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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Puerarin for Sale > Chinese manufacture PNQ supply Puerarin
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Chinese manufacture PNQ supply Puerarin

TDS

Unit Price:

$100/UNIT EXW

Get Latest Price
CAS No.:

3681-99-0

Grade:

Chemical Grade

Content:

99%

Brand:

Wuhan pnq

Packaging:

Aluminum foil bag

Price valid (until):

2029-11-28

Company Type:
Trader
Location:
China
Payment Terms:
100% TT in advance
Average Lead Time:
30 days
Qualification:
Main Products:

Apigenin,PQQ,NMNH

  • Product Description

  • Seller Information

  • Description
    Shop PNQ supply Best Quality Lowest Price Dietary Supplement Beta Nicotinamide Mononucleotide Nmn CAS 1094-61-7-Detailed Image 1
    Name Puerarin
    Synonyms 8-(beta-D-Glucopyranosyl-7-hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
    Molecular Structure Shop Chinese manufacture PNQ supply Puerarin-Detailed Image 2
    Molecular Formula C21H20O9
    Molecular Weight 416.38
    CAS Registry Number 3681-99-0

     

    Puerarin is a natural compound classified as an isoflavonoid, specifically an isoflavone glycoside, found primarily in the root of the kudzu vine (Pueraria lobata). Here's some information about puerarin:

    1. Chemical Structure: Puerarin has the chemical formula C21H20O9 and belongs to the isoflavone group of phytoestrogens. Its structure consists of a flavonoid backbone with a glycoside attached, specifically a β-D-glucopyranoside moiety.

    2. Biological Activities: Puerarin has been studied for its various pharmacological properties, including:

      • Vasodilation: Puerarin exhibits vasodilatory effects, which may help improve blood circulation and reduce blood pressure.
      • Antioxidant: Puerarin possesses antioxidant properties, allowing it to scavenge free radicals and reduce oxidative stress in cells and tissues.
      • Anti-inflammatory: Puerarin has anti-inflammatory effects, inhibiting the production of pro-inflammatory cytokines and mediators, thus reducing inflammation.
      • Cardioprotective: Puerarin may have cardioprotective effects by improving cardiac function, reducing myocardial injury, and protecting against ischemia-reperfusion injury.
      • Neuroprotective: Puerarin has been studied for its potential neuroprotective effects, including its ability to enhance cognitive function, protect against neuronal damage, and alleviate neurological disorders such as Alzheimer's disease.
      • Hepatoprotective: Puerarin may protect the liver from damage caused by toxins or diseases, thereby supporting liver health.
      • Antidiabetic: Puerarin has been investigated for its role in managing diabetes by improving insulin sensitivity, reducing blood glucose levels, and protecting pancreatic beta cells.
    3. Therapeutic Applications: Due to its pharmacological activities, puerarin has been studied for various therapeutic applications, including the treatment of cardiovascular diseases, neurological disorders, liver disorders, diabetes, and inflammatory conditions.

    4. Safety Considerations: Puerarin is generally considered safe when consumed from natural sources such as kudzu root. However, high doses or prolonged use of puerarin supplements may cause gastrointestinal side effects or interact with certain medications. Individuals with medical conditions or those taking medications should consult with a healthcare professional before using puerarin supplements.

    Overall, puerarin is a bioactive compound with potential health benefits, particularly in the areas of cardiovascular health, neuroprotection, liver health, and diabetes management. Further research is needed to fully elucidate its mechanisms of action and determine its therapeutic efficacy and safety in clinical settings.

