cas72432-03-2 Miglitol
72432-03-2
Pharmaceutical Grade
99%
SHANGHAI
airuike
25kg/Cardboard Drum
Yes
2025-06-20
api,Intermediates,Organic Chemistry,Inorganic Chemistry,Daily Chemicals,Cosmetic Raw Materals
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Product Details
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Seller Information
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DescriptionECHEMI Editorial ReferenceMiglitol is an oral anti-diabetic drug that acts by inhibiting the ability of the patient to breakdown complex carbohydrates into glucose.Target: OthersMiglitol is an oral anti-diabetic drug that acts by inhibiting the ability of the patient to breakdown complex carbohydrates into glucose. It is primarily used in diabetes mellitus type 2 for establishing greater glycemic control by preventing the digestion of carbohydrates (such as disaccharides, oligosaccharides, and polysaccharides) in
Solid
Miglitol is a member of piperidines.|Miglitol inhibits the breakdown complex carbohydrates into glucose. It is primarily used in diabetes mellitus type 2 for establishing greater glycemic control by preventing the digestion of carbohydrates (such as disaccharides, oligosaccharides, and polysaccharides) into monosaccharides which can be absorbed by the body. Miglitol should be taken at the start of a meal for maximal effect and the effect will depend on the amount of poly and oligosaccharides in the diet. Miglitol inhibits alpha-glucosidase, making less sugars available for digestion and reducing postprandial hyperglycemia. Unlike other drugs of the same class, miglitol is not metabolized and the unmetabolized drug is excreted by the kidneys.|Miglitol is an alpha-Glucosidase Inhibitor. The mechanism of action of miglitol is as an alpha Glucosidase Inhibitor.|Miglitol is an alpha glucosidase inhibitor which delays intestinal absorption of carbohydrates and is used as an adjunctive therapy in the management of type 2 diabetes. Miglitol has not been linked to instances of clinically apparent acute liver injury.|Miglitol is a desoxynojirimycin derivative and inhibitor of alpha-glucosidase with antihyperglycemic activity. Miglitol binds to and inhibits alpha-glucosidase, an enteric enzyme found in the brush border of the small intestines that hydrolyzes oligosaccharides and disaccharides into glucose and other monosaccharides. This prevents the breakdown of larger carbohydrates into glucose and decreases the rise in postprandial blood glucose levels. Compared to acarbose, miglitol is systemically absorbed.Basic Info-
Product Name:
Miglitol
Other Name:3,4,5-Piperidinetriol,1-(2-hydroxyethyl)-2-(hydroxymethyl)-,(2R,3R,4R,5S)-;3,4,5-Piperidinetriol,1-(2-hydroxyethyl)-2-(hydroxymethyl)-,[2R-(2α,3β,4α,5β)]-;(2R,3R,4R,5S)-1-(2-Hydroxyethyl)-2-(hydroxymethyl)-3,4,5-piperidinetriol;BAY-m 1099;Miglitol;N-(2-Hydroxyethyl)moranoline;BAY 1099;N-(2-Hydroxyethyl)-1-deoxynojirimycin;Glyset;Diastabol;Seibule;(2R,3R,4R,5S)-1-(2-Hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol;Plumarol;N-(2-Hydroethyl)deoxynojirimycin;Miglitose
CAS No.:72432-03-2
Molecular Formula:C8H17NO5
InChIKeys:InChIKey=IBAQFPQHRJAVAV-ULAWRXDQSA-N
Molecular Weight:207.22
Exact Mass:207.22
EC Number:276-661-6
UNII:0V5436JAQW
DSSTox ID:DTXSID0023323
NCI Thesaurus Code:C61847
Color/Form:White to pale-yellow powder|Crystals from ethanol
ATC Code:A - Alimentary tract and metabolism
HScode:29333990
Categories:
Characteristics-
PSA:
104
XLogP3:-2.6
Density:1.5±0.1 g/cm3
Melting Point:114 °C
Boiling Point:453.7°C at 760 mmHg
Flash Point:284.3±27.4 °C
Refractive Index:1.598
Water Solubility:H2O: soluble
Storage Conditions:-20°C Freezer
Vapor Pressure:7.33X10-10 mm Hg at 25 deg C (est)
Henrys Law Constant:Henry's Law constant = 4.34X10-15 atm-cu m/mol at 25 °C (est)
Dissociation Constants:5.9|pKa = 5.9
Collision Cross Section:141 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Experimental Properties:Hydroxyl radical reaction rate constant = 1.54X10-10 cu cm/molec-sec at 25 °C (est)
Hazard IdentificationClassification of the substance or mixture
Skin irritation, Category 2
Eye irritation, Category 2
Reproductive toxicity, Category 2
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Warning
Hazard statement(s) H315 Causes skin irritation
H319 Causes serious eye irritation
H361 Suspected of damaging fertility or the unborn child
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P203 Obtain, read and follow all safety instructions before use.
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store at 25 deg C (77 deg F); excursions permitted to 15 deg -30 deg C (59 deg -86 deg F).
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Seller Information
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Business Type:
Trader
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Main Products:
api,Intermediates,Organic Chemistry,Inorganic Chemistry,Daily Chemicals,Cosmetic Raw Materals
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Location:
Huangdao District, Qingdao City, Shandong Province (formerly Room 606-2, Building 1, No. 10 Beijing Road, Jiaonan City)
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Payment Terms:
TT against copy of documents,D/P,D/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
15 days
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
51-100
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Year of Establishment:
2023
Company Certificates-
Credit rating certificate
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Hazardous Chemicals Business License
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