(R)-(-)-Phenylephrine
TDS 2 Inquiries
59-42-7
Pharmaceutical Grade
99%
Shnaghai
Dideu;CT200
1kg/bag
2024-08-09
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial Reference(R)-(-)-Phenylephrine is a selective α1-adrenoceptor agonist primarily used as a decongestant.
Solid
Phenylephrine is a member of the class of the class of phenylethanolamines that is (1R)-2-(methylamino)-1-phenylethan-1-ol carrying an additional hydroxy substituent at position 3 on the phenyl ring. It has a role as an alpha-adrenergic agonist, a cardiotonic drug, a mydriatic agent, a protective agent, a vasoconstrictor agent, a sympathomimetic agent and a nasal decongestant. It is a member of phenylethanolamines, a secondary amino compound and a member of phenols. It is a conjugate base of a phenylephrine(1+).|Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension, dilate the pupil, and induce local vasoconstriction. The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s. Phenylephrine was granted FDA approval in 1939.|Phenylephrine is an alpha-1 Adrenergic Agonist. The mechanism of action of phenylephrine is as an Adrenergic alpha1-Agonist.|Phenylephrine is a direct-acting sympathomimetic amine chemically related to adrenaline and ephedrine with potent vasoconstrictor property. Phenylephrine is a post-synaptic alpha-adrenergic receptor agonist that causes vasoconstriction, increases systolic/diastolic pressures, reflex bradycardia, and stroke output.|An alpha-1 adrenergic agonist used as a mydriatic, nasal decongestant, and cardiotonic agent.Certificates-
TDS
Basic Info-
Product Name:
(-)-Phenylephrine
Other Name:Benzenemethanol,3-hydroxy-α-[(methylamino)methyl]-,(αR)-;Benzyl alcohol,m-hydroxy-α-[(methylamino)methyl]-,(-)-;Benzenemethanol,3-hydroxy-α-[(methylamino)methyl]-,(R)-;(αR)-3-Hydroxy-α-[(methylamino)methyl]benzenemethanol;l-m-Hydroxy-α-[(methylamino)methyl]benzyl alcohol;(-)-m-Hydroxy-α-(methylaminomethyl)benzyl alcohol;Mesaton;Mesatone;Metaoxedrine;Metasympatol;Metasynephrine;m-Methylaminoethanolphenol;Mezaton;(-)-m-Oxedrine;m-Oxedrine;(-)-Phenylephrine;Phenylephrine;m-Sympathol;m-Sympatol;m-Synephrine;Neo-Synephrine;Metaoxedrin;Visadron;(R)-(-)-Phenylephrine;(R)-Phenylephrine;R(-)-Mezaton;l-Phenylephrine;(-)-m-Synephrine;L-Phenylephedrine;(R)-3-[1-Hydroxy-2-(methylamino)ethyl]phenol;Iriphrin;3-[(1R)-1-Hydroxy-2-(methylamino)ethyl]phenol
CAS No.:59-42-7
Molecular Formula:C9H13NO2
InChIKeys:InChIKey=SONNWYBIRXJNDC-VIFPVBQESA-N
Molecular Weight:167.21
Exact Mass:167.21
EC Number:200-424-8
UNII:1WS297W6MV
DSSTox ID:DTXSID9023465
NCI Thesaurus Code:C62067
ATC Code:S01|S01FB01|C - Cardiovascular system|R - Respiratory system|S - Sensory organs
Categories:
Characteristics-
PSA:
52.5
XLogP3:-0.31
Appearance:Solid
Density:1.159 g/cm3
Melting Point:169-172 °C
Boiling Point:341.1ºC at 760 mmHg
Flash Point:163.4ºC
Refractive Index:-55.5 ° (C=5, 1mol/L HCl)
Water Solubility:Freely soluble in water;In water, 1X10+6 mg/L at 25 deg C (est)
Storage Conditions:Store below 40 deg C (104 deg F), preferably between 15 and 30 deg C (59 and 86 deg F), unless otherwise specified by manufacturer. Store in a tight, light-resistant container if not more than 15 mL size. Protect from freezing.
Vapor Pressure:2.2X10-15 mm Hg at 25 deg C (est)
Toxicity:LD50 oral in rat: 350mg/kg
PKA:8.97None
Henrys Law Constant:Henry's Law constant = 6.8X10-15 atm-cu m/mol at 25 °C (est)
Dissociation Constants:8.97|pKa = 8.97
Experimental Properties:CRYSTALS; BITTER; MP: 140-145 °C; FREELY SOL IN WATER OR ALCOHOL; SPECIFIC OPTICAL ROTATION: -46.2 TO -47.2 DEG @ 25 °C/D; AQ SOLN IS NEUTRAL TO LITMUS PAPER /PHENYLEPHRINE HYDROCHLORIDE/|WHITE TO OFF-WHITE, CRYSTALLINE POWDER; PKA: 7.6 /PHENYLEPHRINE HYDROCHLORIDE/|ODORLESS, /PHENYLEPHRINE HYDROCHLORIDE/|Hydroxyl radical reaction rate constant = 1.6X10-10 cu cm/molec-sec at 25 °C (est)
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store below 40 deg C (104 deg F), preferably between 15 and 30 deg C (59 and 86 deg F), unless otherwise specified by manufacturer. Store in a tight, light-resistant container if not more than 15 mL size. Protect from freezing.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst
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Location:
https://www.dideu.com/en/
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
7 days
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Total Annual Revenue:
Above $100 million
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Total Employees:
Above 1000
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Year of Establishment:
2016
Company Certificates-
ISO Certificate
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REACH
">Company Profile -
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Inquiry History2 Inquiries
Country Product Purchase Quantity Date Posted 
India
D- L Phenylephrine Base
25 TON May 17, 2025 
Egypt
Phenylephrine
10 KG Jul 4, 2024 Post an enquiry for this product
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