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Fosaprepitant dimeglumine cas265121-04-8 White like white powder solid

Name: Fosaprepitant dimeglumine cas265121-04-8 White like white powder solid
Brand: AIRUIKE
SKU: pr2406171521
Price: 100 USD
Availability: InStock

Unit Price: Get Latest Price 

CAS No.:

265121-04-8

Grade:

Pharmaceutical grade

Content:

99%

Port:

QINGDAO

Brand:

AIRUIKE

Packaging:

25kg/Cardboard Drum

Price valid (until):

2025-10-10

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Shandong Airuike Chemical Co., Ltd.

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents,D/P,D/A,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

15 days

Qualification:

Main Products:

api,Intermediates,Organic Chemistry,Inorganic Chemistry,Daily Chemicals,Cosmetic Raw Materals

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Product Description
Seller Information

Description

FAQ

Q : What is your terms of payment?
A : T/T 30% as deposit, and 70% before delivery or 100% L/C at sight.
Q : How to confirm the Product Quality before placing orders?
A : You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

Q : How about the delivery time?
A : Within 7 days after payment confirmation. (excluding Chinese holidays)

Q : What documents did you provide?
A :We usually provide commercial invoice, packing list, shipping list, waybill, health certificate and certificate of origin. If
there are any special requirements in your market, please let us know.Some technical paperwork is available, such as COA, HNMR, HPLC, LC-MS etc.

Q: How do you deal with quality complaints?
A : First of all, our quality control will ensure our quality. If we cause real quality problems, we will once again provide good
products or refund your losses.

Q : How do you make our business long-term and good relationship?
A : 1. We keep good quality and competitive price to ensure our customers benefit;
2. We respect every customer as our friend and we sincerely do business and make friends with them, no matter where they come from

Q : Do you have stock?
A: Yes, we have all our products in stock. Our annual output is 200 tons. No matter when you order, we will ship within 1 to 3 days.
Q : Why should I choose you?
A: Powerful technical support-come from our highly skilled & fully experienced staff, working in chemical industry for over
5years, in average.Strict quality control-comes form our sophisticated management system.Professional and warm sales team-since we
believe we can only win via our hard work in a competitive worldQuick response and excellent presale and after sale service-since
we believe our customers deserve all the best service.
Q : Can I get best price from you?
A: Of course. We don't chase excessive profits and alway

Q : What is your terms of payment?
A : T/T 30% as deposit, and 70% before delivery or 100% L/C at sight.
Q : How to confirm the Product Quality before placing orders?
A : You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

Q : How about the delivery time?
A : Within 7 days after payment confirmation. (excluding Chinese holidays)

Q : What documents did you provide?
A :We usually provide commercial invoice, packing list, shipping list, waybill, health certificate and certificate of origin. If
there are any special requirements in your market, please let us know.Some technical paperwork is available, such as COA, HNMR, HPLC, LC-MS etc.

Q: How do you deal with quality complaints?
A : First of all, our quality control will ensure our quality. If we cause real quality problems, we will once again provide good
products or refund your losses.

Q : How do you make our business long-term and good relationship?
A : 1. We keep good quality and competitive price to ensure our customers benefit;
2. We respect every customer as our friend and we sincerely do business and make friends with them, no matter where they come from

Q : Do you have stock?
A: Yes, we have all our products in stock. Our annual output is 200 tons. No matter when you order, we will ship within 1 to 3 days.
Q : Why should I choose you?
A: Powerful technical support-come from our highly skilled & fully experienced staff, working in chemical industry for over
5years, in average.Strict quality control-comes form our sophisticated management system.Professional and warm sales team-since we
believe we can only win via our hard work in a competitive worldQuick response and excellent presale and after sale service-since
we believe our customers deserve all the best service.
Q : Can I get best price from you?
A: Of course. We don't chase excessive profits and alway

ECHEMI Editorial Reference

Fosaprepitant dimeglumine belongs to the group of antiemetics. The active substance inhibits part of the vomiting centre. It is used for the treatment of postoperative or chemotherapyinduced nausea and vomiting.
Fosaprepitant dimeglumine is a white to off-white amorphous powder. It is freely soluble in water. The pH of a 1.0 g sample of fosaprepitant dimeglumine, dissolved in 25 mL of water, is approximately 8.3. Fosaprepitant, a prodrug of aprepitant, when administered intravenously is rapidly converted to aprepitant.
ChEBI: Fosaprepitant dimeglumine is an organoammonium salt obtained by reaction of fosaprepitant with two equivalents of 1-deoxy-1-(methylamino)-D-glucitol. A substance P/neurokinin 1 (NK1) receptor antagonist. Aprepitant is a selective high-affinity antagonist of human substance P/neurokinin 1 (NK1) receptors. Aprepitant has little or no affinity for serotonin (5-HT3), dopamine, and corticosteroid receptors, the targets of existing therapies for chemotherapy-induced nausea and vomiting and postoperative nausea and vomiting It has a role as a prodrug, an antiemetic and a neurokinin-1 receptor antagonist. It contains a fosaprepitant(2-).

