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5-Hydroxytryptophan, 5 HTP, CAS NO: 4350-09-8

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CAS No.:

4350-09-8

Grade:

Food Grade

Content:

98%

Port:

SHANGHAO

Packaging:

25KG

Price valid (until):

2024-06-29

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SHANHAI YUKING+POVIDONE

Company Type:

Trader

Location:

China

Qualification:

Main Products:

EXCIPIENTS,POVIDONE,AMINO ACIDS,API,VITAMINS

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Product Description
Seller Information
Inquiry History

Description

Product Detail

5-Hydroxytryptophan Details

The serotonin levels in the body are associated with the regulation of sleep, mood, and appetite. A balanced serotonin level has been shown to support restful sleep, good mood, and decreased sugar cravings.* There are several ways to support a healthy serotonin level. L-tryptophan and 5-Hydroxytryptophan (5-HTP) are both precursors to serotonin. However, supplementation with 5-HTP is preferable, because unlike L-tryptophan, 5-HTP cannot be shunted into other uses in the body, such as niacin or protein production. 5-HTP is well absorbed by the body and easily crosses the blood-brain barrier where it can increase the synthesis of serotonin in the central nervous system.* And 5-HTP can be taken with meals without reducing its effectiveness.*

5-Hydroxytryptophan (5-HTP) is the intermediate metabolite the body produces when it initiates the process of converting the essential amino acid L-tryptophan to serotonin. Therefore, supplementation with 5-HTP will bypass the conversion of L-tryptophan into 5-HTP by the enzyme tryptophan hydroxylase – which is the rate-limiting step in the synthesis of serotonin – and is a conversion that can be inhibited by a number of factors, including stress, insulin resistance, increasing age, and deficiencies of vitamin C, folate, and iron.* 5-HTP is well absorbed when taken orally, with about 70 percent going into the bloodstream.* Intestinal absorption of 5-HTP does not require the presence of a transport molecule, and its absorption is not affected by the presence of other amino acids; therefore, 5-HTP can be taken with meals without reducing its effectiveness. 5-HTP has been shown to have a beneficial impact on mood, sleep, carbohydrate cravings, and discomfort associated with fatigue.* Numerous studies of individuals with negative mood status have shown significant positive response with 50-300 mg of 5-HTP daily.*

To further facilitate serotonin production, Thorne's 5-HTP formula contains pyridoxal 5'-phosphate, the active form of vitamin B6 and the necessary cofactor for the conversion of 5-HTP to serotonin. 5-HTP is commercially produced by extraction from the seeds of the African plant, Griffonia simplicifolia.

Each lot is thoroughly tested for contaminants, including Peak X, and is Peak X free.

Items	Specifications

Certificates

Basic Info

Product Name:

L-5-Hydroxytryptophan

Other Name:

5-hydroxy-l-tryptopha;pretonine;L-2-AMINO-3-(5-HYDROXYINDOLYL)PROPIONIC ACID;L-5-HYDROXYTRYPTOPHAN HYDRATE;L-5-HYDROXYTRYPTOPHAN;2-AMINO-3-(5-HYDROXY-1H-INDOL-3-YL)PROPIONIC ACID;(-)-5-HYDROXY-L-TRYPTOPHAN;5-HYDROXY-L-TRP-OH

CAS No.:

4350-09-8

Molecular Formula:

C11H12N2O3

InChIKeys:

LDCYZAJDBXYCGN-VIFPVBQESA-N

Molecular Weight:

220.22

Exact Mass:

220.22

BRN:

88200

EC Number:

224-411-1

UNII:

C1LJO185Q9

UN Number:

2811

TSCA:

TSCA listed

DSSTox ID:

DTXSID1025437

NCI Thesaurus Code:

C52181

Color/Form:

white

ATC Code:

N - Nervous system

HScode:

29339990

Categories:

Nutrition Supplements

Characteristics

PSA:

99.3

XLogP3:

-2.051

Appearance:

white solid

Density:

0.902 g/mL at 25 °C (lit.)

Melting Point:

270 °C (dec.) (lit.)

Boiling Point:

361.16°C (rough estimate)

Flash Point:

175 °F

Refractive Index:

n20/D1.4850(lit.)

Water Solubility:

Slightly soluble

Storage Conditions:

2-8°C

Vapor Pressure:

2.55X10-11 mm Hg at 25 deg C (est)

Specific rotation:

-32.5 º (c=1,H2O on dry basis)

PKA:

2.22±0.10(Predicted)

Henrys Law Constant:

Henry's Law constant = 2.1X10-18 atm-cu m/mol at 25 °C (est)

Collision Cross Section:

152.2 Å² [M+Na]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|148.86 Å² [M-H]- [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|157.88 Å² [M+H]+ [CCS Type: DT, Method: stepped-field]|156.47 Å² [M+Na]+ [CCS Type: DT, Method: stepped-field]|153.72 Å² [M-H]- [CCS Type: DT, Method: stepped-field]|149.8 Å² [M-2H+Na]-

Experimental Properties:

Hydroxyl radical reaction rate constant = 2.39X10-10 cu cm/molec-sec at 25 °C (est)|Crystals; specific optical rotation: -32.5 deg at 20 °C/D (water); +16.0 deg at 20 °C/D (4 N HCl) /l-form/|Crystals; specific optical rotation: +32.2 deg at 20 °C/D (water) /d-form/

Air and Water Reactions:

L-5-Hydroxytryptophan is sensitive to air. Slightly water soluble .

Reactive Group:

Phenols and Cresols

Reactivity Profile:

L-5-Hydroxytryptophan reacts with bases. .

Critical Temperature & Pressure:

2-8°C

See More L-5-Hydroxytryptophan Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 3, Oral

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H301 Toxic if swallowed
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product.
Response	P301+P316 IF SWALLOWED: Get emergency medical help immediately. P321 Specific treatment (see ... on this label). P330 Rinse mouth.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More L-5-Hydroxytryptophan Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
EXCIPIENTS,POVIDONE,AMINO ACIDS,API,VITAMINS

Location:
5th Floor, No.35, Lane 100, Banxia Rd. Pudong New District, Shanghai

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
180

Total Annual Revenue:
$25 million-$50 million

Total Employees:
51-100

Year of Establishment:
2005

SHANHAI YUKING+POVIDONE is a leading Trader supplier of L-Ascorbic acid, Glycine, Sodium saccharin based in Districts, Shanghai, China. With a commitment to quality and customer satisfaction, SHANHAI YUKING+POVIDONE has become a trusted name in the industry. Our product line includes a range of high-quality L-Ascorbic acid, Glycine, Sodium saccharin, which are available at competitive prices. SHANHAI YUKING+POVIDONE has established itself as a reliable supplier of chemical products on the echemi.com.

Inquiry History

1 Inquiries

Country	Product	Purchase Quantity	Date Posted
South Korea	5-HTP/5-hydroxytryptophan 30% White powder S15 BLRH/VDK	5 KG	Dec 1, 2025

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