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Online Hot Sale High Quality Metronidazole/Methyl-5-Nitroimidazole-1-Ethanol/Antiparasitics/CAS No. 443-48-1/Yellowish Crystalline Powder

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CAS No.:

443-48-1

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Qingdao

Brand:

TNN

Packaging:

25kg drum

Sample Available:

Yes

Price valid (until):

2025-12-31

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The TNN Development Limited

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents,D/P,L/C,D/A,O/A

Average Lead Time:

30 days

Qualification:

Main Products:

Sodium benzoate,Potassium sorbate,Xanthan gum,phosphoric acid,citric acid,Aminophylline anhydrous

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Product Description
Seller Information
Inquiry History

Description

Product Detail

Metronidazole is a antibiotic and antiprotozoal medication. It is used either alone or with other antibiotics to treat pelvic inflammatory disease, endocarditis, and bacterial vaginosis among others.

It is effective for dracunculiasis, giardiasis, trichomoniasis, and amebiasis. It is the drug of choice for a first episodes of mild-to-moderate clostridium difficile colitis. Metronidazole is available by mouth, as a cream, and intravenously.

Drugs of choice for the treatment of bacterial vaginosis include metronidazole and clindamycin. The treatment of choice for bacterial vaginosis in nonpregnant women include metronidazole oral twice daily for seven days, or metronidazole gel intravaginally once daily for five days, or clindamycin intravaginally at bedtime for seven days. For pregnant women, the treatment of choice is metronidazole oral three times a day for seven days.

Product Name:Metronidazole
CAS:443-48-1
MF:C6H9N3O3
MW:171.15
Melting Point:159-161 °c (Lit.)
Boiling Point:301.12°c (Rough Estimate)
Density:1.3994 (Rough Estimate)
PKA: 2.62(H2O, T =25±0.2, (undefined)
Solubility:Acetic Acid: 0.1m, Clear, Faintly Yellow
Factory stock Metronidazole Antibacterials Raw Material with competitive price

Test items	Specifications	Results
Appearance	White or yellowish,crystalline powder	Yellowish crystalline powder
Solubility	Slightly soluble in water, in acetone, in alcohol and in methylene, chloride	COMPLY
Identification	First Identification:C Second Identification:A,B,D
a) Melting point	a) Between 159ºC to 163ºC	a) 161.1ºC to 161.6ºC
b) UV	b) The specific absorbance at the maximum is 365 to 395.	b) 380
c) IR	c) Comparison Metronidazole CRS.	c) COMPLY
d) Chemical	d) The solution gives the reaction of primary aromatic amines.	d) COMPLY
Appearance of solution	SUSPENSION II AND SOLUTION GY6	COMPLY
Related Substances Any individual impurity Total impurities	0.1% MAX 0.2% MAX	0.006% 0.01%
Heavy Metals	20PPM MAX	<20PPM
Loss on drying	0.5% MAX	0.12%
Sulphated ash	0.1% MAX	0.04%
Organic residues	1ppm MAX	N.D
Assay	99.0% - 101.0% C₆H₉N₃O₃(On dried basis)	99.9% C₆H₉N₃O₃
Conclusion :	This product complies with the standard of BP2020.
We hereby certify that the above is true and correct.

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Metronidazole is a nitroimidazoleantibiotic medication used particularly for anaerobicbacteria and protozoa.
Metronidazole is an antibiotic, amebicide, and antiprotozoal.
Metronidazole is the drug of choice for first episodes of mild-to-moderate Clostridium
difficile infection.
Metronidazole has obvious effect for amebiasis
Shop High Purity Metronidazole Powder CAS 443-48-1 with Best Price-Detailed Image 2 Metronidazole is a antibiotic and antiprotozoal medication. It is used either alone or with other antibiotics to treat pelvic inflammatory disease, endocarditis, and bacterial vaginosis among others.

It is effective for dracunculiasis, giardiasis, trichomoniasis, and amebiasis. It is the drug of choice for a first episodes of mild-to-moderate clostridium difficile colitis. Metronidazole is available by mouth, as a cream, and intravenously.

Drugs of choice for the treatment of bacterial vaginosis include metronidazole and clindamycin. The treatment of choice for bacterial vaginosis in nonpregnant women include metronidazole oral twice daily for seven days, or metronidazole gel intravaginally once daily for five days, or clindamycin intravaginally at bedtime for seven days. For pregnant women, the treatment of choice is metronidazole oral three times a day for seven days.

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Our Advantages:
Who are we?
1. TNN was founded in 1998 with headquarters in Dalian, branch offices in USA, Austrilia.
2. ISO9001 Certificated,annual Sales Amount 28million US dollors, cooperative ralationship with 60+countries.

What we can do?
1. Customer-oriented sourcing and supply service.
2. Pre-shipment sample test and third-party inspection to assure product quality.
3. Customized label and packing, reinforced palletizing method to keep cargo in good condition.
4. Professtional service on mixed container load with 20+ different products in one consignment.
5. Fast speed of delivery under multiple modes of trasportation including sea,railway,air,courier.

