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Anti-Diabetic API 99% Purity Gliclazide Powder CAS 21187-98-4

Name: Anti-Diabetic API 99% Purity Gliclazide Powder CAS 21187-98-4
Brand: TNJONE
SKU: pr2406251170
Price: 80 USD
Availability: InStock

8 Inquiries

Unit Price:

$80-90/KG FOB

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CAS No.:

21187-98-4

Grade:

Pharmaceutical Grade

Content:

99%

Port:

china any port

Brand:

TNJONE

Packaging:

1kg,25kgor according to customer's detail requirement.

Price valid (until):

2028-12-31

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Shaanxi TNJONE Pharmaceutical Co., Ltd

Company Type:

Manufactory

Location:

China

Payment Terms:

TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

5 days

Qualification:

Main Products:

Semaglutide,Tirzepatide,API,Vitamins,Food Additive

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Product Description
Seller Information
Inquiry History

Description

Anti-Diabetic API 99% Purity Gliclazide Powder CAS 21187-98-4

What is Gliclazide?

Gliclazide is a 2nd generation oral sulfonylurea hypoglycemic agent with strong action. Its mechanism is similar to that of toluenosulfonylurea, i.e., it selectively acts on pancreatic β-cells to promote insulin secretion and enhance insulin release after eating glucose, which can not only improve the metabolism of diabetic patients, but also improve or delay the occurrence of diabetic vascular complications.
Gliclazide is mainly used for mild and moderate type II diabetes mellitus with adult-onset where diet and exercise control alone are ineffective and without a tendency to ketosis, and also improves fundus lesions and metabolic and vascular dysfunctions in diabetic patients.

Items	Specifications
Product Name	Gliclazide
Cas No	21187-98-4
Einecs	244-260-5
MF	C15H21N3O3S
MW	323.41
Melting Point	163-169 °C (lit.)
Appearance	White powder
Shelf Life	2 Years When Properly Stored
Storage	Keep in a cool, dry, dark location in a tightly sealed container or cylinder.

Shop Anti-Diabetic API 99% Purity Gliclazide Powder CAS 21187-98-4-Detailed Image 1

Specification

Test	Specifications	Results of analysis
Appearance	White or almost white powder.	White powder
Solubility	Practically insoluble in water; freely soluble in methylene chloride; sparingly soluble in acetone; slightly soluble in ethanol(96 percent).	Meets the requirements
Identifications	The infrared absorption spectrum is concordant with that obtained with gliclazide CRS.	Meets the requirements
Impurity B (By HPLC)	≤2ppm	0.5ppm
Heavy metals	≤10ppm	<10ppm
Related substances (By HPLC)	Impurity F ≤0.1%	Non-detected
	Each unspecified impurity ≤0.10%	0.04%
	Sum of impurities other than F ≤0.2%	0.11%
Loss on drying	≤0.25%	0.11%
Sulfated ash	≤0.1%	0.03%
Residual solvents (By GC)	Ethyl acetate NMT 2500 ppm	265ppm
Residual solvents (By GC)	N,N-Dimethylformamide NMT 880 ppm	Non-detected
Assay	99.0-101.0%, on dried basis.	100.0%

Function

Application
1. For adults with type 2 diabetes, diabetes associated with obesity or vascular lesions.
2. Hypoglycemic agents. It can be used for the treatment of non- dependent diabetes mellitus.
3. Hypoglycemic agents, non-dependent diabetes mellitus.

Company Information

Shaanxi TNJONE Pharmaceutical Technology Co., LTD., located in the beautiful ancient capital of Xi 'an, is committed to pharmaceutical raw materials, kill varieties, food and feed additives, chemical reagents, plant extracts and other fields, the enterprise adhering to provide customers with quality service, supply high-quality products. Our company after careful planning, hard study, gradually formed a complete service system, based on the domestic and foreign raw materials market special development. Make the raw materials industry bigger and stronger, and serve the vast number of new and old customers. With "world peace and health" as its responsibility, the company adheres to the service concept of "meeting all requirements of customers for products", and guarantees the service principle of "providing qualified products", so that you can get the "God-like" noble shopping enjoyment. Our company has more than 500 kinds of raw materials inventory at any time to meet the various needs of customers for products. The company's products all comply with the relevant national regulations, from the smallest packaging to tons of goods are available. Is your choice of raw materials the best partner.

Shaanxi TNJONE Pharmaceutical Technology Co., Ltd. is willing to rely on the rapid development of e-commerce and national policy support of the good environment background, nesting, welcome people from all walks of life to visit our company, exchange, and seek common development, looking forward to sharing with you, win-win, to realize the dream.

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FAQ

1.How to get in touch with us?

You can chat with us by Trademanager,WhatsApp or simply giving us an email, a phone call. All our contacts information can be found from our website.

2.Are you a manufacturer or trade company?

We are a professional manufacturer.

3.Can I get a sample?

Yes, free sample can be provided, but shipping cost is covered by your side.

4.What's your MOQ?

It is based on the different product. Some are 1g while some are 1 kg. Please be free to consult our salesman.

5.When can I get the quotation?
We usually quote within 1 hours after we get your inquiry. If it's a urgent order you can call us or mention it in your email subject, and we can take it as priority.

6.Is there any discount?
Yes, some products are applied for discount, but it depends on the quantity.

7.Can you do OEM for me?
Yes,we accept OEM orders, just contact us and give us your requirement. We will offer you a reasonable price and make samples ASAP.

