Torasemide
56211-40-6
Industrial Grade
99%
25kg/Cardboard Drum
Yes
2024-06-29
Dyes,Textile agent,Medical intermediate,API,Pigments,Basic Chemicals
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceTorsemide is a pyridine-sulfonyl urea type loop diuretic.Target: OthersTorasemide is a pyridine-sulfonylurea type loop diuretic mainly used in the management of edema associated with congestive heart failure. It is also used at low doses for the management of hypertension. Torsemide significantly reduced total HF readmissions (relative risk [RR]: 0.41, 95% CI: 0.28-0.61, p < 0.0001) and HF readmissions (RR: 0.53, 95% CI: 0.33-0.84, p = 0.008) as well as CV readmissions (RR: 0.77, 95% CI:
Solid
Torasemide is an N-sulfonylurea obtained by formal condensation of [(3-methylphenyl)amino]pyridine-3-sulfonic acid with the free amino group of N-isopropylurea. It is a potent loop diuretic used for the treatment of hypertension and edema in patients with congestive heart failure. It has a role as a loop diuretic and an antihypertensive agent. It is a N-sulfonylurea, an aminopyridine and a secondary amino compound. It derives from a 4-aminopyridine.|Torasemide is a high-ceiling loop diuretic. Structurally, it is a pyridine-sulfnyl urea used as an antihypertensive agent. On the FDA records, torasemide was developed and first introduced by the company Teva Pharmaceuticals and FDA approved in 2002. However, torasemide was first approved for clinical use by the FDA on 1993.|Torsemide is a Loop Diuretic. The physiologic effect of torsemide is by means of Increased Diuresis at Loop of Henle.|Torsemide is an anilinopyridine sulfonylurea belonging to the class of loop diuretics. Torsemide has a prolonged duration of action compared to other loop diuretics, is extensively protein bound in plasma and has a relatively long half-life.|A pyridine and sulfonamide derivative that acts as a sodium-potassium chloride symporter inhibitor (loop diuretic). It is used for the treatment of EDEMA associated with CONGESTIVE HEART FAILURE; CHRONIC RENAL INSUFFICIENCY; and LIVER DISEASES. It is also used for the management of HYPERTENSION.Basic Info-
Product Name:
Torasemide
Other Name:3-Pyridinesulfonamide,N-[[(1-methylethyl)amino]carbonyl]-4-[(3-methylphenyl)amino]-;N-[[(1-Methylethyl)amino]carbonyl]-4-[(3-methylphenyl)amino]-3-pyridinesulfonamide;Torasemide;AC 4464;BM 02015;Torsemide;Luprac;Demadex;Torem;Toradiur;Unat;JDL 464;BM 02.015;Dilutol;Tide 10;Examide;1-([4-[(3-Methylphenyl)amino]pyridin-3-yl]sulfonyl)-3-(propan-2-yl)urea;1-[4-(3-Methylanilino)pyridin-3-yl]sulfonyl-3-propan-2-ylurea;UpCard;Isemid
CAS No.:56211-40-6
Molecular Formula:C16H20N4O3S
InChIKeys:InChIKey=NGBFQHCMQULJNZ-UHFFFAOYSA-N
Molecular Weight:348.42000
Exact Mass:348.42
UNII:W31X2H97FB
DSSTox ID:DTXSID2023690
NCI Thesaurus Code:C29506
ATC Code:QC03CA04|C03CA04|C - Cardiovascular system
HScode:2935009090
Categories:
Characteristics-
PSA:
108.57000
XLogP3:2.7
Appearance:Solid
Density:1.283 g/cm3
Melting Point:163-164 °C
Refractive Index:1.594
Water Solubility:Water soluble
Storage Conditions:Store in original container in a cool dark place.
PKA:7.1None
Dissociation Constants:7.1
Hazard IdentificationClassification of the substance or mixture
Eye irritation, Category 2
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Warning
Hazard statement(s) H319 Causes serious eye irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Storage none
Disposal none
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Dyes,Textile agent,Medical intermediate,API,Pigments,Basic Chemicals
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Location:
Room 507, Dongnan Technology R&D Center, No.438 Jincheng Road, Beigan Street, Xiaoshan District,Hangzhou City,Zhengjiang Province,China
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Payment Terms:
TT against copy of documents,L/C,100% TT in advance
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Average lead Time:
20 days
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Total Annual Revenue:
$25 million-$50 million
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Total Employees:
51-100
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Year of Establishment:
2013
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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