Paracetamol APAP Paracetamol Acetaminphen Acetamiophen Acetaminophen PARACETAMOL BP Paracetamol DC
81 Inquiries
103-90-2
Pharmaceutical Grade
99%
tianjin
longbang
as your requirement
2024-08-03
chemical
-
Product Description
-
Seller Information
-
Inquiry History
-
DescriptionECHEMI Editorial ReferenceAcetaminophen, also known by its common name paracetamol, is a widely utilized medication that serves as an effective analgesic, which means it alleviates pain, and an antipyretic, which refers to its ability to reduce fever. This compound is characterized by its chemical formula C8H9NO2. It is one of the most popular and frequently used over-the-counter drugs available on the market today, and it comes in a variety of formulations to suit different needs and preferences. These formulations can include tablets, capsules, syrups, and even suppositories, making it accessible and convenient for individuals seeking relief from minor aches and pains or the discomfort of fever.
Acetaminophen differs from the nonsteroidal anti-inflammatory agents described in that it is devoid of anti-inflammatory and antirheumatic properties. It was recently shown that acetaminophen, like aspirin, inhibits cyclooxygenase action in the brain and is even stronger than aspirin. On the other hand, the mechanism of analgesic action of acetaminophen is not fully clear, since it acts poorly on peripheral cyclooxygenase.
Acetaminophen is an analgesic and antipyretic compound. Unlike many NSAIDs, which inhibit both COX-1 and COX-2, early studies suggested that acetaminophen is a poor inhibitor of both isoforms. However, it does inhibit COX-2 by 83% and COX-1 by 56% in human bloodex vivo, albeit at a high 1,000 mg dose, with IC50values of 25.8 and 113.7 μM, respectively. Acetaminophen is enzymatically and non-enzymatically converted to several reactive metabolites that contribute to adverse or indirect effects, including liver injury. At toxic doses, the acetaminophen metabolite N-acetyl-4-benzoquinone imine (NAPQI; ) depletes glutathione reserves in the liver, leading to an accumulation of NAPQI and subsequent hepatocyte necrosis. Acetaminophen decreases glutathione levels and reduces glutathione peroxidase activity in mice when administered at a dose of 250 mg/kg and induces ferroptotic cell death in primary mouse hepatocytes, an effect that can be blocked by the ferroptosis inhibitor ferrostatin-1 . Acetaminophen has analgesic and antipyretic properties in animal models.
White Solid
Acetaminophen was first discovered by H. N. Morse in 1878. Although many studies on its use as an analgesic were performed, it wasn’t until 1950 that it was marketed under the name Triagesic. Today, its most common trade names are Tylenol and Panadol, but a large percentage of its sales are as a generic drug. It is the most commonly used medication for pain and fever in both the United States and Europe. It is on the World Health Organization's List of Essential Medicines.Basic Info-
Product Name:
Acetaminophen
Other Name:PARACETAMOL BP2001;PARACETAMOL POWDER BP;PARACETAMOL BP;ACETAMINOPHENOL POWDER PB/USP;PARACETAMOL DC GRADE;PARACETAMOL BP98;PARACETAMOL USP23,BP98;PARACETAMOL POWDER BP2000
CAS No.:103-90-2
Molecular Formula:C8H9NO2
InChIKeys:RZVAJINKPMORJF-UHFFFAOYSA-N
Molecular Weight:151.16
Exact Mass:151.16
BRN:2208089
EC Number:203-157-5
TSCA:TSCA listed
Color/Form:White
HScode:29242930
Categories:
Characteristics-
PSA:
49.33000
XLogP3:1.4236
Appearance:White Solid
Density:1,293 g/cm3
Melting Point:168-172 °C(lit.)
Boiling Point:273.17°C (rough estimate)
Flash Point:188.4±23.2 °C
Refractive Index:1.5810 (rough estimate)
Water Solubility:14 g/L (20 ºC)
Storage Conditions:Acetaminophen preparations should be stored at a temperature less than 40 deg C, preferably between 15-30 deg C; freezing of the oral solution or suspension should be avoided.
Vapor Pressure:0.008Pa at 25℃
Vapor Density:Relative vapour density (air = 1): 5.2
Toxicity:LD50 in mice (mg/kg): 338 orally (Starmer), 500 i.p. (Dahlin, Nelson)
Flammability characteristics:Non flammable
Explosive limit:vol% in air: 15
Odor:odorless
PH:5.5-6.5 (H2O, 20℃)(saturated solution)
PKA:9.86±0.13(Predicted)
Henrys Law Constant:1.5×107mol/(m3Pa) at 25℃, HSDB (2015)
Air and Water Reactions:Slightly soluble in water.
Reactivity Profile:Acetaminophen is sensitive to light. Incompatible with strong oxidizers.
Autoignition Temperature:540 °C
Critical Temperature & Pressure:Inert atmosphere,Room Temperature
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Provision to contain effluent from fire extinguishing. Store in an area without drain or sewer access.Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.
-
-
Seller Information
-
Business Type:
Trader
-
Main Products:
chemical
-
Location:
1803-1, Block A, Huaqiang Plaza, 77 Minzu Road, Xinhua District, Shijiazhuang City, Hebei Province, China
-
Payment Terms:
TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance
-
Average lead Time:
15
-
Total Annual Revenue:
$5 million-$10 million
-
Total Employees:
51-100
-
Year of Establishment:
2023
-
-
Inquiry History81 Inquiries
Country Product Purchase Quantity Date Posted 
Pakistan
Paracetamol 103-90-2
1 MT Oct 5, 2023 
Netherlands
Paracetamol Powder CAS 103-90-2 GMP Factory Supply
1 MT Mar 31, 2026 
Bangladesh
Acetaminophen cas 103-90-2 PARACETAMOL POWDER 99% high quality
70 MT Oct 25, 2023 
Sri Lanka
Hot Sale Pharmaceutical Raw Material CAS 103-90-2 Acetaminophen Powder Paracetamol
88 MT Nov 13, 2023 
Philippines
Paracetamol powder China supplier price 99% White Powder cas 103-90-2 Evergreen EGC-Paracetamol
100 G Nov 9, 2023
Philippines
Paracetamol powder China supplier price 99% White Powder cas 103-90-2 Evergreen EGC-Paracetamol
1 KG Nov 9, 2023 
France
High Purity Acetaminophen Powder Paracetamol at Wholesale Price 99% White Powder 103-90-2 Quanjinci
5 KG Oct 9, 2023 
United Kingdom
acetaminophen
1 KG Jul 10, 2024 
Vietnam
Acetaminophen
1 MT Apr 16, 2025 
India
Paracetamol/Acetaminophen
1.00 KG Sep 27, 2024 
Mexico
Acetaminophen
24 MT Jan 27, 2026
Pakistan
ACETAMINOPHEN
2 KG Aug 25, 2026
United Kingdom
4-Acetamidophenol
100 G Aug 17, 2026
Vietnam
Paracetamol
3 MT Apr 17, 2026
Bangladesh
Paracetamol
10000 KG Feb 25, 2026
India
Paracetamol
1.00 KG Jan 26, 2026 
United States
Acetaminophen
1 KG Dec 15, 2025
India
paracetamol powder ip grade
1.00 KG Dec 12, 2025 
Germany
paracetamol
1 20' Fcl May 27, 2025 
Egypt
N- (4-hydroxyphenyl) Acetamide
2 Mar 10, 2025 Post an enquiry for this product
