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Lubiprostone 136790-76-6 99%

Unit Price:

$300-311/G FOB

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CAS No.:

136790-76-6

Port:

shanghai

Packaging:

1G 10G 100G

Price valid (until):

2029-07-26

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Chong Da Prostaglandin Fine Chemicals Co., Ltd

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

prostaglandins,Polymyxin B sulfate,Clemizole hydrochloride,1,4-Diacetylbenzene,Estradiol valerate ,IMD 0354

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Product Description
Seller Information

Description

Lubiprostone(SPI-0211;RU0211) is a gastrointestinal agent used for the treatment of idiopathic chronic constipation. Target: Others Lubiprostone is a bicyclic fatty acid derived from prostaglandin E1 that acts by specifically activating ClC-2 chloride channels on the apical aspect of gastrointestinal epithelial cells, producing a chloride-rich fluid secretion. These secretions soften the stool, increase motility, and promote spontaneous bowel movements (SBM). From Wikipedia.

I tems	S pecifications	Results
Description	White crystals or crystalline powder odorlessl	Conform
Identification	HPLC, IR	Conform
Water	< 0.5 %	0.2 1 %
Single impurities	≤ 0.3 %	0.1 6 %
Total impurities	≤ 2 .0 %	0. 4 %
Residue on Ignition	≤ 0.1%	0.04%
Residue Solvent	N-Hexane ≤ 0.029% Ethyl acetate ≤ 0.5%	Not detectable Not detectable
P urity by HPLC	> 9 8 .0%	99. 6 %

Basic Info

Product Name:

(11α)-16,16-Difluoro-11-hydroxy-9,15-dioxoprostan-1-oic acid

Other Name:

Prostan-1-oic acid,16,16-difluoro-11-hydroxy-9,15-dioxo-,(11α)-;(11α)-16,16-Difluoro-11-hydroxy-9,15-dioxoprostan-1-oic acid;RU 0211;Lubiprostone

CAS No.:

136790-76-6

Molecular Formula:

C20H32F2O5

InChIKeys:

InChIKey=DBVFKLAGQHYVGQ-BFYDXBDKSA-N

Molecular Weight:

390.4618864

Exact Mass:

390.46

EC Number:

603-977-7

DSSTox ID:

DTXSID5048639

HScode:

2918990090

Categories:

Other Chemical Drugs

Characteristics

PSA:

83.8

XLogP3:

4.3

Appearance:

white, odorless crystals or crystalline powder

Density:

1.2±0.1 g/cm3

Melting Point:

56-59°C

Boiling Point:

532.3ºC at 760 mmHg

Flash Point:

275.7±30.1 °C

Refractive Index:

1.486

Water Solubility:

Practically insoluble

Storage Conditions:

-20°C Freezer

Vapor Pressure:

1.49E-13mmHg at 25°C

See More (11α)-16,16-Difluoro-11-hydroxy-9,15-dioxoprostan-1-oic acid Properties 

Hazard Identification

Classification of the substance or mixture

Skin irritation, Category 2

Eye irritation, Category 2

Specific target organ toxicity â single exposure, Category 3

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation
Prevention	P264 Wash ... thoroughly after handling. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area.
Response	P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P319 Get medical help if you feel unwell.
Storage	P403+P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More (11α)-16,16-Difluoro-11-hydroxy-9,15-dioxoprostan-1-oic acid Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
prostaglandins,Polymyxin B sulfate,Clemizole hydrochloride,1,4-Diacetylbenzene,Estradiol valerate,IMD 0354

Location:
NO.1585 JIUYE ROAD, QINGPU DISTRICT, SHANGHAI, CHINA

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,100% TT in advance

Average lead Time:
7

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
11-50

Year of Establishment:
2011

Certifications:
ISO9001

Company Profile

Founded in 2018, Shanghai Chong Da Prostaglandin Fine Chemicals Co., Ltd. is a professional manufacturer committed to research, development and promotion of prostaglandin(PG) in both human medicine and animal health. The company also has a technical team with decades of experience in PG production.
Chong Da now has mature technology with a complete production chain, laboratory analysis system and strict product management mode,are responsible for sales as well as experiments and development of new products .
Our products are exported to more than 20 countries and regions, mainly in South America and Europe. The main products are: Cloprostenol Sodium, Latanoprost, Bimatoprost, Travoprost, Prostaglandin E1, E2, etc., and related derivatives, intermediates and extraction of impurities appearing in the production process.
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Product Name	Grade / Content	Price	Supplier Name	Details
Lubiprostone 136790-76-6	Pharmaceutical Grade/99		Shanghai RC Chemicals Co., Ltd	Inquiry