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High Quality TNJONE 99% Purity Aminophylline 317-34-0

Name: High Quality TNJONE 99% Purity Aminophylline 317-34-0
Brand: TNJONE
SKU: pr2407091222
Price: 45 USD
Availability: InStock

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Unit Price:

$45-57/KG FOB

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CAS No.:

317-34-0

Grade:

Top Product

Content:

99%

Port:

China Port

Brand:

TNJONE

Packaging:

5g,10g,50g or according to customer's detail requirement.

Price valid (until):

2028-01-31

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Shaanxi TNJONE Pharmaceutical Co., Ltd

Company Type:

Manufactory

Location:

China

Payment Terms:

TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

5 days

Qualification:

Main Products:

Semaglutide,Tirzepatide,API,Vitamins,Food Additive

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Product Details
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Inquiry History

Description

Product Detail

Product Description

What is Aminophylline?

Aminophylline is a compound of the bronchodilator theophylline with in 2:1 ratio.Aminophylline is less potent and
shorter-acting than theophylline. Its most common use is in the treatment of airway obstruction from asthma or COPD

Aminophylline is a drug combination consisting of bronchodilator theophylline and in 2: 1 ratio. It is a kind of non-selective adenosine receptor blocker, histone deacetylase activator and phosphodiesterase inhibition. It is mainly indicated for the treatment of various kinds of lung diseases including asthma, COPD, chronic bronchitis and emphysema. Aminophylline exerts its effect through the component of theophylline in vivo. Theophylline can relax the smooth muscle of the bronchial airways and pulmonary blood vessels. It can competitively inhibits type III and type IV phosphodiesterase (PDE), which breaks down cyclic AMP in smooth muscle cells, possibly leading to bronchodilation. Theophylline also binds to the adenosine A2B receptor to block the adenosine mediated bronchoconstriction. Furthermore, during the inflammatory states, theophylline can activate the histone deacetylase to prevent transcription of inflammatory genes that require the acetylation of histones to initiate the transcription

Product Name:   Aminophylline
Synonyms:   AMinophylline(Phyllocontin, Truphylline);Theophylline-ethylenediaMin e anhydrous COS;(Theophylline)2 Ethylenediamin e, Theophylline hemiethylenediamin e complex, 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione, cmpd. with 1,2-ethanediamine (2:1);Aminophylline,99%;Theophylline-e;Aminophylline hydrat;AMINOPHYLLINE;THEOPHYLLINE COMPOUND WITH ETHYLENEDIAMIN E
CAS:   317-34-0
MF:   C9H16N6O2
MW:   240.27
EINECS:   206-264-5
Product Categories:   Somopphyllin, Aminocadol, Phyllocontin;Miscellaneous Biochemicals;API's;317-34-0
Mol File:   317-34-0.mol

Product Name	Aminophylline
CAS NO	317-34-0
Appearance	Light yellow Powder
Molecular Formula	C16H24N10O4
Molecular Weight	420.43
Category	API
Specification	99%
Storage	Keep in a cool, dry, dark location
Shelf Life	24 months when properly stored

Name	Aminophylline
CAS NO.	317-34-0
purity	99%
Standard packing material	Bag/Box
Appearance	White Powder
Shelf Life	2Years
storage condition and solubility	Inert atmosphere,Store in freezer, under -20°C; soluble in water.

Product COA

Item	Standard	Result
Appearance	White or almost white crystalline powder	Almost white crystalline powder
Melting point	152-156°C	154.6-155.1°C
Specific optical rotation	-16° to -19°	-17.5°
Identification	(1)The retention time of the major peak in the chromatogram of the assay preparation corresponds to that in the chromatogram of the standard preparation,as obtained in the assay.	Complies
	(2)UV absorption Max. at 266nm.	Complies
	(3)IR spectra is consistent with CRS.	Complies
PH	4.5-6.5	5.7
Chloride	0.02% max	<0.02%
Fluorides	4.8%min	4.9%
Related substances	Individual impurity not more than 0.5%	0.35%
Related substances	Total impurities not more than 2.0%	0.76%
Water	0.5% max	0.13%
Residue on ignition	0.1%max	0.06%
Heavy metals	Less than or egual to 20 millionths	Less than20 millionths
Assay(C12H14Cl2FNO4S)	98.0%min	99.0%

