Supply 99% Sermaglutide Peptide Vials Semaglutide CAS 910463-68-2

  Product Detail 

Name: Semaglutide

CAS#: 910463-68-2

Molecular Formula: C187H291N45O59

Molecular Weight: 4113.57754

Sequence: H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-Cys)-Gly-Ser-Asn-Gly-Pro-Val-Val-Gly-Ala-Pro-Pro-Pro-Ser-NH2

Appearance: White Powder

Purity (HPLC): ≥99.0%

Single Impurity (HPLC): ≤1.0%

Moisture Content (Karl Fischer): ≤10.0%

Peptide Content: ≥80.0%

Storage: Store at -20℃ degrees Celsius in a dry and cool place.

• Certification

  Test Items	Specification	Results
  Appearance	White or almost white loose powder	White loose powder
  Solubility	Freely soluble in water; Firstly, to add freshly boiled and cooled water to make a clear solution containing 0.15mg of semaglutide in lml.Then, to adjust the pHof the solution to 5.5 with 0.05M hydrochloric acid and keep for 30  seconds. Finally, to adjust the pH of the solution to 3.0 and keep 30 seconds. The solution should be turbid in the rang of pH 3.0 to 5.5	Conforms
  Identification By HPLC	The retention time of the principal peak of the test solution corresponds to  that of the reference solution, as obtained in the Assay	Conforms
  Amino acid contect	Asp:0.9-1.1 Ser:2.7-3.3 Glu:4.5-5.5 Gly:3.6-4.4 His: 0.9-1.1 Arg:1.8-2.2 Thr:1.8-2.2 Ala:2.7-3.3 Aib:0.9-1.1 Tyr:0.9-1.1 Val:1.8-2.2 Lys:0.9-1.1 Ile:0.9-1.1 Leu:1.8-2.2 Phe:1.8-2.2 AEEA:Should be detected	0.9 3.0 5.0 4.0 1.1 2.2 2.0 3.0 1.0 1.0 1.9 1.0 0.9 2.0 .9 Conforms
  Molecular lon Mass	4113.58±1.0	Conforms
  pH	7.0-9.0	<8.6
  Water Content(K. F)	NMT 10.0%	4.8%
  Solution clarity and color	Clear and colorless	Conforms
  Related substances (HPLC)	Impurity A: NMT 0.3% Impurity D: NMT 0.3% Any individual impurity: NMT0.1% Total impurities: NMT1.5%	N.D 0.01% Any individual impurity: 0.05%  Total impurities:0.15%
  Sodium ion	1.5%-4.0%	2.8%
  High molecular protein	NMT   0.5%	N.D
  Residual solvent	Methylene chloride NMT 600ppm Acetonitrile NMT 410ppm Methanol NMT 3000ppm DMF  NMT  880ppm Isopropyl ether NMT 5000ppm Isopropanol NMT 5000ppm	N.D 20ppm N.D N.D N.D 65ppm
  Bacterial Endotoxins	NMT   50EU/mg	Conforms
  Microbial Limits	TAMC  NMT  200cfu/g TYMC  NMT  100cfu/g	10cfu/g 20cfu/g
  Acid group ions	Trifluoroacetate ion NMT 0.1% Phosphate ion NMT 0.1% Chloride ion NMT 0.1% Acetate ion NMT 0.1%	N.D N.D N.D N.D
  Polycyclic Aromatic Hydrocarbon	Pass Test	Pass Test
  Assay	95.0%-105.0%(Calculated with reference to the anhydrous and salt-free substance.)	100.6%
  Storage	Preserve in tight containers.Store at a temperature -15℃ to-25℃
  Conclusion:This batch of product complies with Enterprise Standard