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Home > Pharmaceutical Intermediates > Analgesics > Indomethacin for Sale > USP / ISO Raw Material Anti-Inflammatory Powder CAS 53-86-1 Indometacin
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USP / ISO Raw Material Anti-Inflammatory Powder CAS 53-86-1 Indometacin

11 Inquiries

Unit Price: Get Latest Price
CAS No.:

53-86-1

Grade:

Pharmaceutical Grade

Content:

99%

Port:

TianJing

Brand:

HebeiShunXing

Packaging:

25KG/Bag

Price valid (until):

2025-08-08

Company Type:
Trader
Location:
China
Qualification:
Main Products:

HPMC,Lithium Carbonate,Cellulose Acetate Tow,EVA resin,Terpene Resin,PP fiber

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Product name:Indometacin Powder
    Other Name:Indomethacin
    Appearance:White  Powder
    CAS:53-86-1
    M.F:C19H16ClNO4
    M W:357.79
    Grade:Pharmaceutical Grade
    Specification:99%



    Indomethacin is a kind of stronger corticoid anti-inflammatory and antipyretic and analgesic, by inhibiting cyclooxygenase reducing the synthesis of prostaglandin (PG), to prevent the formation of the nere impulses, inflammation tissue inhibiting inflammatory reaction, including inhibition of leukocyte chemotaxis and lysosomal enzyme release, etc., and produce antipyretic, analgesic and anti-inflammatory effects.Indomethacin anti-inflammatory, antipyretic effect is very strong, its anti-inflammatory effect is better than bute, 84 times better than hydocortisone, and sugar cortical hormone, used in combination with aspirin, bute, can reduce their dosage, toxic and side effects, improve curative effect; Second is antipyretic effect, 10 times than amidopyrine ;its analgesic action is weak , only to the inflammatory pain has obvious analgesic effect, but the effect is good for inflammatory pain than Baotai loose, analgin and salicylic acid. 






    Packing and transportation  


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    The product is packed in polyethylene bag enclosed in composite fiberboard drum or paper bag.
    The net weight is 25 kg/drum or 25 kg/bag  .
    The product should be kept in the original bag and stored in the dry and clean place far away from the source of heat and not put together with other chemicals.


      Corporate advantage


    Hebei Shunxing Import and Export Co., Ltd.is a large chemical trading company in North China. The company not only excels in service, but also strictly controls product quality.

    Over the years, quality testing technology has been continuously improved, and an industry level quality inspection and supervision system has been established. Equipped with advanced domestic quality testing instruments, product quality has steadily improved, winning the support and trust of more customers!

    The company has established a sound and excellent domestic and international marketing system, providing customers with various high-quality and cost-effective chemical raw materials.

    At the same time, it fully utilizes its extensive sales channels and business experience, and also leverages the advanced professional technology of foreign partners such as Japan to provide customers with consulting services such as technology introduction. As a professional trading company, we have maintained good cooperative relationships with major manufacturers across the country for a long time, and have signed long-term sales agency contracts with multiple domestic and foreign customers.

    We have a stable and good customer base in both domestic and foreign markets, and have also established reliable partnerships with well-known enterprises in countries and regions such as Japan and Southeast Asia.


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    P roduction:our associate factory possesses 20000T/a of capacity for Phospha tes & 3000T/a of capacity for polymers. And it possess production facility conforms to G M P standard, which could assure you high quality APIs and intermediates.

    R & D: our associate factory own synthetic and biochemical labs, sophisticated multifunctional pilot workshop which is able to customize chemical products from the level in gram to that in kilogram and excel at process scale-up from lab to workshop.

    Export:1. Water treatment chemicals, mainly includes series of organic , biocide and polymer.
    2. Fine chemicals, mainly includes flame retardant, pharmaceutical raw materials & intermediates. Our products are exported to many countries and areas such as Europe, North America, South America, Southeast Asia, etc.


    Basic Info
    Product Name:

    Indomethacin

    Other Name:

    1H-Indole-3-acetic acid,1-(4-chlorobenzoyl)-5-methoxy-2-methyl-;Indole-3-acetic acid,1-(p-chlorobenzoyl)-5-methoxy-2-methyl-;1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid;Amuno;1-(p-Chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid;1-(p-Chlorobenzoyl)-2-methyl-5-methoxyindole-3-acetic acid;α-[1-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indolyl]acetic acid;Indocid;Indocin;Indometacin;Indomethacin;Indomethacine;Metindol;N-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indolylacetic acid;1-(p-Chlorobenzoyl)-5-methoxy-2-methyl-3-indolylacetic acid;Artrinovo;Artrivia;Confortid;Idomethine;Inacid;Indomed;Indomee;Infrocin;Mezolin;Methazine;Indacin;1-(4-Chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid;Indomecol;Metacen;Metartril;Dolovin;Indo-Rectolmin;Reumacide;Sadoreum;1-(4-Chlorobenzoyl)-2-methyl-5-methoxyindole-3-acetic acid;Indometacine;1-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indolylacetic acid;Indren;Inteban;Chrono-Indocid 75;Dolcidium PL;Bonidon Gel;Imbrilon;Indomod;Indo-Phlogont;Indo-Tablinen;Dolcidium;Bonidin;Mobilan;Indomethine;Inflazon;Elmetacin;Indoxen;Vonum;Tannex;Durametacin;Indoptic;Argun;Mikametan;Catlep;Indoptol;Chrono-Indicid;Lausit;Rheumacin LA;Inteban SP;Chibro-Amuno;Artracin;Indorektal;Indocid (pharmaceutical);Innamit;Indonol;[1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid;Vital Vitacid;IndoRich;Flam;Globa;NSC 77541;Indocollyre;Endol;37242-43-6;91853-74-6;503560-73-4

    CAS No.:

    53-86-1

    Molecular Formula:

    C19H16ClNO4

    InChIKeys:

    InChIKey=CGIGDMFJXJATDK-UHFFFAOYSA-N

    Molecular Weight:

    357.79

    Exact Mass:

    357.79

    EC Number:

    200-186-5

    HScode:

    29339900

    Categories:

    Analgesics

    Characteristics
    PSA:

    68.5

    XLogP3:

    3.4

    Appearance:

    Crystals. (NTP, 1992)

    Density:

    1.38 g/cm3

    Melting Point:

    158 °C

    Boiling Point:

    499.4ºC at 760 mmHg

    Flash Point:

    255.8ºC

    Water Solubility:

    soluble in acetone (40 mg/mL - clear, yellow solution), ethanol (20 mg/mL), ether, castor oil; soluble in chloroform (50 mg/mL - clear, yellow, extremely viscous solution); decomposed by strong alkali but stable in neutral or slightly acidic media; insoluble in water.ethanol: 50 mg/mL, clear, yellow-green

    Storage Conditions:

    Store at RT

    Vapor Pressure:

    9.89X10-11 mm Hg at 25 deg C (est)

    Toxicity:

    Oral-Rat  LD50 2.42  mg/kg; Oral-Mouse LD50: 11.84 mg/kg

    Flammability characteristics:

    Open flame is flammable; high heat decomposes toxic chloride and nitrogen oxide gas

    Odor:

    Odorless, or has slight odor

    Taste:

    Slight, bitter

    PKA:

    4.5None

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 2, Oral

    Skin sensitization, Category 1

    Reproductive toxicity, Category 1B

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H300 Fatal if swallowed

    H317 May cause an allergic skin reaction

    H360 May damage fertility or the unborn child

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P272 Contaminated work clothing should not be allowed out of the workplace.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P203 Obtain, read and follow all safety instructions before use.

    Response

    P301+P316 IF SWALLOWED: Get emergency medical help immediately.

    P321 Specific treatment (see ... on this label).

    P330 Rinse mouth.

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P333+P317 If skin irritation or rash occurs: Get medical help.

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P318 IF exposed or concerned, get medical advice.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    HPMC,Lithium Carbonate,Cellulose Acetate Tow,EVA resin,Terpene Resin,PP fiber

    Location:

    Building 4, Feicui Building, No. 366 Xinshi North Road, Qiaoxi District, Shijiazhuang City, Hebei Province

    Payment Terms:

    TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    51-100

    Year of Establishment:

    2024

    Hebei Shunxing Import and Export Co., Ltd. distributes and wholesales best-selling chemical products in the consumer market, enjoying a high position among consumers. The company has established long-term and stable cooperative relationships with multiple retailers and agents. The company was founded in 2012 and has a sales history of over 10 years. There are around 160 employees. Hebei Shunxing Import and Export Co., Ltd. operates a complete range of chemical products at reasonable prices. Our company has strong strength, values credit, abides by contracts, and guarantees product quality. With the characteristics of diversified business and the principle of small profits and quick sales, we have gained the trust of more and more customers. In today's increasingly transparent product prices, our company has won the trust of our customers with its thoughtful service and excellent product quality, and has established a mutually beneficial cooperative relationship with them. The company will continue to make friends from all walks of life in an honest and mutually beneficial manner, warmly welcoming friends from all walks of life。

    The company's main products are HPMC, PM, MDEA, LAS60%, Tween (R) 80, EDTA,white oil and so on.Most of them belong to general organic chemicals

  • Inquiry History
    11 Inquiries
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