Citicoline sodium CAS NO (33818-15-4) For Sale

Neuroprotective Properties: Citicoline sodium is known for its neuroprotective effects, supporting the health and function of brain cells. It is believed to enhance cellular membrane integrity, promote the synthesis of neurotransmitters, and provide antioxidant benefits, which may help protect neurons from damage and improve cognitive function.

Enhancement of Brain Function: By increasing levels of neurotransmitters such as acetylcholine, dopamine, and norepinephrine, citicoline sodium may improve cognitive processes such as memory, attention, and learning. It is often used as a supplement to support cognitive health, particularly in aging populations and individuals with neurological conditions.

Treatment of Stroke and Brain Injury: Citicoline sodium has shown promise in clinical studies for the treatment of stroke and traumatic brain injury. It is believed to promote neural repair and regeneration, reduce inflammation, and enhance recovery of motor and cognitive functions following brain damage.

Mechanism of Action: Citicoline sodium is thought to exert its effects through multiple mechanisms, including the synthesis of phospholipids for cell membrane repair, the enhancement of cerebral blood flow and metabolism, and the modulation of neurotransmitter levels and receptor activity.

Safety and Tolerability: Citicoline sodium is generally considered safe and well-tolerated when used at recommended doses. Common side effects may include gastrointestinal discomfort, headache, insomnia, and dizziness. However, adverse reactions are rare and usually mild.

Clinical Applications: In addition to its use as a dietary supplement for cognitive support, citicoline sodium is also used in clinical settings for the treatment of neurological disorders such as Alzheimer's disease, Parkinson's disease, vascular dementia, and cognitive impairment associated with aging.

Pharmacokinetics: After oral administration, citicoline sodium is rapidly absorbed and converted into cytidine and choline in the intestine and liver. These metabolites then cross the blood-brain barrier and are incorporated into phospholipids for membrane synthesis and neurotransmitter production in the brain.

Formulations and Dosage: Citicoline sodium is available in various pharmaceutical formulations, including tablets, capsules, and injectable solutions. The recommended dosage may vary depending on the specific indication and individual patient characteristics, and it is important to follow healthcare provider guidance.

Drug Interactions: Citicoline sodium may interact with certain medications, particularly drugs that affect cholinergic or dopaminergic neurotransmission. Patients should inform their healthcare providers about all medications, supplements, and health conditions before starting citicoline sodium therapy.

Research and Development: Ongoing research is exploring the potential therapeutic applications of citicoline sodium in various neurological and psychiatric disorders, as well as its mechanisms of action and optimization of treatment strategies.