Didanosine CAS 69655-05-6
69655-05-6
Pharmaceutical Grade
99%
SHANGHAI
airuike
25kg/Cardboard Drum
2025-07-20
api,Intermediates,Organic Chemistry,Inorganic Chemistry,Daily Chemicals,Cosmetic Raw Materals
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceDidanosine(Videx) is a reverse transcriptase inhibitor with an IC50 of 0.49 μM.Target: NRTIs; HIVDidanosine is a dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase. Didanosin
A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase; ddI is then metabolized to dideoxyadenosine triphosphate, its putative active metabolite.
Didanosine is an orally active purine dideoxynucleoside analog indicated for adult and pediatric patients with advanced HIV infection who are either intolerant or significantly deteriorated on zidovudine. It appears to increase CD4 cell counts and decrease p24 antigen levels.Major adverse effects are pancreatitis, peripheral neuropathy and diarrhea.Unlike zidovudine, didanosine exhibits insignificant bone marrow suppression.
White Powder
ChEBI: A purine 2',3'-dideoxyribonucleoside that is inosine in which the hydroxy groups at both the 2' and the 3' positions on the sugar moiety have been replaced by hydrogen.Basic Info-
Product Name:
Dideoxyinosine
Other Name:bmy40900;ddino;nsc612049;2',3'-Dideoxy inosine(DDI);DDI, Didanosine;2.3-Dideoxy;2',3'-Dideoxy-D-inosine;DIDANOSINE / 2'',3''-DIDEOXYINOSINE
CAS No.:69655-05-6
Molecular Formula:C10H12N4O3
InChIKeys:BXZVVICBKDXVGW-NKWVEPMBSA-N
Molecular Weight:236.23
Exact Mass:236.23
BRN:3619529
EC Number:614-994-4
NSC Number:612049
Color/Form:White to Off-white
HScode:29335990
Categories:
Characteristics-
PSA:
88.7
XLogP3:-1.2
Appearance:White to Off-white Powder
Density:1.2917 (rough estimate)
Melting Point:193-195 °C
Boiling Point:193-195 C
Flash Point:275.0±32.9 °C
Refractive Index:-28 ° (C=0.34, H2O)
Water Solubility:1-5 g/100 mL at 21 ºC
Storage Conditions:2-8°C
Vapor Pressure:6.6 mm Hg @ 25 deg C /Estimated/
Specific rotation:D25 -26.3° (c = 10 in water)
PKA:9.12(at 25℃)
Air and Water Reactions:Water soluble.
Critical Temperature & Pressure:Inert atmosphere,Store in freezer, under -20°C
Hazard IdentificationClassification of the substance or mixture
Germ cell mutagenicity, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H341 Suspected of causing genetic defects
Precautionary statement(s) Prevention P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
api,Intermediates,Organic Chemistry,Inorganic Chemistry,Daily Chemicals,Cosmetic Raw Materals
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Location:
Huangdao District, Qingdao City, Shandong Province (formerly Room 606-2, Building 1, No. 10 Beijing Road, Jiaonan City)
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Payment Terms:
TT against copy of documents,D/P,D/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
15
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
51-100
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Year of Establishment:
2023
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Certifications:
Credit rating certificate,Hazardous Chemicals Business License
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