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Nootropics peptides powder high quality CAS 1401708-83-5 Dihexa with different specification

Name: Nootropics peptides powder high quality CAS 1401708-83-5 Dihexa with different specification
Brand: subi
SKU: pr2409101331
Price: 1 USD
Availability: InStock

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CAS No.:

1401708-83-5

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Shenzhen

Brand:

subi

Packaging:

bag/vials/box

Sample Available:

Yes

Price valid (until):

2024-10-10

Contact Supplier

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Jinshu Peptide Co.,Ltd

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents

Average Lead Time:

3 days

Qualification:

Main Products:

peptone

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Product Description
Seller Information
Inquiry History

Description

Product Detail

Common Name	Dihexa
CAS Number	1401708-83-5	Molecular Weight	504.662
Density	1.1±0.1 g/cm3	Boiling Point	866.2±65.0 °C at 760 mmHg
Molecular Formula	C27H44N4O5	Melting Point	N/A
MSDS	N/A	Flash Point	477.6±34.3 °C

Dihexa (PNB-0408), an oligopeptide reagent, is an angiotensin IV analog with oral activity and permeability of the blood-brain barrier. Dihexa binds to Hepatocyte Chemicalbook Growth Facto with high affinity, with a Kd value of 65pM, and enhances its activity on the receptor c-Met. Dihexa has shown excellent antipsychotic activity and improved cognitive function in animal models.

Dihexa dramatically improves cognitive function in animal models of Alzheimer's disease-like mental impairment. In an assay of neurotrophic activity, Dihexa was found to be seven orders of magnitude more potent than brain-derived neurotrophic factor.

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Why choose us

1. All peptides and raws purity >=99% purity

Many HPLC test reports are available (Janoshik).
2. 100% Safe delivery
3. Oversea warehouses and stocks: USA, Canada, Europe and Australia.
4. Cheapest prices in the market, unbeatable！
5. Payment options: Credit card, bank transfer, wise, alipay, apple pay, google pay, wechat, bitcoin,usdt,Remitly,Money gram

Peptide Storage Guidelines: General Tips

When storing peptides, remember to:

• Store peptide in a cold, dry, dark place
• Avoid repeated freezing and thawing of peptide
• Avoid overexposure to the air
• Avoid light exposure
• Avoid storing peptides in solution long term
• Aliquot peptide according to experimental requirements

Package Specifications

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How to proceed an order?
Step 1: When you intended to buy something, pls send me an inquiry by email.
Step2: I will reply you with a quotation as soon as I receive you inquiry.
Step3: We will negotiate products, price, package, payment methods and so on.
Step4: You arrange the payment.
Step5: I will arrange the shipment after receiving you money.
Step6: The tracking number of the parcel will be sent to you.
Step7: Trace the tracking number on website until you receive it.

FAQ：

Q1: Are you trading company or manufacturer?

A1: We are chemical manufacturerin China. So we can provide wholesale price.

Q2: Why is the quoted price different from the listed price?
A2: As we all know, the price of chemicals is not fixed, butfluctuates with the market.
Q3: Has the quality of your products passed the test of a third-party authoritative testing agency?
A3: Yes, all products are strictly tested by our quality control before shipment, and the quality assurance is confirmed and approved by third-party laboratories in China, the United States, Canada, Germany, the United Kingdom, Italy, France and other
countries. If you choose us, we will guarantee to provide you with the highest quality products and services.
Q4: If the inspection result can not meet the agreement between the two sides, can you bear all the losses caused by this?
A4: Yes, we can. We guarantee that the samples provided will meet the needs of our clients and we will bear the risk of default.
Q5: How can I get samples, how much is the MOQ, and how can I confirm the product quality?
A5: We can offer you free samples of our existing products, the delivery time is about 1-3 days, you only need to pay the sample shipping cost. Our MOQ starts from 1g-1000g. Confirm the product quality You can send us your product specifications and parameter requirements, we will manufacture the product according to your parameter requirements or provide according to the sample quality parameters.
Q6: How to make payment? What are your payment terms?
A6: We accept Alibaba trade assurance; Delivery after payment only. We can accept Bitcoin, Paypal, bank TT to company, bank TT to private account.
Q7: Are there any discounts?
A7: Yes, for bulk purchase orders, we always support with better price.
Q8: How and when to deliver goods?
A8: We delivery goods by Express, USA & EU special line/Royal Mail/UPS/USPS/DHL/Fedex/EMS/E packet.By sea or by air are also used. The delivery time is about 7-20 days after confirming the payment. Delivery times vary from country to country. (excluding Chinese holidays)

Q9: Why choose our supplier?

A9:We provide pre-sales and after-sales technical consulting services.

ECHEMI Editorial Reference

Dihexa is a synthetic peptide-based compound and angiotensin IV analog. As a research and pharmaceutical raw material, Dihexa is characterized by its defined molecular structure and peptide properties. It is primarily used for research, analytical testing, compound evaluation, and pharmaceutical development.