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    Q1: What's your MOQ?
    A:It depends on different products,we can accept sample order or provide free sample for your test.
    Q2:How about delivery leadtime?
    A:Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)
    Q3: Is there a discount?
    A:Different quantity has different discount.
    Q4:How to start orders or make payments?
    A:Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T,or Bitcoin.
    Q5: How do you treat quality complaint?
    A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
    Q6:We don't know you at all, how can we trust you?
    A: You are always warm welcomed to visit us at any time.Before we start B2B, MIC has audited our company on-spot and approved our credit.Commitment is the No.1 Point of our Enterprise's Value.
    Q7:Do you test all your goods before delivery?
    A:Yes, we have 100% test before delivery,International Authorized Third-Party Test for the products if you need are highly welcomed.
    ECHEMI Editorial Reference
    White powder
    Puerarin, also known as pueraria flavonoids, is a kind of flavonoid glycoside extracted from the roots of Pueraria alba or Pueraria thomsonii and is also one of the main effective ingredients of Pueraria lobata. That Pueraria lobate was used to treat diseases has already been recorded in China’s ancient medical books such as Shen Nong’s Materia Medica, Treatise on Miscellaneous Diseases and Medical Dictionary.Kanzu root is widely distributed in our country and of rich resources. It has been reported that puerarin could be extracted from Pueraria lobata (Wild.) Ohwi, Radix Pueraria thomsonii, Pueraria omeiensiswanget Tang, Pueraria edulis Pamp and Pueraria phaseoloides, but the content of puerarin differs.Pueraria has a great value for nutrition and medicine and was considered the south ginseng of China. Puerarin has been widespread concerned over our country for its use of food and medicine in recent years.
    In 1959, Japanese chemist Shibata Shoji first studied the chemical production of pueraria root, indicating that isoflavones are the main active ingredients of pueraria root, including puerarin, daidzin and daidzein . Then in 2003, David Lee first total synthesized analogical puerarin . And it was in 1974 that puerarin was first extracted by Fang Qicheng and other chemists in China . Due to its strong activity of anti-cardiovascular and anti-cerebrovascular ischemia and hypoxia, expanding the coronary artery and cerebrovascular, reducing myocardial oxygen consumption, and improving myocardial systolic and microcirculation function, puerarin was approved for clinical use by the Ministry of Health in 1993.In recent years, researchers have synthesized a series of puerarin derivatives, and active research showed that the part of the puerarin derivatives has a good biological activity and bioavailability. In a new dosage form research, researchers have developed several types of dosage forms such as quickrelease solid dispersions, solid from microemulsion preparation, etc., which greatly increase the solubility of puerarin, thus improving bioavailability. In recent years,the research on crystal drug has opened up new ways for the application of puerarin.
    ChEBI: A hydroxyisoflavone that is isoflavone substituted by hydroxy groups at positions 7 and 4' and a beta-D-glucopyranosyl residue at position 8 via a C-glycosidic linkage.

    Certificates
    • Chinese manufacture PNQ supply Puerarin Certificates 1 TDS

    Basic Info
    Product Name:

    Puerarin

    Other Name:

    DAIDZEIN-8-C-GLUCOSIDE;8-GLUCOSYLDAIDZEIN;7-HYDROXY-3-[4-HYDROXYPHENYL]-1-BENZOPYRAN-4-ONE 8-[BETA-D-GLUCOPYRANOSIDE;PSYCHOSINE;PUERARIAROOT.P.E;PUERARIN EXTRACT;4H-1-Benzopyran-4-one,8-β-D-glucopyranosyl-;7-hydroxy-3-(4-hydroxyphenyl)-

    CAS No.:

    3681-99-0

    Molecular Formula:

    C21H20O9

    InChIKeys:

    HKEAFJYKMMKDOR-NCHCSYJDSA-N

    Molecular Weight:

    416.38

    Exact Mass:

    416.38

    BRN:

    64198

    EC Number:

    609-296-1

    Color/Form:

    White to Off-white

    HScode:

    29389090

    Characteristics
    λmax:

    303nm(MeOH)(lit.)

    PSA:

    157

    Physical Properties:

    Appearance: White to light-yellow crystalline powder. Solubility: Soluble in methanol, freely soluble in ethanol, slightly soluble in water, insoluble in chloroform and ether. Melting point: 187–189°C.

    XLogP3:

    0.38610

    Appearance:

    White to Off-white Powder

    Density:

    1.614±0.06 g/cm3(Predicted)

    Melting Point:

    187-189°C

    Boiling Point:

    688.0±55.0 °C(Predicted)

    Flash Point:

    281.5ºC

    Refractive Index:

    1.719

    Water Solubility:

    Soluble in DMSO or DMF. Slightly soluble in water or ethanol

    Storage Conditions:

    2-8°C

    PKA:

    6.46±0.20(Predicted)

    Critical Temperature & Pressure:

    2-8°C

    Hazard Identification

    Classification of the substance or mixture

    Skin irritation, Category 2

    Eye irritation, Category 2

    Specific target organ toxicity – single exposure, Category 3

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H315 Causes skin irritation

    H319 Causes serious eye irritation

    H335 May cause respiratory irritation

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P271 Use only outdoors or in a well-ventilated area.

    Response

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P321 Specific treatment (see ... on this label).

    P332+P317 If skin irritation occurs: Get medical help.

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P319 Get medical help if you feel unwell.

    Storage

    P403+P233 Store in a well-ventilated place. Keep container tightly closed.

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Apigenin,PQQ,NMNH

    Location:

    Room 1006, Building C6, Economic Development Wanda, Caidian District, Wuhan City, Hubei Province

    Payment Terms:

    100% TT in advance

    Average lead Time:

    30 days

    Total Annual Revenue:

    Less than $1 million

    Total Employees:

    5-10

    Year of Establishment:

    2021

    Wuhan PNQ trade located in Wuhan, China, is an innovative natural products manufacturer and supplier that offers raw powders as dietary ingredients, food and beverage additives, sports nutrition supplements.

  • Country Product Purchase Quantity Date Posted
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