factory supply Adenosine 5'-triphosphate disodium salt / ADENOSINE 5'-TRIPHOSPHORIC ACID DISODIUM SALT CAS 987-65-5

Salt Form: ATP disodium is a salt of ATP in which the hydrogen ions associated with the phosphate groups are replaced by sodium ions. This modification increases the solubility of ATP in aqueous solutions, making it suitable for certain experimental and therapeutic applications.

Chemical Structure: Like ATP, ATP disodium consists of three phosphate groups, a ribose sugar, and an adenine base. The sodium ions are coordinated with the phosphate groups, forming a stable complex.

Biological Importance: ATP is a vital molecule in living organisms, serving as the primary energy carrier in cells. It is involved in various cellular processes, including metabolism, muscle contraction, enzyme catalysis, and cell signaling.

Energy Currency of Cells: ATP stores and transfers chemical energy within cells through the hydrolysis of its high-energy phosphate bonds. The energy released during ATP hydrolysis is used to drive endergonic reactions, such as biosynthesis and active transport, and perform mechanical work, such as muscle contraction.

ATP Hydrolysis: The hydrolysis of ATP to adenosine diphosphate (ADP) and inorganic phosphate (Pi) is catalyzed by ATPases, enzymes that couple ATP hydrolysis to various cellular processes. The released energy is used to perform cellular work or is dissipated as heat.

Regulation of Cellular Processes: ATP plays a crucial role in regulating cellular processes by controlling the activity of enzymes and ion channels through allosteric regulation and phosphorylation-mediated signaling pathways. Changes in ATP levels can signal cellular energy status and modulate cellular responses to internal and external stimuli.

Experimental Applications: ATP disodium is commonly used in experimental research as a substrate for ATP-dependent enzyme assays, energy transfer studies, and studies of cellular energetics. It is also used in biotechnology and drug discovery applications.

Therapeutic Applications: ATP disodium and related formulations have been investigated for potential therapeutic applications in various medical conditions, including wound healing, tissue regeneration, and neuroprotection. However, further research is needed to evaluate their efficacy and safety in clinical settings.

Pharmacokinetics: ATP disodium is typically administered intravenously or topically in experimental and clinical settings. Its pharmacokinetics, including absorption, distribution, metabolism, and excretion, depend on the route of administration and formulation used.

Safety Considerations: While ATP disodium is generally considered safe when used at appropriate doses for experimental or therapeutic purposes, precautions should be taken to avoid contamination and ensure proper handling and storage. Adverse effects are rare but may include local irritation at the injection site or allergic reactions in sensitive individuals.

Quality Control: ATP disodium preparations used for research or clinical purposes should undergo rigorous quality control testing to ensure purity, stability, and consistency. Analytical techniques such as high-performance liquid chromatography (HPLC) and mass spectrometry are commonly used to assess the identity, purity, and concentration of ATP disodium samples.

Storage and Stability: ATP disodium should be stored in a cool, dry place away from light and moisture to prevent degradation. Solutions of ATP disodium should be prepared freshly or stored at appropriate temperatures and pH conditions to maintain stability and activity.

Cost and Availability: ATP disodium and related formulations are commercially available from various suppliers and manufacturers. The cost and availability of ATP disodium may vary depending on factors such as purity, quantity, and source.

Research Trends: Ongoing research is focused on elucidating the mechanisms of ATP action in cellular processes, developing novel ATP-based therapeutics, and exploring the potential applications of ATP disodium in regenerative medicine, tissue engineering, and drug delivery.

Future Directions: Continued advances in our understanding of ATP biology and the development of innovative technologies for studying ATP metabolism and signaling hold promise for uncovering new therapeutic targets and strategies for treating diseases associated with cellular energy dysregulation.