China Factory Supply Low Price and Good Quality Mifepristone CAS 84371-65-3
1 Inquiries
84371-65-3
Pesticide Grade
99%
QINDGAO
QSC=Qingdao Baishiwei Chemical
25kg drum
2025-01-24
ghk cu
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceMifepristone is a progesterone receptor (PR) and glucocorticoid receptor (GR) antagonist with IC50s of 0.2 nM and 2.6 nM in in vitro assay.
Solid
Mifepristone is a 3-oxo-Delta(4) steroid, an acetylenic compound and a tertiary amino compound. It has a role as an abortifacient, a contraceptive drug, a synthetic oral contraceptive and a hormone antagonist. It derives from a hydride of an estrane.|Mifepristone is a progestational and glucocorticoid hormone antagonist. Its inhibition of progesterone induces bleeding during the luteal phase and in early pregnancy by releasing endogenous prostaglandins from the endometrium or decidua. As a glucocorticoid receptor antagonist, the drug has been used to treat hypercortisolism in patients with nonpituitary cushing syndrome. The two marketed forms of mifepristone are Mifeprex® (mifepristone 200mg) and Korlym™ (mifepristone 300mg). Currently under investigation for use in psychotic depression (phase 3 trials).|Mifepristone is a Progestin Antagonist. The mechanism of action of mifepristone is as a Progestational Hormone Receptor Antagonist.|Mifepristone, also known as RU-486, is a potent synthetic steroidal antiprogesterone which is used as a single dose in combination with misoprostol, a prostaglandin analogue, to induce medical abortion. Mifepristone with misoprostol have not been associated with serum enzyme elevations or with clinically apparent liver injury.|Mifepristone is a derivative of the synthetic progestin norethindrone with antiprogesterone activity. Mifepristone competitively binds to the progesterone receptor, resulting in inhibition of the effects of endogenous or exogenous progesterone. This agent also exhibits antiglucocorticoid and weak antiandrogenic activities.|A progestational and glucocorticoid hormone antagonist. Its inhibition of progesterone induces bleeding during the luteal phase and in early pregnancy by releasing endogenous prostaglandins from the endometrium or decidua. As a glucocorticoid receptor antagonist, the drug has been used to treat hypercortisolism in patients with nonpituitary CUSHING SYNDROME.Basic Info-
Product Name:
Mifepristone
Other Name:Estra-4,9-dien-3-one,11-[4-(dimethylamino)phenyl]-17-hydroxy-17-(1-propyn-1-yl)-,(11β,17β)-;Estra-4,9-dien-3-one,11-[4-(dimethylamino)phenyl]-17-hydroxy-17-(1-propynyl)-,(11β,17β)-;(11β,17β)-11-[4-(Dimethylamino)phenyl]-17-hydroxy-17-(1-propyn-1-yl)estra-4,9-dien-3-one;RU 486;RU 38486;RU 486-6;R 38486;Mifepristone;Mifegyne;Mifestone;CDB 2477;Mifeprex;17β-Hydroxy-11β-[4-(dimethylamino)-phenyl]-17α-(prop-1-ynyl)-estra-4,9-dien-3-one;C 1073;VGX 410;MTPill;Pencrofton;122742-25-0;83203-42-3
CAS No.:84371-65-3
Molecular Formula:C29H35NO2
InChIKeys:InChIKey=VKHAHZOOUSRJNA-GCNJZUOMSA-N
Molecular Weight:429.59
Exact Mass:429.59
EC Number:1806241-263-5
UNII:320T6RNW1F
DSSTox ID:DTXSID5023322
NCI Thesaurus Code:C655
Color/Form:Yellow powder
ATC Code:G03XB01|G - Genito urinary system and sex hormones
HScode:29372900
Categories:
Characteristics-
PSA:
40.5
XLogP3:4.5
Appearance:1
Density:1.2±0.1 g/cm3
Melting Point:150 °C
Boiling Point:628.6±55.0 °C at 760 mmHg
Flash Point:334.0±31.5 °C
Refractive Index:1.623
Water Solubility:Poorly soluble
Storage Conditions:2-8°C
Vapor Pressure:8.0X10-14 mm Hg at 25 deg C /Estimated/
Specific rotation:D20 +138.5° (c = 0.5 in chloroform)
Henrys Law Constant:Henry's Law constant = 5.0X10-13 atm-cu m/mole at 25 °C /Estimated/
Experimental Properties:Hydroxyl radical reaction rate constant = 5.1X10-10 cu cm/molec-sec at 25 °C /Estimated/|Ozone reaction rate constant = 1.4X10-14 cu cm/molec-sec at 25 °C /Estimated/
Hazard IdentificationClassification of the substance or mixture
Reproductive toxicity, Category 1B
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H360 May damage fertility or the unborn child
Precautionary statement(s) Prevention P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
ghk cu
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Location:
No. 33688 Jingshi East Road, High-tech Zone, Jinan City, Shandong Province, Jinan Comprehensive Bonded Zone Customs supervision warehouse supporting office area 101-B3
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Payment Terms:
100% TT in advance
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Average lead Time:
120 days
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Total Annual Revenue:
$1 million-$2.5 million
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Total Employees:
11-50
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Year of Establishment:
2021
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted 
United States
Mifepristone
1 G May 24, 2024 Post an enquiry for this product
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