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Home > Active Pharmaceutical Ingredients > Drugs Influencing Immune Function > Ritlecitinib toslate for Sale > Top Quality 99.9% Ritlecitinib Tosylate Immunoregulation API & Inflammation Inhibitor
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Top Quality 99.9% Ritlecitinib Tosylate Immunoregulation API & Inflammation Inhibitor

TDS 1 Inquiries

Unit Price:

$190-230/G FOB

Get Latest Price
CAS No.:

2192215-81-7

Grade:

Pharmacy Grade; Food Grade

Content:

99.9%

Port:

Shanghai

Brand:

HyperChem

Packaging:

1kg/Bag, 2kg/Bag, 5kg/Bag, 25kg/Drum

Price valid (until):

2026-10-31

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

  • Product Description

  • Seller Information

  • Inquiry History

  • Description
    Name Ritlecitinib Tosylate
    CAS number 2192215-81-7
    Synonym Ritlecitinib tosylate
    Ritlecitinib toslate
    PF-06651600 tosylate
    2192215-81-7
    Related APIs #

    Imatinib Mesylate - CAS: 220127-57-1
    Dasatinib - CAS: 302962-49-8
    Nilotinib - CAS: 641571-10-0
    Bosutinib - CAS: 380843-75-4
    Ponatinib - CAS: 943319-70-8
    Erlotinib - CAS: 183319-69-9
    Gefitinib - CAS: 184475-35-2
    Lapatinib - CAS: 231277-92-2
    Sorafenib - CAS: 284461-73-0
    Sunitinib - CAS: 557795-19-4

    Description


    M echanism of Action

    Ritlecitinib functions by covalently binding to a specific cysteine residue (Cys-909) in JAK3, which is crucial for cytokine signaling involved in immune responses. This selective inhibition is significant because it minimizes off-target effects that are common with less selective JAK inhibitors.

    Applications

    1. Treatment of Alopecia Areata
    In June 2023, Ritlecitinib was approved by the FDA for the treatment of severe alopecia areata in adults and adolescents aged 12 years and older. This condition is characterized by sudden hair loss and is believed to be an autoimmune disorder. The drug's ability to inhibit JAK3 helps modulate the immune response that contributes to hair follicle destruction.

    2. Potential for Other Autoimmune Conditions
    Given its mechanism of action, Ritlecitinib may have potential applications in treating other autoimmune diseases where cytokine signaling plays a critical role, although further studies are needed to establish efficacy in these areas.
    Regulatory Status

    3.Ritlecitinib has also received approval from the European Medicines Agency (EMA) in September 2023, highlighting its significance as a new therapeutic option in dermatology.

    Conclusion
    Ritlecitinib tosylate represents a promising advancement in the treatment of alopecia areata through its targeted inhibition of JAK3. As research continues, its potential applications in other autoimmune diseases may further expand its therapeutic utility.



    Molecular Formula C 22 H 27 N 5 O 4 S
    Molecular Weight 457.5 g/mol
    Appearance White or almost white powder
    Quality Standard Enterprise standard; 99.99%
    Shipping Condition Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
    Storage Condition Dry, dark and at 0-28 for short term (days to weeks) or 0-8 for long term (months to years).
    Shelf Life >2 years if stored properly
    Sample package Double plastic bags inside, fiber drum outside, any quantity available.
    Commercial package Aluminium Tin, Fiber drum
    Origin China




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    FAQ

    Q1. What is the Hyper chem payment term?
    T/T advance
    LC at sight
    DP at sight
    Trade assurance 
    Money gram 


    Q2. What is Hyper chem shipment policy?
    Our policy is to strive for the quickest shipment time possible, with ready stock sample shipment typically going out the same day that your order was placed. Your satisfaction is very important to us.
    For non-ready stock, please contact the Hyper Chem sales team to negotiate.

     

    Q3. What hyper chem will provide after shipment?
    For sample orders: 
    After shipment is done, an timely email including:

    Track details (Fedex /TNT/DHL/EMS Track number)

    Package photo

    COA, MSDS, etc 

    Dispatch date & Estimated arriving time

    Shipping invoice

    For commercial orders
    A full set of shipment documents as well as package photos can be provided
    in scan-copy and original, to help customers complete the customs clearance process.

     

    Q4. What is Hyper Chem shipment term?

    By Express   
    DHL  FedEx  TNT  EMS                               
    Fast:5 days around                             
    High cost, door to door service

    By Air                                         
    Suitable for more than 50kg 
    Fast :3-7 days Hight cost, port to port, professional broker needed 

    By Sea
    Suitable for more than 500kg      
    Slow:7-45 days, Low cost, port to port, professional broker needed 
    We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

     

    Q5. Does hyper chem provide a shipment return policy?
    Yes, we have.
    Return Policy: At Hyper chem, your satisfaction is guaranteed. If you are dissatisfied for any reason with a product, please send back the unused portion along with your packing slip and a brief note on why you were dissatisfied  within 45 days of purchase for a full refund to:

     

    Q6. What is hyper chem After-sales service
    • Documents support: COA ,MSDS, MOA ,MS Report,HNMR Report,SDS,DMF
    • Customer Support: Shipment clearance support, quality issue support
    • Automated Customer Service: Our worldwide customers enjoy immediate 24/7 access to the HYPER CHEM support team from any location, at any time.

     

     

     

    Company profile

    Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

     

    Among them, our key client industrial sectors around the global are:

     

    Pharmaceuticals
    Nutrition Ingredients/ Dietary supplements
    Cosmetic Ingredients
    Food Ingredients
    Veterinary API
    Agriculture fertilizer
    Custom Synthesis lab supply

     

    HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.

    Certificates

    Basic Info
    Product Name:

    Ritlecitinib toslate

    Other Name:

    Ritlecitinib toslate;Ritlecitinib tosylate;UNII-EAG4T1459K;PF-06651600 tosylate;EAG4T1459K;SCHEMBL23611000;2192215-81-7

    CAS No.:

    2192215-81-7

    Molecular Formula:

    C22H27N5O4S

    InChIKeys:

    YOZLVAFWYLSRRN-VZXYPILPSA-N

    Exact Mass:

    457.17837553

    Characteristics
  • Seller Information
    Business Type:

    Trader

    Main Products:

    Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

    Location:

    Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    10

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    11-50

    Year of Establishment:

    2013

    Certifications:

    Certification Report by Bureau Veritas

    About HyperChem

    Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

    Our Competitiveness

    One-stop supply

    Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

    Among all the pharmaceuticals,

    90% of them with GMP certificates,

    85% of them with DMF files and

    50% of them passed FDA approval,

    30% get CEP certificate

    20% are new R&D products.

    Custom Repackaging Service


    We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

    Quality Control/Quality Assurance


    HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

    All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

    Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

    Professional

    Transparent Communication

    Fast Reaction,

    Professional Suggestion

    Beyond Expectation.

    We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

  • Inquiry History
    1 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Ritlecitinib Tosylate

    100 G Mar 24, 2026
    Post an enquiry for this product
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