Certificates

Basic Info

Product Name:

Dihexa

Other Name:

L-Isoleucinamide,N-(1-oxohexyl)-L-tyrosyl-N-(6-amino-6-oxohexyl)-;N-(1-Oxohexyl)-L-tyrosyl-N-(6-amino-6-oxohexyl)-L-isoleucinamide;Dihexa;N-Hexanoic-Tyr-Ile-(6)aminohexanoic amide

CAS No.:

1401708-83-5

Molecular Formula:

C27H44N4O5

InChIKeys:

InChIKey=XEUVNVNAVKZSPT-JTJYXVOQSA-N

Molecular Weight:

504.7

Exact Mass:

504.66

Categories:

Bulk Drug Intermediates

Characteristics

Density:

1.111±0.06 g/cm3(Predicted)

Boiling Point:

866.2±65.0 °C(Predicted)

Research

Class:

Angiotensin IV-derived oligopeptide / HGF-c-Met potentiator

Status:

Research compound — Not FDA approved

Mechanism:

A synthetic, orally active, blood-brain-barrier-permeable oligopeptide (Hexanoyl-Tyr-Ile-Ahx-NH₂) derived from angiotensin IV. Dihexa binds hepatocyte growth factor (HGF) with high affinity (Kd = 65 pM) and allosterically potentiates HGF activity at its receptor c-Met, promoting dendritic spinogenesis and synaptogenesis. In preclinical models it was reported to be seven orders of magnitude more potent than BDNF at promoting synapse formation. Note: the foundational 2014 paper (McCoy AT, et al. Neurobiol Learn Mem. 2014) was retracted in 2025.

EC50 (HGF Binding KD):

65 pM

Activity note:

Dihexa is an HGF potentiator, not a direct receptor agonist. It does not activate c-Met alone but markedly augments HGF-induced c-Met activation at low nanomolar HGF concentrations. Functional synaptogenic activity was reported at 10⁻¹°–10⁻⁻ M (original data now subject to retraction).

Source:

Original report: McCoy AT, et al. Neurobiol Learn Mem. 2014;115:112-120 (retracted 2025). Benoist CC, et al. J Pharmacol Exp Ther. 2014;351(3):628-637.

Clinical Development:

NCT04488419

References

PubChem:

PubChem

UNII:

9WYX65A5C2

Literature:

Benoist CC, et al. J Pharmacol Exp Ther. 2014 — HGF/c-Met mechanism; McCoy AT, et al. Neurobiol Learn Mem. 2014 — Synaptogenesis data (Retracted 2025); Athira Pharma: Fosgonimeton (prodrug) pipeline status

Disclaimer:

Dihexa is NOT FDA-approved or EMA-approved as a medicine. It is a research compound only. The foundational 2014 paper describing its synaptogenic potency was retracted in 2025. Its phosphate prodrug fosgonimeton failed a Phase 2/3 Alzheimer’s trial (LIFT-AD, 2024). This listing is for industrial and laboratory research use only. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

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Seller Information

Business Type:
Trader

Main Products:
peptone

Location:
Room A109, No. 29 Dongting Road, Hexi District, Tianjin

Payment Terms:
TT against copy of documents

Average lead Time:
3 days

Total Annual Revenue:
$2.5 million-$5 million

Total Employees:
Less than 5

Year of Establishment:
2024

Inquiry History

178 Inquiries

Country	Product	Purchase Quantity	Date Posted
Canada	Dihexa lyophilized 1401708-83-5	1	Aug 23, 2026
Canada	Dihexa 1401708-83-5	1 G	Mar 8, 2026
Bulgaria	Customized peptides high purity Dihexa with fast shipping door to door CAS 1401708-83-5	10 G	May 27, 2025
Australia	Dihexa	30 G	Oct 19, 2026
United States	Dihexa	500 G	Aug 19, 2026
United States	Dihexa	25 G	Jan 26, 2025
Russia	DIHEXA	50.00 G	Aug 14, 2024
Australia	Dihexa	1 MT	Sep 18, 2026
Hungary	Dihexa	1 G	Sep 7, 2026
Spain	Dihexa	50 MG	Aug 28, 2026
Australia	Dihexa	20 MG	Aug 7, 2026
Belgium	Dihexa	10 G	Jul 24, 2026
United States	dihexa	1 G	Jul 16, 2026
United States	Dihexa/Acetic Acid 3ml 0.6%	10 PCS	Jun 30, 2026
Philippines	dihexa	10 MG	Jun 23, 2026
Philippines	Dihexa 10mg liquid	10 MT	Jun 19, 2026
Philippines	Dihexa	50 PCS	Jun 4, 2026
China	Dihexa	1 G	May 28, 2026
Australia	dihexa	30 MG	May 26, 2026
Germany	Dihexa	5 G	May 4, 2026

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Nootropics peptides powder high quality CAS 1401708-83-5 Dihexa with different specification

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