Function and Application:

Aminophylline can be used as dicuretic and the medicine helping to relax the smooth muscle .The aminophylline can relax the bronchus and the smooth muscle of the blood vessel,inhibit the kidney tubules to reabsorb the sodium and the water and enhance the extraction of heart oedema and so on .It is usually used as mono-medicine.It is mainly used in medicine field.
Mainly used for asthma, bronchial asthma and chronic bronchitis can also be used for acute heart failure, cardiac asthma, and biliary colic, etc.
Aminophylline is a drug combination consisting of bronchodilator theophylline and ethylenediamin in 2: 1 ratio. It is a kind of non-selective adenosine receptor blocker, histone deacetylase activator and phosphodiesterase inhibition. It is mainly indicated for the treatment of various kinds of lung diseases including asthma, COPD, chronic bronchitis and emphysema. Aminophylline exerts its effect through the component of theophylline in vivo. Theophylline can relax the smooth muscle of the bronchial airways and pulmonary blood vessels. It can competitively inhibits type III and type IV phosphodiesterase (PDE), which breaks down cyclic AMP in smooth muscle cells, possibly leading to bronchodilation. Theophylline also binds to the adenosine A2B receptor to block the adenosine mediated bronchoconstriction. Furthermore, during the inflammatory states, theophylline can activate the histone deacetylase to prevent transcription of inflammatory genes that require the acetylation of histones to initiate the transcription.

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ECHEMI Editorial Reference

Aminophylline is a competitive nonselective phosphodiesterase inhibitor that is used to treat airway obstruction from asthma or COPD.Target: PhosphodiesteraseAminophylline is a compound of the bronchodilator theophylline with ethylenediamine in 2:1 ratio. The ethylenediamine improves solubility, and the aminophylline is usually found as a dihydrate. Aminophylline is less potent and shorter-acting than theophylline. Its most common use is in the treatment of airway obstruction from asthma
Aminophylline is a mixture comprising of theophylline and ethylenediamine in a 2:1 ratio. It has a role as a bronchodilator agent and a cardiotonic drug. It contains a theophylline and an ethylenediamine.|Aminophylline is a drug combination that contains theophylline and ethylenediamine in a 2:1 ratio. Once in the body, theophylline is released and acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. Similar to other theophyllines, aminophylline is indicated for the treatment of lung diseases such as asthma, chronic bronchitis, and COPD. The majority of aminophylline medications are discontinued and the remaining medications on the market are in short supply.|Aminophylline is a methylxanthine and derivative of theophylline. Aminophylline relaxes smooth muscles, particularly bronchial muscles. This xanthine most likely exerts its effect by inhibiting cAMP or cGMP phosphodiesterases, thereby increasing levels of the second messenger cAMP or cGMP intracellularly. Other mode of actions include an adenosine antagonistic effect on the activity of CD4 lymphocytes and mediator release from mast cells thereby decreasing lung sensitivity to allergens and other substances that cause inflammation. Aminophylline also acts as a CNS stimulant and exerts a positive chronotropic and inotropic effect on the heart.|A drug combination that contains THEOPHYLLINE and ethylenediamine. It is more soluble in water than theophylline but has similar pharmacologic actions. It's most common use is in bronchial asthma, but it has been investigated for several other applications.