Advantages:
1.     25-year export experience
2.     Mix container and professional loading with taking photos of every step.
3.     Our own lab, test pre-shipment sample before shipment and keep batch samples

Strict quality control:
Firstly test pre-shipment sample by TNN's lab,
If test succeeds, deliver (same batch) pre-shipment sample and confirm the Original COA with clients,
After confirmation we ship the (same batch) cargos.
If test fails,shipment suspends,TNN corrects and offers qualified one.

Mission interpretation

Income: Stable and keep rising

Well-off life: Have a car and there own house, Children can get a good education，The old can be supported

Work hard: become an expert in our field

The fastest delivery, The fastest shipment , The fastest documents

Transportation for mixed products containers and dangerous cargos

Keep stock

Provide market analysis report

Multiple payment ways long payment periods

Exported dihydroartemisinin to Nigeria to make the medicine for malari。

The Charity Federation of Africa raised money and bought a water line

give discounts , timely delivery with insufficient balance.

In 2006,TNN passed verification of ISO 9001:2008.Since 2016,TNNhas established 3 overseas companies and warehouses in USA,AUS,UAE to keep fast delivery.Meanwhile TNN now is shareholder offactories for some food additives,mini air pump and easy pull cap.

The TNN Development Limited is a manufacturing and distributinggroup for food additives and machine with ISO 9001:2008 Certificate.TNN is working closely with partners from Europe,Asia,North America,Latin America and Africa for export business of below:

●Food Additives & Plant Extracts

●Fine Chemicals

●Cosmetics

●Pharmaceutical Raw Materials(API)

ECHEMI Editorial Reference

Metronidazole is a nitroimidazole antibiotic first isolated in the 1950s. Many nitroimidazoles were being studied at the time, as the class was found to have trichomonacidal properties. Metronidazole was of particular interest due to its high activity against Trichomonas vaginalis and Entamoeba histolytica both in vitro and in vivo as well as clinical activity against many anaerobic pathogens including Gram-positive and Gramnegative bacteria and Giardia lamblia. Metronidazole is often used clinically for intra-abdominal infections and is the firstline treatment for Clostridium difficile–associated diarrhea.
Metronidazole is an odorless, white, yellow, or cream-colored crystalline solid. Darkens on exposure to light. Bitter, salty taste (do not test). Soluble in hot water, slightly soluble in ethanol, slightly soluble in water or chloroform, very slightly soluble in ether.
ChEBI: Metronidazole is a member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death. It has a role as an antitrichomonal drug, a prodrug, an antibacterial drug, an antimicrobial agent, an antiparasitic agent, a xenobiotic, an environmental contaminant, a radiosensitizing agent and an antiamoebic agent. It is a member of imidazoles, a C-nitro compound and a primary alcohol. It is a conjugate base of a metronidazole(1+).
White to pale-yellow crystalline powder with a slight odor. Bitter and saline taste. pH (saturated aqueous solution) about 6.5.
Confirmed carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic, and teratogenic data. Moderately toxic by ingestion, intraperitoneal, and subcutaneous routes. Human systemic effects by ingestion: paresthesia, nerve or sheath structural changes, eye changes, tremors, fever, jaundice and other liver changes, hearingacuity changes, somnolence, and ataxia. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

Certificates

Basic Info

Product Name:

Metronidazole

Other Name:

TIMTEC-BB SBB001486;1-(2-hydroxyethyl)-2-methyl-5-nitroimidazole;1-(beta-Hydroxyethyl)-2-methyl-5-nitroimidazole;1-(beta-Oxyethyl)-2-methyl-5-nitroimidazole;1H-Imidazole-1-ethanol, 2-methyl-5-nitro-;1H-Imidazole-1-ethanol,2-methyl-5-nitro-;1-Hydroxyethyl-2-methyl-5-nitroimidazole;2-Methyl-1-(2-hydroxyethyl)-5-nitroimidazole

CAS No.:

443-48-1

Molecular Formula:

C6H9N3O3

InChIKeys:

VAOCPAMSLUNLGC-UHFFFAOYSA-N

Molecular Weight:

171.15

BRN:

611683

EC Number:

207-136-1

Color/Form:

white to light yellow

HScode:

29332990

Categories:

Bulk Drug Intermediates

Characteristics

Density:

1.3994 (rough estimate)

Melting Point:

159-161 °C (lit.)

Boiling Point:

301.12°C (rough estimate)

Refractive Index:

1.5800 (estimate)

Water Solubility:

<0.1 g/100 mL at 20 ºC

Toxicity:

Metronidazole is a prodrug that requires reductive activation of the nitro group by susceptible organisms. The reduction causes nitro radical formation and destruction of the organism’s DNA. The mechanism of neurotoxicity is thought to be due to axonal degeneration. Metronidazole has been shown to bind neuronal RNA in rodent models, thus inhibiting protein synthesis and causing degeneration. Metronidazole is also capable of producing a disulfiram-type reaction with ethanol ingestion. This reaction is hypothesized to occur due to metronidazole inhibition of aldehyde dehydrogenase.

