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Home > Biochemical Engineering > Polypeptide > Dihexa for Sale > High Quality Nootropics 99% Dihexa Peptide 20mg Vials CAS 1401708-83-5 Pure Dihexa
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High Quality Nootropics 99% Dihexa Peptide 20mg Vials CAS 1401708-83-5 Pure Dihexa

178 Inquiries

Unit Price: Get Latest Price
CAS No.:

1401708-83-5

Grade:

Pharmaceutical Grade

Content:

99%

Port:

guangzhou

Brand:

XKY

Packaging:

5mg 10mg 15mg/vial 10vials/box

Sample Available:

Yes

Price valid (until):

2025-03-30

Company Type:
Trader
Location:
China
Payment Terms:
L/C,O/A,100% TT in advance
Average Lead Time:
7 days
Qualification:
Main Products:

Tirzepatide,Retatrutide,Peptides

  • Product Details

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Dihexa:

    • Neuropeptide compounds - Nootropics
      Nootropics is a neuropeptide compound that has the ability to modify brain cell receptors, can effectively promote the formation of neural connections, improve cognitive ability and memory, and its mechanism of action may be related to the regulation of the PI3K-AKT pathway. Biological activity
      Dihexa (PNB-0408), an oligopeptide agent, is an orally active, blood-brain barrier permeable angiotensin IV analog. Dihexa binds to hepatocyte growth factor (HGF) with high affinity, with a Kd value of 65pM, and enhances its activity on the receptor c-Met. Dihexa shows excellent antipsychotic activity and improves cognitive function in animal models. Dihexa has the potential to study Alzheimer's disease. Target
      Kd: 65pM (HGF)
      Reference quality standard
      Appearance: white powder
      Purity (HPLC) ≥98.0%
      Acetate content 5.0%~12.0%
      Water content ≤8.0%
      Peptide content ≥80.0%
      Amino acid composition analysis ≤±10%

    • The importance of peptides:
    • Many active substances in the human body are in the form of peptides. Peptides are involved in various fields of human hormones, nerves, cell growth and reproduction, and their importance is to regulate the physiological functions of various systems and cells in the body, activate the relevant enzyme systems in the body, promote the permeability of intermediate metabolic membranes, or control DNA transcription or affect specific protein synthesis, and ultimately produce specific physiological effects. Peptides are important substances involved in various cell functions in human body. Peptides can be synthesized into cells and regulate their functional activities. Peptides act as neurotransmitters in the body, transmitting information. Peptides can be used as transportation tools in the human body to transport various nutrients and various vitamins, biotin, calcium and trace elements beneficial to the human body to the cells, organs and tissues of the human body. Peptide is an important physiological regulator of the human body, which can comprehensively regulate the physiological function of the human body, enhance and exert the physiological activity of the human body, and it has important biological functions.

    Items Specifications

    Product Name   

     Dihexa

    CAS 

    1401708-83-5
    Molecular Formula C27H44N4O5
    Molecular weight  504.66
    Form Solid freeze-dried powder
    Storage condition  -20°C
    Purity     99%  
     Packaging Bottle, Can, Drum, Plastic Container, Vacuum Packet (According to customers' requirements)  
     Trademark Customzied accepted   

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      our conpany


    Our company is mainly engaged in the export of fine chemicals, cosmetics raw materials, food additives, pharmaceutical intermediates and other products. Our products have been exported to more than 30 countries and regions such as the United States, Japan, the United Kingdom, etc. Our products have passed ISO-9001, CE, SGS and other international certifications.

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      our advantage 


    1. High quality standards: All ingredients are tested for purity and performance.

    2. Competitive prices: We offer exceptional value without compromising quality.

    3. Customization: Solutions tailored to your specific needs and formulations.

    4. Reliable delivery: Timely and efficient transportation to ensure that your production schedule is met.

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      Packing and shipping


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    Service:
    1. Any inquiries will be replied within 5 hours.
    2. Dedication to quality, supply & service.
    3. Strictly on selecting raw materials.
    4. OEM/ODM Available.
    5. Reasonable & competitive price, fast lead time.
    6. Sample is available for your evaluation & formulation development.


      RFQ 


    1. How to make an order?
    Send me inquiry here(or contact me and let me know how much quantity you need)

    2. What's the lead time and shipping ways?

    We will delivery to the package by FEDEX, DHL paket ,EMS , UPS and by air,by sea to you after receive your payment, it would take around 7-10days to your address.

    3. How do I keep the peptides when I receive it ?
    Peptides in the form of lyophilized powder can be transported at room temperature by vacuum packaging, while polypeptides in the dissolved state need to be refrigerated at 2°C - 8°C. For long-term storage, peptides should be stored in the form of lyophilized powder store at -20°C or -80°C in a sealed container with desiccant, which can avoid the degradation of peptides to the greatest extent.

    4. What's the payment methods ?
    We could accept the payment through Paypal, T/T, Bank transfer and MoneyGram.


    Shipping information  


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    ECHEMI Editorial Reference

    Dihexa is a synthetic peptide-based compound and angiotensin IV analog. As a research and pharmaceutical raw material, Dihexa is characterized by its defined molecular structure and peptide properties. It is primarily used for research, analytical testing, compound evaluation, and pharmaceutical development.

