Low Price Alpha-Tocopheryl Succinate CAS 4345-03-3 Vitamin E Acid Succinate
TDS 3 Inquiries
4345-03-3
Food Grade
98%
china any port
TNJONE
1kg ,25kg or according to customer's detail requirement.
2028-01-31
Semaglutide,Tirzepatide,API,Vitamins,Food Additive
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceOff-White to Pale Yellow Solid
D-alpha-tocopheryl acid succinate is a white powder. (NTP, 1992)
D-alpha-tocopheryl acid succinate is a white powder. (NTP, 1992)|Tocopherol succinate is a tocol and a hemisuccinate.|Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the alpha-tocopherol stereoisomers. Moreover, manufacturers typically convert the phenol component of the vitamin to esters using acetic or succinic acid, making a compound such as alpha-tocopherol succinate more stable and easier to use in vitamin supplements. Alpha-tocopherol succinate is subsequently most commonly indicated for dietary supplementation in individuals who may demonstrate a genuine deficiency in vitamin E. Vitamin E itself is naturally found in various foods, added to others, or used in commercially available products as a dietary supplement. The recommended dietary allowances (RDAs) for vitamin E alpha-tocopherol are: males = 4 mg (6 IU) females = 4 mg (6 IU) in ages 0-6 months, males = 5 mg (7.5 IU) females = 5 mg (7.5 IU) in ages 7-12 months, males = 6 mg (9 IU) females = 6 mg (9 IU) in ages 1-3 years, males = 7 mg (10.4 IU) females = 7 mg (10.4 IU) in ages 4-8 years, males = 11 mg (16.4 IU) females = 11 mg (16.4 IU) in ages 9-13 years, males = 15 mg (22.4 IU) females = 15 mg (22.4 IU) pregnancy = 15 mg (22.4 IU) lactation = 19 mg (28.4 IU) in ages 14+ years. Most individuals obtain adequate vitamin E intake from their diets; genuine vitamin E deficiency is considered to be rare. Nevertheless, vitamin E is known to be a fat-soluble antioxidant that has the capability to neutralize endogenous free radicals. This biologic action of vitamin E consequently continues to generate ongoing interest and study in whether or not its antioxidant abilities may be used to help assist in preventing or treating a number of different conditions like cardiovascular disease, ocular conditions, diabetes, cancer and more. At the moment, however, there exists a lack of formal data and evidence to support any such additional indications for vitamin E use. Moreover, although it is generally believed that alpha-tocopherol succinate would naturally demonstrate such general vitamin E-tocopherol pharmacodynamics after undergoing a logical de-esterification in the gut, there is ongoing research that proposes that the alpha-tocopherol succinate compound itself is capable of eliciting anti-cancer and inflammation mediation activities that are unique from the alpha-tocopherol form and other alpha-tocopherol esters.|A natural tocopherol and one of the most potent antioxidant tocopherols. It exhibits antioxidant activity by virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus. It has four methyl groups on the 6-chromanol nucleus. The natural d form of alpha-tocopherol is more active than its synthetic dl-alpha-tocopherol racemic mixture.
Tocopherol succinate (4345-03-3) is a potent antioxidant. Protects mice from gamma-radiation by induction of granulocyte-colony stimulating factor.1,2Tocopherol succinate induces apoptosis in human gastric cancer cells3and inhibits proliferation of mesothelioma cells by down-regulation of fibroblast growth factor receptor-14. Induces apoptosis in neuroblastoma cells.5
ChEBI: Tocopherol succinate is a tocol and a hemisuccinate.CertificatesBasic Info-
Product Name:
D-α-Tocopherol succinate
Other Name:1210IU D-α-Tocopherol succinate,vitamin E succinate 1185IU D-α-Tocopherol succinate,vitamin E succinate;(+)-α-TOCOPHEROL ACID SUCCINATE;D-α-Tocopheryl succinate, Ph. Eur.;[2theta-[2theta(4theta,8theta)]]-cyl)-2h-1-benzopyran-6-yl]este;alpha-tocopherol,succinate;alpha-tocopherolhemisuccinate;butanedioicacid,mono(3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltride;butanedioicacid,mono[3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltride
CAS No.:4345-03-3
Molecular Formula:C33H54O5
InChIKeys:IELOKBJPULMYRW-NJQVLOCASA-N
Molecular Weight:530.78
Exact Mass:530.78
BRN:4038233
EC Number:224-403-8
UNII:LU4B53JYVE
TSCA:TSCA listed
DSSTox ID:DTXSID2026151
Color/Form:White or off-white
HScode:2936280000
Categories:
Characteristics-
λmax:
286nm(EtOH)(lit.)
PSA:72.8
XLogP3:11.88
Appearance:D-alpha-tocopheryl acid succinate is a white powder. (NTP, 1992)
Density:1.002±0.06 g/cm3(Predicted)
Melting Point:~76 °C(lit.)
Boiling Point:625.8±55.0 °C(Predicted)
Flash Point:187.0±25.0 °C
Refractive Index:1.498
Water Solubility:H2O: less than 0.1 mg/mL at 64° F (NTP, 1992)
Storage Conditions:2-8°C
Vapor Pressure:0Pa at 20℃
Toxicity:LD50 oral in rat: > 7gm/kg
Flammability characteristics:Not classified
Odor:Little or no odor
PKA:4.35±0.17(Predicted)
Air and Water Reactions:Insoluble in water.
Reactive Group:Acids, Carboxylic
Reactivity Profile:Vitamin E succinate is an ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.
Critical Temperature & Pressure:-20°C
Hazard IdentificationClassification of the substance or mixture
Not classified.
GHS label elements, including precautionary statements
Pictogram(s) No symbol. Signal word No signal word
Hazard statement(s) none
Precautionary statement(s) Prevention none
Response none
Storage none
Disposal none
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Semaglutide,Tirzepatide,API,Vitamins,Food Additive
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Location:
No. 4C-11-A392, Financial Port, Northwest corner of Fengjing Avenue and Fengxin Road, Fengdong New City, Xi 'an, Shaanxi Province
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
5
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
11-50
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Year of Establishment:
2019
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Inquiry History3 Inquiries
Country Product Purchase Quantity Date Posted 
India
TOCOPHEROL SUCCINATE
35 KG Jul 16, 2025 
Brazil
Vitamin E Succinate
100 KG Aug 28, 2023 
United States
D-Alpha Tocopheryl Acid Succinate CAS 4345-03-3 D-Alpha-Tocopherol Succinate/Vitamin E Succinate
50 KG Nov 22, 2025 Post an enquiry for this product
