Vitamin B12 Hydroxycobalamin HCl CAS 58288-50-9 Hydroxocobalamin Hydrochloride
What is Hydroxocobalamin Hydrochloride?
Hydroxocobalamin, also known as hydroxycobalamin, is a member of the class of compounds known as cobalamin derivatives. These organic compounds contain a corrin ring, a cobaltatom, and a nucleotide moiety. Cobalamin derivatives are actually derived from vitamin B12. Hydroxocobalamin is practically insoluble (in water) and a moderately acidic compound (based on its pKa). Hydroxocobalamin is formally rated as a possibly carcinogenic (IARC 2B) potentially toxic compound. Hydroxocobalamin is a drug used in the treatment of pernicious anemia and in the prevention and treatment of vitamin B12 deficiency arising from alcoholism, malabsorption, tapeworm infestation, celiac disease, hyperthyroidism, hepatic-biliary tract disease, persistent diarrhea, ileal resection, pancreatic cancer, renal disease, prolonged stress, vegan diets, macrobiotic diets, and other restrictive diets. Hydroxocobalamin is also used in the treatment of known or suspected cyanide poisoning.
| Items | Specifications |
| Product name | Hydroxocobalamin Hydrochloride |
| CAS No. | 58288-50-9 |
| MF | C62H89ClCoN13O15P |
| MW | 1381.83 |
| EINECS.No | 261-200-3 |
| Boiling Point | >300°C (rough estimate) |
| Appearance | Red Powder |
| Shelf Life | 2 Years When Properly Stored |
| Storage | Keep in a cool, dry, dark location in a tightly sealed container or cylinder. |
Certification
| Item | Specification | Test Results | Testing methods |
| Appearance | Dark red, crystals or crystalline powder | Complies | Monograph:0547
Visual method |
| Identifiction A | UV:Absorption maxima at 274±1nm,351±1nm and 525±2nm.274±1nm,351±1nm,525±2nm | Complies | Ph.Eur.monograph Ph.Eur.
<2.2.25> |
A274nm/A351nm: 0.75~0.83
A525nm/A351nm: 0.31~0.35 | 0.79
0.33 |
Identifiction B
| TLC:The principal spot in the
chromatogram obtained with the test
solution is similar in position,colour and
size to the principal spot in the
chromatogram obtained with the
reference solution | Complies
| Ph.Eur.monograph Ph.Eur.
<2.2.27> |
| Identifiction C | Chlorides:It gives reaction(a) of chlorides | Complies | Ph.Eur.monograph<2.3.1>Chlorides |
| Loss on drying | 8.0%~12.0% | 8.4% | Ph.Eur.monograph Ph.Eur<2.2.32> |
| Assay | 96.0%~102.0% | 98.8% | Ph.Eur.monograph Ph.Eur<2.2.25> |
| Related substances | ≤5% | 2% | Ph.Eur.monograph/ Ph.Eur<2.2.29>(HPLC) |
| Acetone | ≤5000ppm | 22ppm | In house/(GC)
(GC)SOP-QC-158-04-03 |
| Total aerobic microbial count | ≤1000cfu/g | <10cfu/g | ChP 2015<1105> |
The total combined
yeasts/mould count | ≤100cfu/g | <10cfu/g |
Applications:
1. Promote the development and maturation of red blood cells, keep the body's hematopoietic function in a normal state, and prevent pernicious anemia;
2. Maintain the health of the nervous system 2. In the form of coenzymes, it can increase the utilization of folic acid and promote the metabolism of carbohydrates, fats and proteins;
3. It has the function of activating amino acids and promotes the biosynthesis of nucleic acids, which can promote the synthesis of proteins, which plays an important role in the growth and development of infants and young children.
4. Metabolize fatty acids so that fats, carbohydrates, and proteins are properly used by the body
5. Eliminate irritability, concentrate, enhance memory and balance
6. It is an indispensable vitamin for the healthy functioning of the nervous system and participates in the formation of a lipoprotein in the nervous tissue.
Company Information
Shaanxi TNJONE Pharmaceutical Technology Co., LTD., located in the beautiful ancient capital of Xi 'an, is committed to pharmaceutical raw materials, kill varieties, food and feed additives, chemical reagents, plant extracts and other fields, the enterprise adhering to provide customers with quality service, supply high-quality products. Our company after careful planning, hard study, gradually formed a complete service system, based on the domestic and foreign raw materials market special development. Make the raw materials industry bigger and stronger, and serve the vast number of new and old customers. With "world peace and health" as its responsibility, the company adheres to the service concept of "meeting all requirements of customers for products", and guarantees the service principle of "providing qualified products", so that you can get the "God-like" noble shopping enjoyment. Our company has more than 500 kinds of raw materials inventory at any time to meet the various needs of customers for products. The company's products all comply with the relevant national regulations, from the smallest packaging to tons of goods are available. Is your choice of raw materials the best partner.
Shaanxi TNJONE Pharmaceutical Technology Co., Ltd. is willing to rely on the rapid development of e-commerce and national policy support of the good environment background, nesting, welcome people from all walks of life to visit our company, exchange, and seek common development, looking forward to sharing with you, win-win, to realize the dream.
FAQ
1.How to get in touch with us?
You can chat with us by Trademanager,WhatsApp or simply giving us an email, a phone call. All our contacts information can be found from our website.
2.Are you a manufacturer or trade company?
We are a professional manufacturer.
3.Can I get a sample?
Yes, free sample can be provided, but shipping cost is covered by your side.
4.What's your MOQ?
It is based on the different product. Some are 1g while some are 1 kg. Please be free to consult our salesman.
5.When can I get the quotation?
We usually quote within 1 hours after we get your inquiry. If it's a urgent order you can call us or mention it in your email subject, and we can take it as priority.
6.Is there any discount?
Yes, some products are applied for discount, but it depends on the quantity.
7.Can you do OEM for me?
Yes,we accept OEM orders, just contact us and give us your requirement. We will offer you a reasonable price and make samples ASAP.
