHASE 1, NO.258 TAOYUAN NORTH ROAD, LIANHU DISTRICT, XI 'AN , SHAANXI CHINA

Payment Terms:
TT against copy of documents,100% TT in advance

Average lead Time:
30 days

Total Annual Revenue:
$2.5 million-$5 million

Total Employees:
11-50

Year of Establishment:
2023

Company Profile

Inquiry History

3 Inquiries

Country	Product	Purchase Quantity	Date Posted
Jordan	Niclosamide	1000 KG	Aug 29, 2024
China	Niclosamide	1 MT	Jun 18, 2026
United Kingdom	niclosamide	1 MG	Mar 6, 2026

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High purity Niclosamide 98% with best price 50-65-7 and Niclosamide raw material

Product Description

Seller Information