Supply Favorable Price Chemical Powder Safinamide, CAS no 133865-89-1
133865-89-1
Pesticide Grade
99%
QINGDAO
QSC=Qingdao Baishiwei Chemical
25kg drum
Yes
2025-01-24
ghk cu
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceSafinamide (EMD 1195686; FCE 26743) selectively and reversibly inhibits MAO-B with IC50 of 98 nM, exhibits 5918-fold selectivity against MAO-A.IC50 value: 98 nM [1]Target: MAO-BSafinamide (EMD 1195686; FCE 26743; ) is a highly selective and reversible monoamine oxidase type B (MAO-B) inhibitor that increases neostriatal dopamine concentration. In addition, Safinamide (EMD 1195686; FCE 26743; ) is voltage-dependent sodium and calcium channel blocker. Safinamide (EMD 1195686; FCE 26743; )
Safinamide is an amino acid amide.|Safinamide is for the treatment of parkinson's disease. It was approved in Europe in February 2015, and in the United States on March 21, 2017.|Safinamide is a Monoamine Oxidase Type B Inhibitor. The mechanism of action of safinamide is as a Monoamine Oxidase-B Inhibitor, and Breast Cancer Resistance Protein Inhibitor.|Safinamide is an inhibitor of monoamine oxidase used as adjunctive therapy in combination with levodopa and carbidopa in the management of Parkinson’s disease. Safinamide has been associated with a low rate of serum enzyme elevations during treatment, but has not been linked to instances of clinically apparent acute liver injury.Basic Info-
Product Name:
Safinamide
Other Name:Propanamide,2-[[[4-[(3-fluorophenyl)methoxy]phenyl]methyl]amino]-,(2S)-;Propanamide,2-[[[4-[(3-fluorophenyl)methoxy]phenyl]methyl]amino]-,(S)-;(2S)-2-[[[4-[(3-Fluorophenyl)methoxy]phenyl]methyl]amino]propanamide;FCE 26743;Safinamide;(S)-2-[[4-[(3-Fluorobenzyl)oxy]benzyl]amino]propanamide;EMD 1195686;(2S)-2-[[4-[(3-Fluorophenyl)methoxy]phenyl]methylamino]propanamide;(S)-2-[[[4-[(3-Fluorophenyl)methoxy]phenyl]methyl]amino]propanamide
CAS No.:133865-89-1
Molecular Formula:C17H19FN2O2
InChIKeys:InChIKey=NEMGRZFTLSKBAP-LBPRGKRZSA-N
Molecular Weight:302.347
Exact Mass:302.34
EC Number:603-772-2
UNII:90ENL74SIG
ATC Code:N04B|N04BD03|N - Nervous system
Categories:
Characteristics-
PSA:
64.4
XLogP3:2.2
Density:1.189±0.06 g/cm3(Predicted)
Melting Point:208-212°
Boiling Point:476.7±40.0 °C(Predicted)
Flash Point:242.1±27.3 °C
Refractive Index:1.570
Vapor Pressure:2.98E-09mmHg at 25°C
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
Eye irritation, Category 2
Reproductive toxicity, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
H319 Causes serious eye irritation
H361 Suspected of damaging fertility or the unborn child
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P203 Obtain, read and follow all safety instructions before use.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
ghk cu
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Location:
No. 33688 Jingshi East Road, High-tech Zone, Jinan City, Shandong Province, Jinan Comprehensive Bonded Zone Customs supervision warehouse supporting office area 101-B3
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Payment Terms:
100% TT in advance
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Average lead Time:
120 days
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Total Annual Revenue:
$1 million-$2.5 million
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Total Employees:
11-50
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Year of Establishment:
2021
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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