Torsemide(Demadex)
56211-40-6
98%
2026-06-29
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName Torsemide(Demadex) Cat No CEI-0388 Description Torsemide(Demadex) is a pyridine-sulfonyl urea type loop diuretic with an IC50 of 2.7 uM. Furosemide is the most widely prescribed loop diuretic in the setting of systolic heart failure (HF), yet torsemide has been shown to have less inter- and intra-individual variation in bioavailability and a longer duration of action compared with furosemide. Compared to furosemide, torsemide significantly reduces total HF readmissions and HF readmissions as well as CV readmissions in patients with "at least 1 readmission." Compared with furosemide, torsemide significantly reduces HF and CV-related hospital readmissions in systolic HF. Torsemide inhibits aldosterone secretion by adrenal cells from rats, cows, and guinea pigs stimulated in vitro by potassium, angiotensin, dibutyryl cyclic AMP, ACTH, or corticosterone. Inhibitory concentrations for adrenal cells (micromolar) were comparable with those reported to inhibit ion transport in isolated renal tubules. Alias Demadex CAS No 56211-40-6 Molecular Weight 348.42 Purity >98% Storage 2 years -20centigrade Powder Synonyms Demadex Targets HF Molecular Formula C16H20N4O3S Solubility DMSO 1 mg/mL,Water category Circulatory System Drugs(c1427) cas_num 56211-40-6 Basic Info-
Product Name:
Torasemide
Other Name:3-Pyridinesulfonamide,N-[[(1-methylethyl)amino]carbonyl]-4-[(3-methylphenyl)amino]-;N-[[(1-Methylethyl)amino]carbonyl]-4-[(3-methylphenyl)amino]-3-pyridinesulfonamide;Torasemide;AC 4464;BM 02015;Torsemide;Luprac;Demadex;Torem;Toradiur;Unat;JDL 464;BM 02.015;Dilutol;Tide 10;Examide;1-([4-[(3-Methylphenyl)amino]pyridin-3-yl]sulfonyl)-3-(propan-2-yl)urea;1-[4-(3-Methylanilino)pyridin-3-yl]sulfonyl-3-propan-2-ylurea;UpCard;Isemid
CAS No.:56211-40-6
Molecular Formula:C16H20N4O3S
InChIKeys:InChIKey=NGBFQHCMQULJNZ-UHFFFAOYSA-N
Molecular Weight:348.42000
Exact Mass:348.42
UNII:W31X2H97FB
DSSTox ID:DTXSID2023690
NCI Thesaurus Code:C29506
ATC Code:QC03CA04|C03CA04|C - Cardiovascular system
HScode:2935009090
Categories:
Characteristics-
PSA:
108.57000
XLogP3:2.7
Appearance:Solid
Density:1.283 g/cm3
Melting Point:163-164 °C
Refractive Index:1.594
Water Solubility:Water soluble
Storage Conditions:Store in original container in a cool dark place.
PKA:7.1None
Dissociation Constants:7.1
Hazard IdentificationClassification of the substance or mixture
Eye irritation, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H319 Causes serious eye irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Storage none
Disposal none
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