Basic Info

Product Name:
Fosaprepitant dimeglumine

Other Name:
Phosphonic acid, (3-(((2R,3S)-2-((1R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)-4-morpholinyl)methyl)-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl)-, compd. with 1-deoxy-1-(methylamino)-D-glucitol (1:2);Unii-D35fm8T64x;[3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-Morpholinyl]Methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]phosphonate 1-Deoxy-1-(MethylaMino)-D-glucitol;1-Deoxy-1-(MethylaMino)-D-glucitol [3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-Morpholinyl]Methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]phosphonate;1-DEOXY-1-(METHYLAMINO)-D-GLUCITOL [[(2R,3S]-2-[(1R)-1-[3,5-BIS (TRIFLUOROMETHYL)PHENYL] PHENYL]ETHOXY]-(4-FLUOROPHENYL);3-[2(R)-[1(R)-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3(S)-(4-fluorophenyl)Morpholin-4-ylMethyl]-5-oxo-4,5-dihydro-1H-1,2,4-triazole-1-phosphinic acid bis(N-Methyl-D-glucaMine) salt;Fosaprepitant diMegluMine salt;Fosaprepitant dimeglumine, >=99%

CAS No.:
265121-04-8

Molecular Formula:
C30H39F7N5O11P

InChIKeys:
UGJUJYSRBQWCEK-QBRZKSSTNA-N

Molecular Weight:
809.63

Exact Mass:
1004.33786385

EC Number:
682-419-4

DSSTox ID:
DTXSID50181095

Color/Form:
White to off-white

ATC Code:
A04AD12

Categories:
Bulk Drug Intermediates

Characteristics

Water Solubility:
H2O: 2mg/mL, clear

PKA:
Fosaprepitant dimeglumine has four functional groups which have pKa values of 3.05 ± 0.03, 4.92 ± 0.02, 9.67 ± 0.01 and 10.59 ± 0.03. The pka value of 3.05 corresponds to the morpholinium group, the pka of 4.92 corresponds to the monophosphonate group, the pka of 9.67 corresponds to the meglumine counter ion, and the pka of 10.59 corresponds to the triazolinone NH group.

Critical Temperature & Pressure:
Sealed in dry,Store in freezer, under -20°C

See More Fosaprepitant dimeglumine Properties 
Seller Information

Business Type:
Trader

Main Products:
api,Intermediates,Organic Chemistry,Inorganic Chemistry,Daily Chemicals,Cosmetic Raw Materals

Location:
Huangdao District, Qingdao City, Shandong Province (formerly Room 606-2, Building 1, No. 10 Beijing Road, Jiaonan City)

Payment Terms:
TT against copy of documents,D/P,D/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
15 days

Total Annual Revenue:
$5 million-$10 million

Total Employees:
51-100

Year of Establishment:
2023

Company Certificates
- Credit rating certificate
- Hazardous Chemicals Business License
Company Profile
Foucsing on chemical industry,Shandong Airuike Chemical Co., LTD was established in the year 2013 and since then devoted all its efforts on how to bring best products and services to every customer,with intergrated sources and creative minds.
We are offering the market with Organic chemicals, Inorganic chemicals, Organic intermediates and water treatment products.
In construction industry,our furan resin product is high-light for metal casting as well as anticorrosion projecting for new chemical plant construction and repairing works.
Your consistent trust is our infinite power to move forward. Shandong Airuike Chemical Co., LTD never stop its step on technical researching,quality supervising,effective logistic arranging and on time services to fully satisfy customers requests. We also extended our product range by close cooperating with famous producers all around China,around the world.
By now we have established business relationship with more than 200 customers around the world.
Like our company motto says,”Innovation as power,quality as life,be honest people practical development”,Shandong Airuike Chemical Co., LTD team always put sincerity and honesty in the first place and in return customers trust us and develop win-win cooperation betwwen each other.
You’re always welcomed to contact us and share your needs,let us give you an unique satisfying for our business cooperation together.
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Fosaprepitant dimeglumine cas265121-04-8 White like white powder solid

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