Argatroban cas 74863-84-6
74863-84-6
Analytical Reagent
99%
qingdao
AIRUIKE
1kg
Yes
2024-07-17
api,Intermediates,Organic Chemistry,Inorganic Chemistry,Daily Chemicals,Cosmetic Raw Materals
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceWhite to Off-White Crystalline Solid
(2R,4R)-1-[(2S)-5-(diaminomethylideneamino)-2-[(3-methyl-1,2,3,4-tetrahydroquinolin-8-yl)sulfonylamino]-1-oxopentyl]-4-methyl-2-piperidinecarboxylic acid is a peptide.|Argatroban is a direct, selective thrombin inhibitor. The American College of Cardiologists (ACC) recommend using bivalirudin or argatroban in patients who have had, or at risk for, heparin induced thrombocytopenia (HIT) and are undergoing percutaneous coronary intervention. Argatroban is a non-heparin anticoagulant shown to both normalize platelet count in patients with HIT and prevent the formation of thrombi. Parental anticoagulants must be stopped and a baseline activated partial thromboplastin time must be obtained prior to administering argatroban.Basic Info-
Product Name:
Argatroban
Other Name:2-Piperidinecarboxylic acid,1-[(2S)-5-[(aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8-quinolinyl)sulfonyl]amino]pentyl]-4-methyl-,(2R,4R)-;2-Piperidinecarboxylic acid,1-[5-[(aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8-quinolinyl)sulfonyl]amino]pentyl]-4-methyl-,[2R-[1(2S*),2α,4β]]-[partial]-;(2R,4R)-1-[(2S)-5-[(Aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8-quinolinyl)sulfonyl]amino]pentyl]-4-methyl-2-piperidinecarboxylic acid;MD 805;MCI 9038;Argipidine;Argatroban;Novastan;OM 805;GN 1600;Slonnon;DK 7419;MQPA;Acova;Argipidin;Argatra;78238-51-4;169554-65-8;172902-92-0
CAS No.:74863-84-6
Molecular Formula:C23H36N6O5S
InChIKeys:InChIKey=KXNPVXPOPUZYGB-IOVMHBDKSA-N
Molecular Weight:508.63
Exact Mass:508.63
EC Number:1308068-626-2
DSSTox ID:DTXSID7046467
Color/Form:Crystals from ethanol
ATC Code:B - Blood and blood forming organs
HScode:2935009090
Categories:
Characteristics-
PSA:
189
XLogP3:1.3
Appearance:white to off-white crystalline solid
Density:1.47±0.1 g/cm3(Predicted)
Melting Point:188-191 °C
Boiling Point:801.3ºC at 760 mmHg
Flash Point:438.4ºC
Refractive Index:1.674
Water Solubility:In water, 51.35 mg/L at 25 °C (est)
Storage Conditions:Store at +4°C
Vapor Pressure:1.37X10-17 mm Hg at 25 °C (est)
PH:pH 8.8 (Argatroban solution)
Dissociation Constants:pKa1 = 3.06; pKa2 = 11.8 (est)
Experimental Properties:Crystals from aqueous ethanol; MP: 276-280 °C. Specific optical rotation: +76.1 deg at 27 °C/D (c = 1 in 0.2N HCl) /Argatroban monohydrate/
Hazard IdentificationClassification of the substance or mixture
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 3
GHS label elements, including precautionary statements
Pictogram(s) No symbol. Signal word No signal word
Hazard statement(s) H412 Harmful to aquatic life with long lasting effects
Precautionary statement(s) Prevention P273 Avoid release to the environment.
Response none
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
api,Intermediates,Organic Chemistry,Inorganic Chemistry,Daily Chemicals,Cosmetic Raw Materals
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Location:
Huangdao District, Qingdao City, Shandong Province (formerly Room 606-2, Building 1, No. 10 Beijing Road, Jiaonan City)
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Payment Terms:
TT against copy of documents,D/P,D/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
15 days
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
51-100
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Year of Establishment:
2023
Company Certificates-
Credit rating certificate
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Hazardous Chemicals Business License
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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