Dodecylthiocarbonothioylthio)-2-methylpropionic acid N-hydroxysuccinimide ester

Other Name:

2-(Dodecylthiocarbonothioylthio)-2-methylpropionic acid N-hydroxysuccinimide ester

Nature:
-HATU is a solid powder, usually white to pale yellow.
- It is soluble in common organic solvents such as dimethyl sulfoxide and dimethyl formamide at room temperature.
-HATU is an active azo compound that can be used as a carboxyl group activation reagent.

Purpose:
-HATU is mainly used as a carboxyl activating reagent in solid phase synthesis and solution synthesis for the synthesis of peptides and proteins.
Other applications include carboxyl group activation and azo group chemical reactions in organic synthesis.

Preparation:
-HATU is generally formed by the reaction of thiocarbonyl isocyanoyl chloride (CDI) with thiosulfuryl chloride (DCC).

Handling and Storage

Precautions for safe handling

NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Dry. Well closed. Separated from food and feedstuffs and strong oxidants. Store in an area without drain or sewer access.

Inhalation: Remove victim to fresh air and keep at rest in a position comfortable for breathing. Get medical advice/attention if you feel unwell

Skin contact: Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. If skin irritation or rash occurs: Get medical advice/attention.

Eye contact :Rinse cautiously with water for several minutes. Remove contact lenses, if present

Ingestion ： Get medical advice/attention if you feel unwell. Rinse mouth. Protection of first-aiders: A rescuer should wear personal protective equipment, such as rubber gloves and air tight goggles

DISPOSAL CONSIDERATIONS

Recycle to process, if possible. Consult your local regional authorities. You may be able to dissolve or mix material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system. Observe all federal, state and local regulations when disposing of the substance.

REGULATORY INFORMATION

Safe management ordinance of dangerous chemical product (State Council announces on 27/07/2022):

Safe use and production, the storage of a dangerous chemical, transport, loading and unloading were prescribed.

Consignor: Kindchem(Nanjing)Co.,Ltd

Add:No.8-4,HongGuang Road Qinhuai District,Nanjing City,China,210006

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