O-Desmethyl Venlafaxine
ISO
386750-22-7
Pondicherry
10 mg
2024-12-31
Drug Impurity
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceDesvenlafaxine succinate hydrate is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI).
Desvenlafaxine Succinate is a dual serotonin and norepinephrine reuptake inhibitor (SNRI) that was approved for the treatment of major depressive disorder (MDD) in the United States in 2008. In order to improve the efficacy and safety profile of venlafaxine, Wyeth discovered and developed one of the major metabolites of venlafaxine, namely the O-desmethyl metabolite (desvenlafaxine). Desvenlafaxine is also being developed for the treatment of moderate to severe vasomotor symptoms associated with menopause (i.e., hot flashes and night sweats) and is also in phase III clinical trials to study it’s effectiveness in treating fibromyalgia and neuropathic pain.
Desvenlafaxine succinate (Pristiq SR) is an extended-release tablet for oral administration that contains desvenlafaxine succinate, a structurally novel SNRI for treating MDD. Desvenlafaxine succinate is a white to off-white powder that is soluble in water. The solubility of Desvenlafaxine succinate is pH-dependent. Its octanol: aqueous system (at pH 7.0) partition coefficient is 0.21. Desvenlafaxine succinate (Pristiq SR) is available as a 50 mg extended-release tablet for oral administration. The 50 mg tablet consists of light pink, square (pyramid, one-sided), film-coated tablets debossed “W” over “50” on the flat side.CertificatesBasic Info-
Product Name:
Desvenlafaxine succinate Monohydrate
Other Name:Desvenlafaxine succinate;4-(2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl)phenol succinate hydrate;4-(2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl)phenol succinate monohydrate;2-(1-Hydroxycyclohexyl)-2-(4-hydroxyphenyl)ethyl]dimethylammonium3-carboxypropanoatemonohydrate;Desvenlafaxine succinate monohydrate;Pristiq;Unii-zb22enf0xr;Desvenlafaxine (succinate hydrate)
CAS No.:386750-22-7
Molecular Formula:C20H31NO6
InChIKeys:ORUUBRMVQCKYHB-UHFFFAOYSA-N
Molecular Weight:381.47
Exact Mass:399.226
Color/Form:White to off-white
HScode:2922504500
Categories:
Characteristics-
PSA:
119
XLogP3:2.66840
Appearance:White crystalline powde
Boiling Point:403.8ºC at 760 mmHg
Flash Point:193.2ºC
Storage Conditions:Store at +4°C
Critical Temperature & Pressure:Store at +4°C
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Drug Impurity
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Location:
No 28, 3rd Cross street, Natesan Nagar( West) Pondicherry, India - 605005
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Payment Terms:
100% TT in advance
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Average lead Time:
50
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Total Annual Revenue:
$1 million-$2.5 million
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Total Employees:
5-10
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Year of Establishment:
2012
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Certifications:
Incorportation,ISO 9001:2015
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