Lubiprostone 136790-76-6
136790-76-6
Pharmaceutical Grade
99%
Shanghai
Made in China
25KG/DRUM
2021-09-30
API,API Intermediates,Food supplements,Electronic Intermediates,Arochemical Intermediates,Cosmetic raw meterials
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceLubiprostone(SPI-0211;RU0211) is a gastrointestinal agent used for the treatment of idiopathic chronic constipation.Target: OthersLubiprostone is a bicyclic fatty acid derived from prostaglandin E1 that acts by specifically activating ClC-2 chloride channels on the apical aspect of gastrointestinal epithelial cells, producing a chloride-rich fluid secretion. These secretions soften the stool, increase motility, and promote spontaneous bowel movements (SBM). From Wikipedia.
Solid
RU-0211 is a prostanoid.|Lubiprostone is an activator of chloride channels (ClC-2) in the intestine and is used for treatment of chronic constipation and irritable bowel syndrome. Lubiprostone has not been linked to serum enzyme elevations during treatment or to episodes of clinically apparent liver injury.|Member of a bicyclic fatty acid class of compounds derived from PROSTAGLANDIN E1 involved in chloride channel gating.Basic Info-
Product Name:
(11α)-16,16-Difluoro-11-hydroxy-9,15-dioxoprostan-1-oic acid
Other Name:Prostan-1-oic acid,16,16-difluoro-11-hydroxy-9,15-dioxo-,(11α)-;(11α)-16,16-Difluoro-11-hydroxy-9,15-dioxoprostan-1-oic acid;RU 0211;Lubiprostone
CAS No.:136790-76-6
Molecular Formula:C20H32F2O5
InChIKeys:InChIKey=DBVFKLAGQHYVGQ-BFYDXBDKSA-N
Molecular Weight:390.4618864
Exact Mass:390.46
EC Number:603-977-7
DSSTox ID:DTXSID5048639
HScode:2918990090
Categories:
Characteristics-
PSA:
83.8
XLogP3:4.3
Appearance:white, odorless crystals or crystalline powder
Density:1.2±0.1 g/cm3
Melting Point:56-59°C
Boiling Point:532.3ºC at 760 mmHg
Flash Point:275.7±30.1 °C
Refractive Index:1.486
Water Solubility:Practically insoluble
Storage Conditions:-20°C Freezer
Vapor Pressure:1.49E-13mmHg at 25°C
Hazard IdentificationClassification of the substance or mixture
Skin irritation, Category 2
Eye irritation, Category 2
Specific target organ toxicity â single exposure, Category 3
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
Storage P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Distributor
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Main Products:
API,API Intermediates,Food supplements,Electronic Intermediates,Arochemical Intermediates,Cosmetic raw meterials
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Location:
RM 916,Yinqiao Mansion,No.58 Jinxin Road,Pudong,Shanghai,China.
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A
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Average lead Time:
10
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Total Annual Revenue:
$10 million-$25 million
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Total Employees:
51-100
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Year of Establishment:
2006
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Country Product Purchase Quantity Date Posted Post an enquiry for this product