    Basic Info
    Product Name:

    Dihexa

    Other Name:

    L-Isoleucinamide,N-(1-oxohexyl)-L-tyrosyl-N-(6-amino-6-oxohexyl)-;N-(1-Oxohexyl)-L-tyrosyl-N-(6-amino-6-oxohexyl)-L-isoleucinamide;Dihexa;N-Hexanoic-Tyr-Ile-(6)aminohexanoic amide

    CAS No.:

    1401708-83-5

    Molecular Formula:

    C27H44N4O5

    InChIKeys:

    InChIKey=XEUVNVNAVKZSPT-JTJYXVOQSA-N

    Molecular Weight:

    504.7

    Exact Mass:

    504.66

    Categories:

    Polypeptide

    Characteristics
    Density:

    1.111±0.06 g/cm3(Predicted)

    Boiling Point:

    866.2±65.0 °C(Predicted)

    Research
    Class:

    Angiotensin IV-derived oligopeptide / HGF-c-Met potentiator

    Status:

    Research compound — Not FDA approved

    Mechanism:

    A synthetic, orally active, blood-brain-barrier-permeable oligopeptide (Hexanoyl-Tyr-Ile-Ahx-NH₂) derived from angiotensin IV. Dihexa binds hepatocyte growth factor (HGF) with high affinity (Kd = 65 pM) and allosterically potentiates HGF activity at its receptor c-Met, promoting dendritic spinogenesis and synaptogenesis. In preclinical models it was reported to be seven orders of magnitude more potent than BDNF at promoting synapse formation. Note: the foundational 2014 paper (McCoy AT, et al. Neurobiol Learn Mem. 2014) was retracted in 2025.

    EC50 (HGF Binding KD):

    65 pM

    Activity note:

    Dihexa is an HGF potentiator, not a direct receptor agonist. It does not activate c-Met alone but markedly augments HGF-induced c-Met activation at low nanomolar HGF concentrations. Functional synaptogenic activity was reported at 10⁻¹°–10⁻⁻ M (original data now subject to retraction).

    Source:

    Original report: McCoy AT, et al. Neurobiol Learn Mem. 2014;115:112-120 (retracted 2025). Benoist CC, et al. J Pharmacol Exp Ther. 2014;351(3):628-637.

    Clinical Development:

    NCT04488419

    References
    PubChem:

    PubChem

    UNII:

    9WYX65A5C2

    Disclaimer:

    Dihexa is NOT FDA-approved or EMA-approved as a medicine. It is a research compound only. The foundational 2014 paper describing its synaptogenic potency was retracted in 2025. Its phosphate prodrug fosgonimeton failed a Phase 2/3 Alzheimer’s trial (LIFT-AD, 2024). This listing is for industrial and laboratory research use only. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Tirzepatide,Retatrutide,Peptides

    Location:

    Shop No. 47, Jixin Plaza, No. 26 Renmin Avenue, Renmin Street, Meilan District, Haikou City, Hainan Province

    Payment Terms:

    L/C,O/A,100% TT in advance

    Average lead Time:

    7 days

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    51-100

    Year of Establishment:

    2019

    Haikou Mingheng Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of pharmaceutical intermediates, plant extracts, and other products. Products are widely used in health products, peptides and other fields. Our plant covers an area of 1000 m². The proposed workshop will be built according to GMP standards. We provide our customers with quality products and first-class service. Now, we can provide G-KG service to our customers.

    • High-Quality Peptides: Our company specializes in premium-grade peptides, ensuring the highest standards of purity and efficacy. Each product undergoes rigorous testing to guarantee superior quality and performance.

    • Cutting-Edge Technology: We leverage the latest advancements in peptide synthesis and production technology. Our state-of-the-art facilities and innovative processes enable us to deliver peptides with exceptional precision and consistency.

    • Custom Solutions: We offer tailored peptide solutions to meet the specific needs of our clients. Whether you require bespoke formulations or custom quantities, our experienced team is dedicated to providing personalized support and solutions.

    • Extensive Expertise: With years of experience in the peptide industry, our team of experts is well-versed in the complexities of peptide development and applications. We are committed to providing insightful guidance and technical support to help you achieve your goals.

    • Comprehensive Product Range: Our diverse portfolio of peptide products covers a wide range of applications, including research, pharmaceutical development, and cosmetic formulations. This allows us to cater to various industries and meet different customer needs.

      Company Profile

     




  • Inquiry History
    178 Inquiries
    Country Product Purchase Quantity Date Posted
    Canada

    Dihexa lyophilized 1401708-83-5

    1  Aug 23, 2026
    Canada

    Dihexa 1401708-83-5

    1 G Mar 8, 2026
    Bulgaria

    Customized peptides high purity Dihexa with fast shipping door to door CAS 1401708-83-5

    10 G May 27, 2025
    Australia

    Dihexa

    30 G Oct 19, 2026
    United States

    Dihexa

    500 G Aug 19, 2026
    United States

    Dihexa

    25 G Jan 26, 2025
    Russia

    DIHEXA

    50.00 G Aug 14, 2024
    Australia

    Dihexa

    2 G Oct 19, 2026
    United States

    dihexa

    10 MG Sep 28, 2026
    Spain

    Dihexa

    100 MG Aug 30, 2026
    United Arab Emirates

    Diheza

    1 G Aug 28, 2026
    Canada

    Dihexa

    130  Aug 12, 2026
    Brazil

    dihexa

    90 MG Aug 4, 2026
    United States

    Dihexa raw powder

    10 G Jul 26, 2026
    Singapore

    Dihexa

    10 PCS Jul 15, 2026
    United States

    Dihexa

    1 G Jul 11, 2026
    Sweden

    Dihexa

    10 PCS Jul 8, 2026
    Australia

    Dihexa

    1 MT Jul 2, 2026
    United States

    Dihexa

    10 G Jun 14, 2026
    Germany

    Dihexa

    1 G May 25, 2026
    Post an enquiry for this product
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