PKA:

pKa 2.62(H2O,t =25±0.2,Iundefined) (Uncertain)

Henrys Law Constant:

5.8×105mol/(m3Pa) at 25℃, HSDB (2015)

Air and Water Reactions:

Insoluble in water.

Reactivity Profile:

Metronidazole darkens on exposure to light. Metronidazole is incompatible with strong oxidizing agents. .

Critical Temperature & Pressure:

2-8°C

See More Metronidazole Properties 

Hazard Identification

Classification of the substance or mixture

Germ cell mutagenicity, Category 2

Carcinogenicity, Category 1B

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 3

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H341 Suspected of causing genetic defects H350 May cause cancer H412 Harmful to aquatic life with long lasting effects
Prevention	P203 Obtain, read and follow all safety instructions before use. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P273 Avoid release to the environment.
Response	P318 IF exposed or concerned, get medical advice.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

PRECAUTIONS FOR "CARCINOGENS": Storage site should be as close as practical to lab in which carcinogens are to be used, so that only small quantities required for ... expt need to be carried. Carcinogens should be kept in only one section of cupboard, an explosion-proof refrigerator or freezer (depending on chemicophysical properties ...) that bears appropriate label. An inventory ... should be kept, showing quantity of carcinogen & date it was acquired ... Facilities for dispensing ... should be contiguous to storage area. Chemical Carcinogens

See More Metronidazole Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Sodium benzoate,Potassium sorbate,Xanthan gum,phosphoric acid,citric acid,Aminophylline anhydrous

Location:
RM2901, Rainbow Building, No.23, Renmin Road, Zhongshan Dist.

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A

Average lead Time:
30 days

Total Annual Revenue:
$10 million-$25 million

Total Employees:
11-50

Year of Establishment:
2006

Company Certificates
- QUALITY MANAGEMENT SYSTEM CERTIFICATE
- kosher certification
- SERTIFIKAT HALAL-HALAL CERTIFICATE
- EU GMP
Over 25 Years' Import and Export Experience
TNN was founded in 1998 in Dalian China with headquarter in Dalian, overseas branch offices in the USA, Australia, and Dubai. TNN has three domestic branches in Jilin, Shanghai, and Shenyang. Mix container and professional loading with taking photos of every step. Our own laboratory, pre-shipment sample before shipment, and keep batch samples.

Our Products
Specialize in chemicals, fashion accessories, lotion pumps & sprayers, tyres, gloves & other epidemic prevention products, and bottle caps supplying to all over the world. TNN will make your life better.

ISO9001:2015 Company with Perfect Loading
Certified by ISO9001, CE, GMP, FDA, specializing in food, feed additives, APIS, Cosmetics, Medical instruments, chemical raw materials, and more.

Exporting to 60+ Countries
Our products have been sold to clients all over the world, such as Japan, Korea, Mideast, Middle Asia, Europe, Africa, India, South America, keeping a cooperative relationship with 60+ countries. We are firmly committed to our mission of creating a global trade network on supply, sales, and service.

Cooperate with Us Today
Contact us today to discuss mutually beneficial cooperation.

Inquiry History

15 Inquiries

Country	Product	Purchase Quantity	Date Posted
Bangladesh	METRONIDAZOLE	20000 KG	Aug 7, 2026
Pakistan	METRONIDAZOLE	500 KG	Jun 12, 2026
Philippines	Metronidazole	150 G	Jan 20, 2026
India	Metronidazole	2000 KG	Jan 4, 2026
Saudi Arabia	Metronidazole Powder	1 KG	Sep 18, 2025
Uzbekistan	Metronidazole	10000 KG	Sep 10, 2026
Yemen	Metronidazole	10 G	Jan 15, 2026
Pakistan	METRONIDAZOLE PLAIN	1000 KG	Apr 14, 2025
Pakistan	METRONIDAZOLE	1500 KG	May 7, 2024
Turkey	METRONIDAZOLE BASE	100 KG	Apr 2, 2024
Philippines	metronidzole	1 G	Oct 19, 2023
Pakistan	Metronidazole	1 KG	Aug 20, 2026
India	Metronidazole BP	10.00 MT	Apr 16, 2026
Pakistan	Metronidazole	100.00 KG	Dec 31, 2024
India	METRONIDAZOLE PLAIN IP	1000.00 KG	Mar 13, 2024

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Online Hot Sale High Quality Metronidazole/Methyl-5-Nitroimidazole-1-Ethanol/Antiparasitics/CAS No. 443-48-1/Yellowish Crystalline Powder

Product Description

Seller Information

Inquiry History

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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