99%Clarithromycin

Product：

Clarithromycin

CAS：

81103-11-9

molecular formula：

C38H69NO13

molecular weight：

747.95

melting point

217-220°C

frezeeing

86℃

specific rotation

D24 -90.4° (c = 1 in CHCl3)

density

1.1334 (rough estimate)

refractive index

-92 ° (C=1, CHCl3)

flashing point

>110°(230°F)

Storage

-20°C

solubility

Soluble in DMSO

acid(pKa)

pKa 8.99(H2O t=25.0 I=0.167) (Uncertain)

appearance

powder

colour

colorless to faint yellow

water solubility

99.48mg/L(20 ºC)

Merck

14,2339

BCS Class

4

stability

Store in Freezer

InChIKey

AGOYDEPGAOXOCK-KCBOHYOISA-N

Founded in 2008, East Chemsources Limited is a professional manufacturer of supplier in food and beverage, pharmaceuticals, cosmetics and other industries.  Through more than four years development, our company has developed from single product at first to providing solution to finished products now, is committed to providing solutions for success and growth through long term relationships. 

Currently, our products have been exported to more than 50 countries all over the world. Our service is accomplished by providing good quality solution that matches the specifications of our clients at competitive price. Our products will derive from trusted sources and arrive to our clients in time and well arranged manner, be creating the greatest benefits for our customers. 

Whether your project is large or small, whether it needs one, several or all of our disciplines you will find our level of dedication to a quality result to be the same. We are looking forward to your sincere cooperation and participation. 

Our advantages:

1. High quality with the competitive price.

2. Professional and experienced business services.

3. Prompt delivery within 2-3 weeks (1 weeks is available for ready stock)

4. Quick response to client inquiries

5. Free samples and shipping documents in accordance with the regulations of different countries

6. Adequate product inventory

6. Variety of payments, such as L/C, TT, , MoneyGram or other payments.

It is a 14-membered macrolide antibiotic. The antibacterial spectrum is the same as erythromycin and roxithromycin, etc., but it has slightly better antibacterial effect on gram-positive bacteria such as streptococcus, pneumococcus and staphylococcus, and has certain antibacterial activity on induced erythromycin resistant strains. The antibacterial effect of clarithromycin and its metabolites on influenza bacillus was enhanced. It also has a certain effect on gonococcus, Listeria, campylobacter jejuni, and has a stronger effect than erythromycin on Legionella pneumophila, mycoplasma pneumoniae, chlamydia trachomatis, ureaplasma ureolytica, etc., and has a more prominent effect in the new varieties developed in recent years, MIC90 is about 0.008 ~ 0.12mg/L. In addition, it has certain activity against spirochaeta pallidum, Mycobacterium avium, toxoplasma muris, etc., and most of them are better than other varieties. In addition to the strong antibacterial effect on anaerobic coccus, the action on fragile bacilli is better than erythromycin, etc. The antibiotic after-effect of the product on Staphylococcus aureus, Streptococcus pyogenes, influenza bacillus is obviously stronger than erythromycin. The drug is a macrolide antibiotic. Its mechanism is to inhibit the synthesis of nuclear protein by blocking the binding of nuclear protein 50S subunit. The drug has an inhibitory effect on gram-positive bacteria such as Staphylococcus aureus, streptococcus, pneumococcus, etc., and some Gram-negative bacteria such as Haemophilus influenzae, Bacillus pertussis, diplococcus gonorrhoea, Legionella pneumophila, and some anaerobic bacteria such as Bacteroides tenuis, peptostreptococcus, propionibacterium acnes, etc. In addition, it also has an inhibitory effect on mycoplasma. The antibacterial activity of this drug is similar to erythromycin in vitro, but it is stronger than erythromycin in vivo against some bacteria such as Staphylococcus aureus, streptococcus and Haemophilus influenzae. There is cross-resistance with erythromycin.