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Vitamin B3 /Niacinamide/ Nicotinamide Powder

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CAS No.:

98-92-0

Port:

Amsterdam

Packaging:

25KG Drum

Price valid (until):

2024-10-18

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Alpha Distribution BV

Company Type:

Distributor

Location:

Netherlands

Payment Terms:

TT against copy of documents,L/C,TT against B/L draft before shipment

Average Lead Time:

45 days

Qualification:

Main Products:

ethanol,ascorbic acid,acetone,Poly(ethylene) LDPE,Polypropylene,sodium carbonate

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Product Description
Seller Information
Inquiry History

Description

Nicotinamide

Nicotinamide Product Details

1. Chemical Information:

Chemical Name: Nicotinamide
Chemical Formula: C₆H₆N₂O
CAS Number: 98-92-0
Molecular Weight: 122.14 g/mol
Appearance: White to pale yellow crystalline powder

2. Forms Available:

Powder: High-purity, crystalline form used in formulations.
Serums: Concentrated solutions formulated for targeted skincare applications.
Creams and Lotions: Moisturizers that incorporate nicotinamide for skin benefits.
Dietary Supplements: Available in capsules, tablets, or powdered form for oral consumption.

3. Purity Levels:

Typically available in purities of 95% to 100%, with higher purity levels preferred for skincare applications.

4. Applications:

Skincare Products: Used in serums, moisturizers, cleansers, masks, and sunscreens.
Cosmetics: Incorporated into foundations and BB creams for added skincare benefits.
Dietary Supplements: Promotes overall health, particularly skin and metabolic health.

Advantages of Nicotinamide

Skin Benefits:
- Brightening: Helps reduce hyperpigmentation and improves overall skin tone.
- Anti-Aging: Stimulates collagen production, helping to minimize fine lines and wrinkles.
- Oil Control: Regulates sebum production, making it effective for oily and acne-prone skin.
- Barrier Repair: Strengthens the skin’s natural barrier, enhancing moisture retention and overall hydration.
- Anti-Inflammatory: Soothes redness and irritation, making it suitable for sensitive skin types.
Health Benefits:
- Metabolic Support: Plays a vital role in energy metabolism and converting food into energy.
- Nervous System Health: Supports neuronal function and overall nervous system health.
Safety Profile:
- Generally well-tolerated with minimal risk of irritation. Suitable for all skin types, including sensitive skin.
Versatility:
- Easily blends with other skincare ingredients like hyaluronic acid, peptides, and retinol, enhancing their efficacy.
Non-Phototoxic:
- Does not increase skin sensitivity to sunlight, making it safe for daily use, even in sunny conditions.
Stability:
- Stable under a variety of conditions, which allows it to maintain its efficacy in formulations over time.

Conclusion

Nicotinamide is a powerful ingredient with extensive benefits for skincare and overall health. Its ability to improve skin texture, tone, and barrier function makes it a popular choice in both cosmetic and health products. If you have specific applications or need more detailed information, feel free to ask!