ECHEMI Editorial Reference

White Cyrstalline Solid
Solid
Gliclazide is a N-sulfonylurea. It has a role as a hypoglycemic agent, a radical scavenger and an insulin secretagogue.|Gliclazide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It has been classified differently according to its drug properties in which based on its chemical structure, gliclazide is considered a first-generation sulfonylurea due to the structural presence of a sulfonamide group able to release a proton and the presence of one aromatic group. On the other hand, based on the pharmacological efficacy, gliclazide is considered a second-generation sulfonylurea which presents a higher potency and a shorter half-life. Gliclazide belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin. Sulfonylureas increase both basal insulin secretion and meal-stimulated insulin release. Medications in this class differ in their dose, rate of absorption, duration of action, route of elimination and binding site on their target pancreatic β cell receptor. Sulfonylureas also increase peripheral glucose utilization, decrease hepatic gluconeogenesis and may increase the number and sensitivity of insulin receptors. Sulfonylureas are associated with weight gain, though less so than insulin. Due to their mechanism of action, sulfonylureas may cause hypoglycemia and require consistent food intake to decrease this risk. The risk of hypoglycemia is increased in elderly, debilitated and malnourished individuals. Gliclazide has been shown to decrease fasting plasma glucose, postprandial blood glucose and glycosolated hemoglobin (HbA1c) levels (reflective of the last 8-10 weeks of glucose control). Gliclazide is extensively metabolized by the liver; its metabolites are excreted in both urine (60-70%) and feces (10-20%).|An oral sulfonylurea hypoglycemic agent which stimulates insulin secretion.

Basic Info

Product Name:

Gliclazide

Other Name:

Benzenesulfonamide,N-[[(hexahydrocyclopenta[c]pyrrol-2(1H)-yl)amino]carbonyl]-4-methyl-;Urea,1-(hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)-;Cyclopenta[c]pyrrole,benzenesulfonamide deriv.;N-[[(Hexahydrocyclopenta[c]pyrrol-2(1H)-yl)amino]carbonyl]-4-methylbenzenesulfonamide;Gliclazide;Diamicron;S 1702;1-(Hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)urea;SE 1702;S 852;N-(4-Methylbenzenesulfonyl)-N′-[3-azabicyclo(3,3,0)oct-3-yl]urea;Diabezidum;Glinormax;Diabrezide;Diaprel;Glyzide;Glimicron;Diabyl;1-(3,3a,4,5,6,6a-Hexahydro-1H-cyclopenta[c]pyrrol-2-yl)-3-(4-methylphenyl)sulfonylurea;1-(4-Methylbenzenesulfonyl)-3-[octahydrocyclopenta[c]pyrrol-2-yl]urea

CAS No.:

21187-98-4

Molecular Formula:

C15H21N3O3S

InChIKeys:

InChIKey=BOVGTQGAOIONJV-UHFFFAOYSA-N

Molecular Weight:

323.41

Exact Mass:

323.41

EC Number:

244-260-5

NSC Number:

758673

DSSTox ID:

DTXSID9023095

ATC Code:

A10BB09|A - Alimentary tract and metabolism

HScode:

29350090

Categories:

Other Chemical Drugs

Characteristics

PSA:

86.9

XLogP3:

2.6

Appearance:

white powder

Density:

1.2205 (rough estimate)

Melting Point:

181 °C

Refractive Index:

1.623

Water Solubility:

methylene chloride: soluble

Storage Conditions:

-20°C Freezer

Toxicity:

LD50 orally in mice: >3 g/kg (Duhault)

Collision Cross Section:

178 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

See More Gliclazide Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Gliclazide Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Semaglutide,Tirzepatide,API,Vitamins,Food Additive

Location:
No. 4C-11-A392, Financial Port, Northwest corner of Fengjing Avenue and Fengxin Road, Fengdong New City, Xi 'an, Shaanxi Province

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
5 days

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2019

Shaanxi TNJONE Pharmaceutical Technology Co., LTD., located in the beautiful ancient capital Xi 'an, is committed to the peptide industry, pharmaceutical raw materials, food and feed additives, veterinary drugs and other fields, the enterprise adhering to provide customers with quality service, supply high-quality products, "world peace and health" as its responsibility, the company adhering to the "meet all customer requirements for products" as the service concept, Guarantee "provide qualified products" as the service principle, so that you get "God-like" noble shopping enjoyment. Our company has more than 1000 kinds of polypeptides, raw materials inventory, at any time to meet the various needs of customers for products. Is your best partner.

Inquiry History

8 Inquiries

Country	Product	Purchase Quantity	Date Posted
Bangladesh	Gliclazide BP	1800 KG	Nov 27, 2023
Bangladesh	Gliclazide BP	1800 KG	Nov 27, 2023
Bangladesh	Gliclazide API BP raw material	2400 KG	Aug 20, 2026
Sri Lanka	Gliclazide BP 2024 / BP 2025	18000 KG	Jun 19, 2026
Indonesia	Gliclazide	1 KG	Jun 9, 2025
Bangladesh	Gliclazide BP	1600 KG	Nov 28, 2023
Bangladesh	Gliclazide	4.00 MT	Dec 11, 2025
Bangladesh	Gliclazide BP	4 MT	Oct 24, 2025

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Anti-Diabetic API 99% Purity Gliclazide Powder CAS 21187-98-4

Product Description

Seller Information

Inquiry History

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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