 Home > Active Pharmaceutical Ingredients > Drugs Influencing Immune Function > 2-Propen-1-one, 1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-, 4-methylbenzenesulfonate (1:1) for Sale > Top Quality 99.9% Ritlecitinib Tosylate Immunoregulation API & Inflammation Inhibitor

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Top Quality 99.9% Ritlecitinib Tosylate Immunoregulation API & Inflammation Inhibitor

Name: Top Quality 99.9% Ritlecitinib Tosylate Immunoregulation API & Inflammation Inhibitor
Brand: HyperChem
SKU: pr2409301440
Price: 190 USD
Availability: InStock

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Unit Price:

$190-230/G FOB

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CAS No.:

2192215-81-7

Grade:

Pharmacy Grade; Food Grade

Content:

99.9%

Port:

Shanghai

Brand:

HyperChem

Packaging:

1kg/Bag, 2kg/Bag, 5kg/Bag, 25kg/Drum

Sample Available:

Yes

Price valid (until):

2026-10-31

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Hangzhou Hyper Chemicals Limited

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

10 days

Qualification:

Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

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Product Description
Seller Information
Inquiry History

Description

Name	Ritlecitinib Tosylate
CAS number	2192215-81-7
Synonym	Ritlecitinib tosylate Ritlecitinib toslate PF-06651600 tosylate 2192215-81-7
Related APIs #	Imatinib Mesylate - CAS: 220127-57-1 Dasatinib - CAS: 302962-49-8 Nilotinib - CAS: 641571-10-0 Bosutinib - CAS: 380843-75-4 Ponatinib - CAS: 943319-70-8 Erlotinib - CAS: 183319-69-9 Gefitinib - CAS: 184475-35-2 Lapatinib - CAS: 231277-92-2 Sorafenib - CAS: 284461-73-0 Sunitinib - CAS: 557795-19-4
Description	M echanism of Action Ritlecitinib functions by covalently binding to a specific cysteine residue (Cys-909) in JAK3, which is crucial for cytokine signaling involved in immune responses. This selective inhibition is significant because it minimizes off-target effects that are common with less selective JAK inhibitors. Applications 1. Treatment of Alopecia Areata In June 2023, Ritlecitinib was approved by the FDA for the treatment of severe alopecia areata in adults and adolescents aged 12 years and older. This condition is characterized by sudden hair loss and is believed to be an autoimmune disorder. The drug's ability to inhibit JAK3 helps modulate the immune response that contributes to hair follicle destruction. 2. Potential for Other Autoimmune Conditions Given its mechanism of action, Ritlecitinib may have potential applications in treating other autoimmune diseases where cytokine signaling plays a critical role, although further studies are needed to establish efficacy in these areas. Regulatory Status 3.Ritlecitinib has also received approval from the European Medicines Agency (EMA) in September 2023, highlighting its significance as a new therapeutic option in dermatology. Conclusion Ritlecitinib tosylate represents a promising advancement in the treatment of alopecia areata through its targeted inhibition of JAK3. As research continues, its potential applications in other autoimmune diseases may further expand its therapeutic utility.
Molecular Formula	C ₂₂ H ₂₇ N ₅ O ₄ S
Molecular Weight	457.5 g/mol
Appearance	White or almost white powder
Quality Standard	Enterprise standard; 99.99%
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition	Dry, dark and at 0-28℃ for short term (days to weeks) or 0-8 ℃ for long term (months to years).
Shelf Life	>2 years if stored properly
Sample package	Double plastic bags inside, fiber drum outside, any quantity available.
Commercial package	Aluminium Tin, Fiber drum
Origin	China

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FAQ

Q1. What is the Hyper chem payment term?
T/T advance
LC at sight
DP at sight
Trade assurance
Money gram

Q2. What is Hyper chem shipment policy?
Our policy is to strive for the quickest shipment time possible, with ready stock sample shipment typically going out the same day that your order was placed. Your satisfaction is very important to us.
For non-ready stock, please contact the Hyper Chem sales team to negotiate.

Q3. What hyper chem will provide after shipment?
For sample orders:
After shipment is done, an timely email including:

Track details (Fedex /TNT/DHL/EMS Track number)

Package photo

COA, MSDS, etc

Dispatch date & Estimated arriving time

Shipping invoice

For commercial orders
A full set of shipment documents as well as package photos can be provided
in scan-copy and original, to help customers complete the customs clearance process.

Q4. What is Hyper Chem shipment term?

By Express
DHL  FedEx  TNT  EMS
Fast:5 days around
High cost, door to door service

By Air
Suitable for more than 50kg
Fast :3-7 days Hight cost, port to port, professional broker needed

By Sea
Suitable for more than 500kg
Slow:7-45 days, Low cost, port to port, professional broker needed
We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

Q5. Does hyper chem provide a shipment return policy?
Yes, we have.
Return Policy: At Hyper chem, your satisfaction is guaranteed. If you are dissatisfied for any reason with a product, please send back the unused portion along with your packing slip and a brief note on why you were dissatisfied within 45 days of purchase for a full refund to:

Q6. What is hyper chem After-sales service
• Documents support: COA ,MSDS, MOA ,MS Report,HNMR Report,SDS,DMF
• Customer Support: Shipment clearance support, quality issue support
• Automated Customer Service: Our worldwide customers enjoy immediate 24/7 access to the HYPER CHEM support team from any location, at any time.

Company profile

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

Among them, our key client industrial sectors around the global are:

Pharmaceuticals
Nutrition Ingredients/ Dietary supplements
Cosmetic Ingredients
Food Ingredients
Veterinary API
Agriculture fertilizer
Custom Synthesis lab supply

HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.

Certificates

Basic Info

Product Name:

2-Propen-1-one, 1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-, 4-methylbenzenesulfonate (1:1)

Other Name:

2-Propen-1-one, 1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-, 4-methylbenzenesulfonate (1:1);PF-06651600 tosylate;Ritlecitinib tosylate

CAS No.:

2192215-81-7

Molecular Formula:

C22H27N5O4S

InChIKeys:

YOZLVAFWYLSRRN-NFGOAHBONA-N

Molecular Weight:

457.55

Exact Mass:

457.17837553

EC Number:

201-058-9

Color/Form:

White to off-white

Categories:

Drugs Influencing Immune Function

Seller Information

Business Type:
Trader

Main Products:
Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

Location:
Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
10 days

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2013

Company Certificates
- Certification Report by Bureau Veritas
About HyperChem

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

Our Competitiveness

One-stop supply

Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

Among all the pharmaceuticals,

90% of them with GMP certificates,

85% of them with DMF files and

50% of them passed FDA approval,

30% get CEP certificate

20% are new R&D products.

Custom Repackaging Service

We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

Quality Control/Quality Assurance

HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

Professional

Transparent Communication

Fast Reaction,

Professional Suggestion

Beyond Expectation.

We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

Inquiry History

1 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	Ritlecitinib Tosylate	100 G	Mar 24, 2026

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Top Quality 99.9% Ritlecitinib Tosylate Immunoregulation API & Inflammation Inhibitor

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