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High quality Dihexa Peptide purity 99% fast delivery door to door

TDS 168 Inquiries

Unit Price:

$60/UNIT FOB

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CAS No.:

1401708-83-5

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shenzhen

Brand:

XSY

Packaging:

plastic bottle

Price valid (until):

2029-11-29

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Shandong Xinshunyue Energy Co., Ltd.

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Retatrutide,Tirzepatide,Semaglutide,GHK-CU,MOTS-C,TB500

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Product Description
Seller Information
Inquiry History

Description

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Dihexa:

Neuropeptide compounds - Nootropics
Nootropics is a neuropeptide compound that has the ability to modify brain cell receptors, can effectively promote the formation of neural connections, improve cognitive ability and memory, and its mechanism of action may be related to the regulation of the PI3K-AKT pathway. Biological activity
Dihexa (PNB-0408), an oligopeptide agent, is an orally active, blood-brain barrier permeable angiotensin IV analog. Dihexa binds to hepatocyte growth factor (HGF) with high affinity, with a Kd value of 65pM, and enhances its activity on the receptor c-Met. Dihexa shows excellent antipsychotic activity and improves cognitive function in animal models. Dihexa has the potential to study Alzheimer's disease. Target
Kd: 65pM (HGF)
Reference quality standard
Appearance: white powder
Purity (HPLC) ≥98.0%
Acetate content 5.0%~12.0%
Water content ≤8.0%
Peptide content ≥80.0%
Amino acid composition analysis ≤±10%
The importance of peptides:
Many active substances in the human body are in the form of peptides. Peptides are involved in various fields of human hormones, nerves, cell growth and reproduction, and their importance is to regulate the physiological functions of various systems and cells in the body, activate the relevant enzyme systems in the body, promote the permeability of intermediate metabolic membranes, or control DNA transcription or affect specific protein synthesis, and ultimately produce specific physiological effects. Peptides are important substances involved in various cell functions in human body. Peptides can be synthesized into cells and regulate their functional activities. Peptides act as neurotransmitters in the body, transmitting information. Peptides can be used as transportation tools in the human body to transport various nutrients and various vitamins, biotin, calcium and trace elements beneficial to the human body to the cells, organs and tissues of the human body. Peptide is an important physiological regulator of the human body, which can comprehensively regulate the physiological function of the human body, enhance and exert the physiological activity of the human body, and it has important biological functions.

Items	Specifications
Product Name	Dihexa
CAS	1401708-83-5
Molecular Formula	C27H44N4O5
Molecular weight	504.66
Form	Solid freeze-dried powder
Storage condition	-20°C
Purity	99%
Packaging	Bottle, Can, Drum, Plastic Container, Vacuum Packet (According to customers' requirements)
Trademark	Customzied accepted

Why Choose Us ？

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Our service

1.We supply Peptides, APIs & Intermediates and so on to satisfy your needs;
2. We will reply you for your inquiry in 24 hours;
3. Strictly on selecting raw materials . Our Q&C team will inspect every product quality strictly before delivery

4. Reasonable & competitive price, fast lead time ;

5. After delivery, we will track the products for you once every two days, until you get the products. When you got the goods, if you have any questions about the problem, contact with us, we will offer the solve way for you ;

6. 100% safe delivery, guaranteed delivery .

Packaging

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Payment

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Delivery

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FAQ

Q:Can i get free sample ? A: Yes, most product we can send you small free sample, you just need to pay the shipping cost .

Q:Which payment method you accept? A: We accept bank transfer,T/T,PayPal,Credit card etc. and more bigger order we accept L/C at sight

Q: Can i get tracking number after shipment ? and how long does the shipping take? A: After shipment we will offer you tracking no and tell you the website to track the package, usually the shipping time is 3-7days,but for some customers have no ability to declare customs, we use special line route to ship the package, it will take 10-12days to arrive,make sure 100% delivery

Q: How can you guarantee the quality ? A: All products we can supply you test report &you can also send our product to the third party to do test, if it is fake,we will full refund you.

Q: How to store it? A: If it hasn't been opened, just put it in cool dry place, if it is opened, you may put it in cold storage for 2-5 degree condition.

Q: How to order this product? A: You can click "contact Supplier" , or write an email to my inbox, and send us a inquiry, leave your number if possible, we will contact with you as soon as possible, then we can talk order details.

Q: How about the delivery time? A: Shipped within 48 hours after payment is received.Small orders are shipped via express door-to-door.The goods arrive in about7-10 days.

Q：ls cash on delivery ? A:in most cases,we don't support cash on delivery.

Q: How much is the commodity? A: As we all know, the price of chemicals is not fixed, but fluctuates with the market. You need to contact me to get the latest product price, we promise to give you the most favorable price.

Q:About the after-sale service? A:After purchasing the products from our Company, we have a professional technical team and after-sales team to serve you and solve all your problems in the future.

Company infor

Shandong Xinshunyue was established in 2024 with strong research and development capabilities and superb synthesis technology, as well as advanced quality control measures. Effectively promote the joint venture and cooperation with the major enterprises, manufacturers, with the idea of industrial development to serve the society and the majority of users. We always adhere to the market demand as the orientation, constantly synthesizing new high-tech chemical products and medical intermediates, mainly exported to the United States, Europe, India, South Africa, Nigeria and other countries and regions, has a wealth of export experience, to ensure transportation safety, can let each customer as soon as possible to safely receive the goods.

