Veterinary Raw Material CAS266346-15-0 Enrofloxacin Sodium
What is Enrofloxacin Sodium ?
Enrofloxacin (ENR) is a fluoroquinolone antibiotic .
It is a bactericidal agent. The bactericidal activity of enrofloxacin is concentration-dependent, with susceptible bacteria cell death occurring within 20-30 minutes of exposure. Enrofloxacin has demonstrated a significant post-antibiotic effect for both Gram-negative and Gram-positive bacteria and is active in both stationary and growth phases of bacterial replication.
Enrofloxacin is a synthetic antibacterial agent from the class of the fluoroquinolone carboxylic acid derivatives. It has antibacterial activity against a broad spectrum of Gram-negative and Gram-positive bacteria. Its mechanism of action is not thoroughly understood, but it is believed to act by inhibiting bacterial DNA gyrase(a type-II topoisomerase), thereby preventing DNA supercoiling and DNA synthesis.
| Items | Specifications |
| Product name | Enrofloxacin Sodium |
| CAS No. | 266346-15-0 |
| MF | C106H135Cl2N26O31R |
| MW | 2340.2677 |
| EINECS.No | 695-076-0 |
| Melting Point | 238-245 °C (decomp) |
| Appearance | White Powder |
| Shelf Life | 2 Years When Properly Stored |
| Storage | Keep in a cool, dry, dark location in a tightly sealed container or cylinder. |

Specification
| Items | Specifications | Results |
| Character | White or almost white crystalline powder;odorless | white crystelline powder, odorless |
| Melting point | 242~246°C | 243.4~244.3°C |
| Identification | 1) IR spectra is consistent with CRS | complies |
| 2) The retention time of the major peak in the chromatogram of the assay preparation corresponds to that in the chromatogram of the standard preparation, as obtained in the assay | complies |
| Appearance of solution | colorless and clear liquid | colorless and clear liquid |
| Related substances | individual impurity≤1.0% | 0.24% |
| Total impuirties ≤2.0% | 0.70% |
| Loss on ignition | ≤0.5% | 0.32% |
| Residue on ignition | ≤0.1% | 0.05% |
| Heavy metals | Not more than 10 parts per million | Less than 10 parts per million |
| Assay | Not less than 98.0% of C18H14F3N3O6S(On dried basis) | 99.40% |
| Conclusion: | Complies with Ponazuril Enterprise Standard |
Application
1. Dogs and Cats
The product is indicated in the treatment of bacterial infections of the alimentary, respiratory and urogenital tracts, skin, secondary wound infections and otitis externa where clinical experience, supported where possible by sensitivity testing of the causal organism, indicates enrofloxacin as the of choice.
2. Cattle
Diseases of the respiratory and alimentary tract of bacterial or mycoplasmal origin (e.g. pasteurellosis, mycoplasmosis, coli-bacillosis, coli-septicaemia and salmonellosis) and secondary bacterial infections subsequent to viral conditions (e.g. viral pneumonia) where clinical experience, supported where possible by sensitivity testing of the causal organism, indicates enrofloxacin as the of choice.
3. Pigs
Diseases of the respiratory and alimentary tract of bacterial or mycoplasmal origin (e.g. pasteurellosis, actinobacillosis, mycoplasmosis, coli-bacillosis, coli-septicaemia and salmonellosis) and mulifactorial diseases such as atrophic rhinitis and enzootic pneumonia, where clinical experience, supported where possible by sensitivity testing of the causal organism, indicates enrofloxacin as the of choice.
Company Information
Shaanxi TNJONE Pharmaceutical Technology Co., LTD., located in the beautiful ancient capital of Xi 'an, is committed to pharmaceutical raw materials, kill varieties, food and feed additives, chemical reagents, plant extracts and other fields, the enterprise adhering to provide customers with quality service, supply high-quality products. Our company after careful planning, hard study, gradually formed a complete service system, based on the domestic and foreign raw materials market special development. Make the raw materials industry bigger and stronger, and serve the vast number of new and old customers. With "world peace and health" as its responsibility, the company adheres to the service concept of "meeting all requirements of customers for products", and guarantees the service principle of "providing qualified products", so that you can get the "God-like" noble shopping enjoyment. Our company has more than 500 kinds of raw materials inventory at any time to meet the various needs of customers for products. The company's products all comply with the relevant national regulations, from the smallest packaging to tons of goods are available. Is your choice of raw materials the best partner.
Shaanxi TNJONE Pharmaceutical Technology Co., Ltd. is willing to rely on the rapid development of e-commerce and national policy support of the good environment background, nesting, welcome people from all walks of life to visit our company, exchange, and seek common development, looking forward to sharing with you, win-win, to realize the dream.


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