100% Safe customs clearance high quality Prostaglandin E1 CAS 745-65-3 with Best Price Prostaglandin E1
35 Inquiries
745-65-3
Pharmaceutical Grade
99%
深圳
Faithful
1kg/bag;25kg/Cardboard Drum
2024-06-09
Estradiol,Progesterone,GS441524,4-Butylresorcinol,DeoxyArbutin,Coenzyme Q10
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferencePG is a group of twenty-carbon straight-chain unsaturated fatty acid, arachidonic acid is usually the biosynthetic precursor, for prostate acid (prostanoic acid) is generated by enzymatic and non-enzymatic conversion , with an endogenous physiological skeleton active substance. In 1958 for the first time people obtained two pure PG crystallines from sheep seminal separation: PGE1 and PGF1α. Natural PG is classicified into three communities by structures (PG1, PG2, PG3), ten types (PGA, PGB, PGC, PGD, PGE, PGF, PGG, PGH, PGI, PGJ). E, F types in six natural PG, ie, PGE1, PGE2, PGE3 and PGF1α + PGF2α + PGF3α were earliest studied , the primary PG; A, B, C, D, G, H, I, J and other natural PG are called secondary PG. Various PG code names (such as E, F, etc.) are based on observations from the study during the early years. PG soluble in ether (ethyl) is represented by E, that is PGE, PG soluble in phosphate solution is represented by F (Swedish fosfate), namely PGF. PGA, PGB respectively are represented by PGE acid (acid) or base (base) processed end products.It is white or pale yellow needle-like crystal. Mp115-116 ℃, specific rotation-61.6 ° (c = 0.56, THF). Prostaglandin E1 is a physiologically active substance with the expansion of blood vessels and inhibit platelet aggregation, and can inhibit vascular smooth muscle cells free Ca2 +, inhibite vascular sympathetic nerve endings, release norepinephrine for vascular smooth muscle relaxation, to decrease peripheral resistance , lower blood pressure, increase coronary blood flow, reduce myocardial oxygen consumption, thereby to relieve angina and reduce the incidence of myocardial infarction and reduced infarct size. It can improve heart failure, myocardial contractility, increased cardiovascular output, improve the coronary circulation, protect the ischemic myocardium. It can effectively inhibit cholesterol formation of additional immune damage caused by atherosclerosis. It can inhibit smooth muscle cell growth and reduce plaque. Expansion of renal vessels and increase renal blood flow, regulate sodium and water balance, resulting in diuresis.
Prostaglandin E1 is an endogenous prostaglandin with vasodilatory, anti-platelet, and anti-hypertensive activities. It is in clinical use for the treatment of erectile dysfunction and the emergency management of infants with patent ductus arteriosus. It has also been used in the treatment of peripheral arterial occlusive disease (PAD).
Crystalline Solid
ChEBI: Prostaglandin E1 is a prostaglandins E. It has a role as a platelet aggregation inhibitor, a vasodilator agent, an anticoagulant and a human metabolite. It is a conjugate acid of a prostaglandin E1(1-).
PGE1, Alprostadil (Prostin VR Pediatric), is a naturally occurring prostaglandin that has found particular use in maintaining a patent (opened) ductus arteriosus in infants with congenital defects that restrict pulmonary or systemic blood flow.Alprostadil must be administered intravenously continually at a rate of approximately 0.1 μg/kg/min to maintain the patency of the ductus arteriosus until corrective surgery can be performed. Up to 80% of circulating alprostadil may be metabolized in a single pass through the lungs. Because apnea has been observed in 10% to 12% of neonates with congenital heart defects, this product should be administered only when ventilatory assistance is immediately available. Other commonly observed side effects include decreased arterial blood pressure, which should be monitored during infusion; inhibited platelet aggregation, which might aggravate bleeding tendencies; and diarrhea.Basic Info-
Product Name:
Prostaglandin E1
Other Name:Prost-13-en-1-oic acid, 11,15-dihydroxy-9-oxo-, (11a,13E,15S)-;(8S,11S,12S,13E,15R)-11,15-Dihydroxy-9-oxoprost-13-en-1-oic acid;ent-PGE1;Alprostadil (PGE1)／Prostaglandin E1;Alprostadil (PGE1);Prostaglandin E1 or AIPROSTADIL;l-3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentaneheptanoicacid;l-cyclopentaneheptanoicaci
CAS No.:745-65-3
Molecular Formula:C20H34O5
InChIKeys:GMVPRGQOIOIIMI-DWKJAMRDSA-N
Molecular Weight:354.48
BRN:5294062
EC Number:212-017-2
Color/Form:White to off-white
HScode:29375000
Categories:
Characteristics-
Density:
1.0458 (rough estimate)
Melting Point:115-116 °C
Boiling Point:407.69°C (rough estimate)
Refractive Index:1.6120 (estimate)
Water Solubility:insoluble
PKA:pKa 4.85± 0.07(H2O,t=25±0.1,I=0.1(NaCl)) (Uncertain)
Critical Temperature & Pressure:-20°C
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 3, Oral
Reproductive toxicity, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H301 Toxic if swallowed
H361 Suspected of damaging fertility or the unborn child
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Estradiol,Progesterone,GS441524,4-Butylresorcinol,DeoxyArbutin,Coenzyme Q10
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Location:
XINYUAN DADUHUI PHASE 1, NO.258 TAOYUAN NORTH ROAD, LIANHU DISTRICT, XI 'AN , SHAANXI CHINA
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Payment Terms:
TT against copy of documents,100% TT in advance
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Average lead Time:
30
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
11-50
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Year of Establishment:
2023
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Inquiry History35 Inquiries
Country Product Purchase Quantity Date Posted 
United States
Prostaglandin E1 CAS 745-65-3
1 G Aug 7, 2026 
Spain
Factory supply Pure Alprostadil powder CAS 745-65-3 Prostaglandin E1 pge1
10 G Dec 20, 2024 
Egypt
Pharmaceutical Raw Material Powder Prostaglandin E1 Alprostadil 745-65-3 99.9% powder
10 KG Oct 7, 2023 
Turkey
Pharmaceutical Raw Material Powder Prostaglandin E1 Alprostadil 745-65-3 99.9% powder
1000 G Nov 13, 2023
United States
PGE1
1 G Feb 11, 2025
United States
Alprostadil
1 MT May 12, 2026 
Brazil
alprostadil
21 G Apr 24, 2026
United States
alprostadil
10 MG Apr 20, 2026
United States
Prostaglandin E1
50 MG Mar 27, 2026 
Canada
Alprostadil
5 MT Mar 26, 2026
United States
Alprostadil
1 G Mar 17, 2026
United States
alprostadil
1 G Nov 23, 2025 
United Kingdom
alprostadil
1 KG Nov 21, 2025
United Kingdom
Alprostadil
10 MG Nov 21, 2025
United States
PGE1
10 MG Oct 7, 2025
United States
Alprostadil
10 PCS Aug 30, 2025
United States
Alprostadil
1 MG Jan 9, 2025
United States
Alprostadil
10 G Oct 23, 2024
United States
PGE1 Prostaglandin E1 cas745-65-3 Alprostadil 10mg/bottle 98% 20mg/bottle
1 G Oct 30, 2023
Canada
Factory Supply with High Quality Raw Material 99% Prostaglandin E1/PGE1 powder 83919-23-7
10 MT Oct 24, 2023 Post an enquiry for this product
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