ECHEMI Editorial Reference

Dihexa is a synthetic peptide-based compound and angiotensin IV analog. As a research and pharmaceutical raw material, Dihexa is characterized by its defined molecular structure and peptide properties. It is primarily used for research, analytical testing, compound evaluation, and pharmaceutical development.

Certificates

Basic Info

Product Name:

Dihexa

Other Name:

L-Isoleucinamide,N-(1-oxohexyl)-L-tyrosyl-N-(6-amino-6-oxohexyl)-;N-(1-Oxohexyl)-L-tyrosyl-N-(6-amino-6-oxohexyl)-L-isoleucinamide;Dihexa;N-Hexanoic-Tyr-Ile-(6)aminohexanoic amide

CAS No.:

1401708-83-5

Molecular Formula:

C27H44N4O5

InChIKeys:

InChIKey=XEUVNVNAVKZSPT-JTJYXVOQSA-N

Molecular Weight:

504.7

Exact Mass:

504.66

Categories:

Polypeptide

Characteristics

Density:

1.111±0.06 g/cm3(Predicted)

Boiling Point:

866.2±65.0 °C(Predicted)

Research

Class:

Angiotensin IV-derived oligopeptide / HGF-c-Met potentiator

Status:

Research compound — Not FDA approved

Mechanism:

A synthetic, orally active, blood-brain-barrier-permeable oligopeptide (Hexanoyl-Tyr-Ile-Ahx-NH₂) derived from angiotensin IV. Dihexa binds hepatocyte growth factor (HGF) with high affinity (Kd = 65 pM) and allosterically potentiates HGF activity at its receptor c-Met, promoting dendritic spinogenesis and synaptogenesis. In preclinical models it was reported to be seven orders of magnitude more potent than BDNF at promoting synapse formation. Note: the foundational 2014 paper (McCoy AT, et al. Neurobiol Learn Mem. 2014) was retracted in 2025.

EC50 (HGF Binding KD):

65 pM

Activity note:

Dihexa is an HGF potentiator, not a direct receptor agonist. It does not activate c-Met alone but markedly augments HGF-induced c-Met activation at low nanomolar HGF concentrations. Functional synaptogenic activity was reported at 10⁻¹°–10⁻⁻ M (original data now subject to retraction).

Source:

Original report: McCoy AT, et al. Neurobiol Learn Mem. 2014;115:112-120 (retracted 2025). Benoist CC, et al. J Pharmacol Exp Ther. 2014;351(3):628-637.

Clinical Development:

NCT04488419

References

PubChem:

PubChem

UNII:

9WYX65A5C2

Literature:

Benoist CC, et al. J Pharmacol Exp Ther. 2014 — HGF/c-Met mechanism; McCoy AT, et al. Neurobiol Learn Mem. 2014 — Synaptogenesis data (Retracted 2025); Athira Pharma: Fosgonimeton (prodrug) pipeline status

Disclaimer:

Dihexa is NOT FDA-approved or EMA-approved as a medicine. It is a research compound only. The foundational 2014 paper describing its synaptogenic potency was retracted in 2025. Its phosphate prodrug fosgonimeton failed a Phase 2/3 Alzheimer’s trial (LIFT-AD, 2024). This listing is for industrial and laboratory research use only. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

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Seller Information

Business Type:
Trader

Main Products:
Retatrutide,Tirzepatide,Semaglutide,GHK-CU,MOTS-C,TB500

Location:
zibo

Payment Terms:
TT against copy of documents,D/A,O/A,100% TT in advance

Total Employees:
5-10

Year of Establishment:
2025

CoAs a peptide manufacturer, our products include Retatrutide, Tirzepatide, semaglutide, etc. Our products are of good quality and high purity. Welcome to consult and place an order.

Inquiry History

168 Inquiries

Country	Product	Purchase Quantity	Date Posted
Canada	Dihexa lyophilized 1401708-83-5	1	Aug 23, 2026
Canada	Dihexa 1401708-83-5	1 G	Mar 8, 2026
Bulgaria	Customized peptides high purity Dihexa with fast shipping door to door CAS 1401708-83-5	10 G	May 27, 2025
United States	Dihexa	500 G	Aug 19, 2026
United States	Dihexa	25 G	Jan 26, 2025
Russia	DIHEXA	50.00 G	Aug 14, 2024
Spain	Dihexa	50 MG	Aug 28, 2026
Australia	Dihexa	20 MG	Aug 7, 2026
Belgium	Dihexa	10 G	Jul 24, 2026
United States	dihexa	1 G	Jul 16, 2026
United States	Dihexa/Acetic Acid 3ml 0.6%	10 PCS	Jun 30, 2026
Philippines	dihexa	10 MG	Jun 23, 2026
Philippines	Dihexa 10mg liquid	10 MT	Jun 19, 2026
Philippines	Dihexa	50 PCS	Jun 4, 2026
China	Dihexa	1 G	May 28, 2026
Australia	dihexa	30 MG	May 26, 2026
Germany	Dihexa	5 G	May 4, 2026
Netherlands	Dihexa	2 G	May 1, 2026
India	Dihexa	1 MT	Apr 24, 2026
United States	Dihexa	10 MT	Apr 16, 2026

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