Hydroxyzine dihydrochloride, CAS:2192-20-3
6 Inquiries
2192-20-3
Pharmaceutical Grade
99%
Guangzhou
BTO
kg
2029-12-31
Custom Synthetic Chemicals,Biological Stains,Pharmaceutical Intermediates,Cosmetic Grade Chemicals,Enzyme,Nucleosides
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceHydroxyzine Dihydrochloride is a histamine H1-receptor antagonist.Target: Histamine H1-ReceptorHydroxyzine inhibits carbachol (10 μM)-induced serotonin release by 34% at 10 μM, by 25% 1 μM and by 17% 0.1 μM in pretreated bladder slices for 60 min [1]. Hydroxyzine (0.1 mM) treatment inhibits the progression and severity of EAE by 50% and the extent of mast cell degranulation by 70% in Lewis rats with allergic encephalomyelitis (EAE) [2]. Hydroxyzine (500 M) significantly increases transpo
A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.
White Solid
Hydroxyzine dihydrochloride is an antihistaminic drug and a member of the diphenylmethanes family. It exerts its action by blocking the action of histamine, a substance in the body that causes allergic symptoms.Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.Basic Info-
Product Name:
Hydroxyzine dihydrochloride
Other Name:ateraxdihydrochloride;dichlorhydratede1-p.chlorbenzhydryl-4-(2-(2-hydroxyethoxy)ethyl)piperazine;neurolax;orgatrax;tran-qdihydrochloride;Disron;Hydroxyzine Hydrochloride (500 mg);Hydroxyzine Di Hcl
CAS No.:2192-20-3
Molecular Formula:C21H29Cl3N2O2
InChIKeys:ANOMHKZSQFYSBR-UHFFFAOYSA-N
Molecular Weight:447.83
Exact Mass:446.129456
EC Number:218-586-3
TSCA:TSCA listed
DSSTox ID:DTXSID5047530
Color/Form:White to Off-White
HScode:29335990
Categories:
Characteristics-
PSA:
35.9
XLogP3:4.53570
Appearance:powder
Density:1.182 g/cm3
Melting Point:190-192°C
Boiling Point:499.2°C at 760 mmHg
Flash Point:9℃
Water Solubility:H2O: solublealcohol: solublechloroform: soluble
Storage Conditions:Refrigerator
Vapor Pressure:1.17X10-11 mm Hg at 25 deg C (est)
Toxicity:LD50 in rats (mg/kg): 126 i.p.; 950 orally (Goldenthal)
Critical Temperature & Pressure:2-8°C
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
Skin irritation, Category 2
Eye irritation, Category 2
Specific target organ toxicity â single exposure, Category 3
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
Storage P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Commercially available preparations of hydroxyzine should be stored in tight, light-resistant containers at a temperature less than 40 deg C, preferably at 15 - 30 deg C; freezing of the oral solution, oral suspension, or injection should be avoided.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Custom Synthetic Chemicals,Biological Stains,Pharmaceutical Intermediates,Cosmetic Grade Chemicals,Enzyme,Nucleosides
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Location:
Room 308-80, building 1, 1963 Huaguan Road, Tianhe District, Guangzhou
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,100% TT in advance
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Average lead Time:
30
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
51-100
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Year of Establishment:
2021
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Inquiry History6 Inquiries
Country Product Purchase Quantity Date Posted 
Bangladesh
Hydroxyzine hydrochloride
1 KG Mar 16, 2026 
United States
Hydroxyzine
1 KG Mar 4, 2026 
Singapore
Hydroxyzine HCL
100 G Jul 25, 2024 
Pakistan
Hydroxyzine hydrochloride
100 KG Jun 30, 2025
Pakistan
Hydroxyzine hydrochloride
2000 KG Jul 14, 2024 
Mexico
Hydroxyzine hydrochloride
10 KG May 18, 2024 Post an enquiry for this product