Certificates

Basic Info

Product Name:

Aminophylline

Other Name:

1H-Purine-2,6-dione,3,9-dihydro-1,3-dimethyl-,compd. with 1,2-ethanediamine (2:1);Theophylline,compd. with ethylenediamine (2:1);1H-Purine-2,6-dione,3,7-dihydro-1,3-dimethyl-,compd. with 1,2-ethanediamine (2:1);Ethylenediamine,compd. with theophylline (1:2);1,2-Ethanediamine,compd. with 3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione (1:2);Aminocardol;Aminophylline;Ammophyllin;Cardophyllin;Carena;Diaphylline;Diophllin;Dobo;Dura-Tab S.M. Aminophylline;Euphyllin;Euphylline;Eurphyllin;Genophyllin;Inophylline;Lasodex;Linampheta;Metaphylline;Methophylline;Neophyiline;Rectalad-aminophylline;Theolamine;Theophyllamine;Aminophyllin;Tefamin;Theophylline compd. with ethylenediamine;Somophyllin O;Metaphyllin;Cardiofilina;Cardophylin;Phylcardin;Cardiomin;Grifomin;Minaphil;Peterphyllin;Stenovasan;Phyllindon;Theophyllaminum;Euufillin;Norofilina;Vasofilina;Diuxanthine;Theolone;Ethophylline;Theophyldine;Miofilin;Carine;Syntophyllin;Aminofilina;Phyllocontin;Cidophylline;Teofyllamin;Novphyllin;Novophyllin;Aminodur;Minaphol;Diophyllin;Euphyllin CR;Somophyllin;Pylcardin;Theomin;Pecram;Theodrox;Euphyllin CR N 300;8013-40-9;12767-26-9;80186-94-3;442519-87-1

CAS No.:

317-34-0

Molecular Formula:

C7H8N4O2.¹/2C2H8N2

InChIKeys:

InChIKey=LHRHXWBJUQKYEL-UHFFFAOYSA-N

Molecular Weight:

420.43

Exact Mass:

420.198212

EC Number:

206-264-5

UNII:

27Y3KJK423

NCI Thesaurus Code:

C47393

Color/Form:

White or slightly yellowish granules or powder

ATC Code:

R - Respiratory system

HScode:

2933990090

Categories:

Other Chemical Drugs

Characteristics

PSA:

191

XLogP3:

-3.03

Appearance:

white to off-white powder

Melting Point:

269-270 °C

Boiling Point:

869.7°C at 760 mmHg

Water Solubility:

H2O: 3.7 mg/mL solutions should be freshly prepared.

Storage Conditions:

−20°C

Toxicity:

LD50 orally in mice: 540 mg/kg (Thompson, Warren)

Odor:

Slight ammoniacal

Taste:

Bitter

Experimental Properties:

Occurs as the dihydrate|Upon exposure to air, gradually loses ethylene diamine and absorbs carbon dioxide with liberation of theophylline

See More Aminophylline Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 3, Oral

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H301 Toxic if swallowed
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product.
Response	P301+P316 IF SWALLOWED: Get emergency medical help immediately. P321 Specific treatment (see ... on this label). P330 Rinse mouth.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20 deg C

See More Aminophylline Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Semaglutide,Tirzepatide,API,Vitamins,Food Additive

Location:
No. 4C-11-A392, Financial Port, Northwest corner of Fengjing Avenue and Fengxin Road, Fengdong New City, Xi 'an, Shaanxi Province

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
5 days

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2019

Shaanxi TNJONE Pharmaceutical Technology Co., LTD., located in the beautiful ancient capital Xi 'an, is committed to the peptide industry, pharmaceutical raw materials, food and feed additives, veterinary drugs and other fields, the enterprise adhering to provide customers with quality service, supply high-quality products, "world peace and health" as its responsibility, the company adhering to the "meet all customer requirements for products" as the service concept, Guarantee "provide qualified products" as the service principle, so that you get "God-like" noble shopping enjoyment. Our company has more than 1000 kinds of polypeptides, raw materials inventory, at any time to meet the various needs of customers for products. Is your best partner.

Inquiry History

1 Inquiries

Country	Product	Purchase Quantity	Date Posted
Pakistan	Aminophylline	42 KG	Sep 10, 2025

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High Quality TNJONE 99% Purity Aminophylline 317-34-0

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