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Items	Specifications

ECHEMI Editorial Reference

It is white needle crystal or crystalline powder, no smell or odor slightly, slightly bitter taste. The relative density is 1.4, melting point is 131-132 ℃.1 g of the above the product is soluble in 1 ml of water, 1.5 ml ethanol or 10 ml glycerin, insoluble in ether. The pH of 10% aqueous solution is 6.5-7.5. in dry air to light and heat stability, in alkaline or acidic solution, heating generation to nicotinic acid. Rats by oral LD502.5-3.5g/kg ADI value does not make special provisions (ECC,
Nicotinamide is a white powder. (NTP, 1992)|DryPowder; OtherSolid|Solid|WHITE CRYSTALLINE POWDER.
Nicotinamide is a white powder. (NTP, 1992)|Nicotinamide is a pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group. It has a role as an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor, a metabolite, a cofactor, an antioxidant, a neuroprotective agent, an EC 3.5.1.98 (histone deacetylase) inhibitor, an anti-inflammatory agent, a Sir2 inhibitor, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a mouse metabolite, a human urinary metabolite and a geroprotector. It is a vitamin B3, a pyridinecarboxamide and a pyridine alkaloid. It derives from a nicotinic acid.|Mediatric is a DEA Schedule III controlled substance. Substances in the DEA Schedule III have a potential for abuse less than substances in Schedules I or II and abuse may lead to moderate or low physical dependence or high psychological dependence.|An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.|Vitamin B refers to several water soluble vitamins often found together in foods, all of which are necessary for normal growth and metabolism, but none of which are synthesized in adequate amounts by humans. The common forms of vitamin B include vitamin B1 (thiamine), B2 (riboflavin), B3 (niacin), B6 (pyridoxine) and B12 (cyanocobalamin). Except for niacin (when given in high doses), there is no evidence that the other B vitamins, in physiologic or even super-physiologic high doses cause liver injury or jaundice. The major forms of vitamin B and selected other water soluble vitamins (biotin, pantothenic acid, choline) are discussed briefly in this record.|Niacinamide is the active form of vitamin B3 and a component of the coenzyme nicotinamide adenine dinucleotide (NAD). Niacinamide acts as a chemo- and radio-sensitizing agent by enhancing tumor blood flow, thereby reducing tumor hypoxia. This agent also inhibits poly(ADP-ribose) polymerases, enzymes involved in the rejoining of DNA strand breaks induced by radiation or chemotherapy.|An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and PELLAGRA. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.

Basic Info

Product Name:

Nicotinamide

Other Name:

3-Pyridinecarboxamide;Nicotinamide;Aminicotin;Benicot;Delonin Amide;Dipegyl;NAM;Niacinamide;Nicamindon;Nicofort;Nicotilamide;Nicotine acid amide;Nicotinic acid amide;Nicotinic amide;Nicotylamide;Niocinamide;Niozymin;Pelonin amide;3-Pyridinecarboxylic acid amide;Vi-Nicotyl;Vitamin B3 (niacinamide);Vitamin B;Nicosan 2;3-Carbamoylpyridine;Pelmine;β-Pyridinecarboxamide;Nicobion;Nicosylamide;Nicovit;Niavit PP;Nicovitina;Nicamina;Nicasir;3-(Aminocarbonyl)pyridine;m-(Aminocarbonyl)pyridine;3-Amidopyridine;Papulex;Nictoamide;Pelmin;NSC 13128;NSC 27452;Vitamin B3 (nicotinamide);123574-63-0;37321-14-5;78731-47-2

CAS No.:

98-92-0

Molecular Formula:

C6H6N2O

InChIKeys:

InChIKey=DFPAKSUCGFBDDF-UHFFFAOYSA-N

Molecular Weight:

122.12500

Exact Mass:

122.12

EC Number:

202-713-4

UNII:

25X51I8RD4

DEA Code Number:

1405

ICSC Number:

1703

NSC Number:

759115|27452|13128

DSSTox ID:

DTXSID2020929

NCI Thesaurus Code:

C2327

Color/Form:

White, powder, needles from benzene|Colorless crystalline solid|White, crystalline powder|Colorless needles

ATC Code:

A11HA01|A - Alimentary tract and metabolism

HScode:

2933399090

Categories:

Organic Reagents

Characteristics

PSA:

55.98000

XLogP3:

0.88080

Appearance:

Nicotinamide is a white powder. (NTP, 1992)

Density:

1.400 g/cm³ @ Temp: 25 °C

Melting Point:

130 °C

Boiling Point:

157 °C @ Press: 5 x 10^-4 Torr

Flash Point:

182°C

Refractive Index:

1.4660 (estimate)

Water Solubility:

1000 g/L (20 ºC)

Storage Conditions:

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

Vapor Pressure:

Vapour pressure, kPa at 35°C: 3.1

Vapor Density:

Relative vapour density (air = 1): 4.2

Toxicity:

LD50 s.c. in rats: 1.68 g/kg (Brazda, Coulson)

Odor:

Odorless

Taste:

Bitter taste

PH:

10% "wt in vol" solution in water is neutral to litmus

PKA:

3.35(at 20 °C)

Henrys Law Constant:

Henry's Law constant = 2.90X10-12 atm-cu m/mol at 25 °C (est)

Dissociation Constants:

3.35 (at 20 °C)|pKa = 3.35 (conjugate acid)|kb1 = 2.24X10-11; kb2 = 3.16X10-14

Collision Cross Section:

125.3 Å² [M+H]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|129.32 Å² [M+H]+ [CCS Type: DT, Method: stepped-field]|137.3 Å² [M+Na]+ [CCS Type: DT, Method: stepped-field]|118 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine]|125.3 Å² [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|121.7 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]|125.2 Å² [M+H]+ [CCS Type: DT, Method: single field calibrated]|126.7 Å² [M+H]+

Experimental Properties:

Readily hydrolyzed to free acid by heating in acid or alkaline solution|Forms crystalline salts with acids|Hydroxyl radical reaction rate constant = 2.34X10-12 cu cm/molec sec at 25 °C (est)

Air and Water Reactions:

Water soluble.

Reactive Group:

Amides and Imides

Reactivity Profile:

An amine and amide. Acts as a weak base in solution. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. Organic amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).

Autoignition Temperature:

480 °C

Physical Dangers:

Dust explosion possible if in powder or granular form, mixed with air.

See More Nicotinamide Properties 

Hazard Identification

Classification of the substance or mixture

Eye irritation, Category 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H319 Causes serious eye irritation
Prevention	P264 Wash ... thoroughly after handling. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Prevent deposition of dust. Closed system, dust explosion-proof electrical equipment and lighting. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Separated from oxidants.

See More Nicotinamide Safety Data Sheet 

Seller Information

Business Type:
Distributor

Main Products:
ethanol,ascorbic acid,acetone,Poly(ethylene) LDPE,Polypropylene,sodium carbonate

Location:
Admiraal Banckertweg 12 2315 SR, Leiden, Zuid-Holland

Payment Terms:
TT against copy of documents,L/C,TT against B/L draft before shipment

Average lead Time:
45 days

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
11-50

Year of Establishment:
2010

Company Certificates
- business

Inquiry History

107 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	Nicotinamide	45.00 KG	Jun 13, 2025
India	Nicotinamide	25.00 KG	Jun 12, 2025
India	Nicotinamide	50.00 KG	Jun 11, 2025
India	Nicotinamide	50.00 KG	Jun 13, 2025
United States	Niacinamide	1 KG	Feb 5, 2024
India	Nicotinamide	25.00 KG	Jun 11, 2025
Egypt	Niacinamide	1.00 KG	Aug 28, 2026
Russia	Niacinamide	1 KG	Dec 2, 2024
India	Niacinamide	100.00 KG	Aug 3, 2026
Pakistan	Niacinamide	5.00 KG	Sep 14, 2026
Algeria	Niacinamide	1.00 KG	Sep 17, 2026
Denmark	Niacinamide	5.00 MT	Sep 9, 2026
India	Niacinamide	200.00 KG	Sep 2, 2026
India	Niacinamide	1.00 KG	Aug 31, 2026
India	Niacinamide	1.00 KG	Aug 22, 2026
Nigeria	Niacinamide	100.00 KG	Aug 20, 2026
Uganda	Niacinamide	500 G	Aug 13, 2026
Pakistan	Niacinamide	10.00 MT	Jul 10, 2026
India	Nicotinamide	1 KG	Jul 1, 2026
South Korea	Niacinamide	150 KG	Jun 29, 2026

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Vitamin B3 /Niacinamide/ Nicotinamide Powder

Product Description

Seller Information

Inquiry History

Nicotinamide

Nicotinamide Product Details

1. Chemical Information:

2. Forms Available:

3. Purity Levels:

4. Applications:

Advantages of Nicotinamide

Conclusion

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

Related Products

More Choices Find All Products for Sale 

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